136 results match your criteria: "Endometriosis Center[Affiliation]"

Background: Scar endometriosis (EM) is defined by the presence of endometrial-like tissue outside the uterine cavity within the scar region after abdominal or pelvic surgery. It is a form of abdominal wall EM. This systematic review addresses the question of whether women after cesarean delivery (CD) are more frequently affected by scar EM than women after other pelvic surgical procedures.

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Article Synopsis
  • The study aimed to identify factors associated with poor and improved quality of life scores (QoSL) for patients with endometriosis, while also evaluating pain symptoms after surgical excision of rectovaginal nodules.
  • It involved 116 patients who underwent laparoscopic surgery, with assessments conducted pre-surgery and two years later using specific quality of life scoring systems (EHP-30 Module C).
  • Results showed significant improvements in QoSL and pain levels, particularly with complete excision of nodules leading to better outcomes compared to incomplete excision.
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Limitations and perspectives of the novel salivary test for endometriosis: an open web-based survey study of German gynecologic healthcare providers.

Arch Gynecol Obstet

September 2024

Department of Gynecology, Obstetrics and Reproductive Medicine, Saarland University Hospital, Kirrberger Straße 100, Building 9, 66421, Homburg, Saarland, Germany.

Article Synopsis
  • A new non-invasive diagnostic test for endometriosis using salivary miRNA has been developed, but current healthcare provider practices regarding this test are unclear.
  • A web-based survey conducted from November 2023 to January 2024 assessed the opinions of gynecologic professionals, revealing that about 90% viewed the test as too costly and that most did not see it as a replacement for standard diagnostic methods.
  • Results indicated disparities in perceptions about the test's applicability and usefulness based on the level of expertise, with less experienced gynecologists having a more optimistic view compared to their specialized counterparts.
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Embryo migration is defined as the movement of embryos to implant at the exact site in the endometrial cavity during assisted reproductive technology (ART). We aimed to evaluate the impact of embryo migration on clinical pregnancy (CPR) and live birth rates (LBR) in fresh oocyte donation (OD) cycles. A total of 611 fresh OD cycles was recruited in this prospective cohort study.

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This guideline was prepared by the Turkish Society of Reproductive Medicine to define the conditions and requirements for an outsourced preimplantation genetic testing (PGT) programme in line with the experience and needs of practitioners. This guideline is intended to be a reference document for assisted reproductive technology centres, genetic diagnosis centres, non-governmental organizations working on reproductive health, legal experts, consultants working on laboratory accreditation, academicians specializing in ethical issues, and policy makers. The Consortium aims to provide recommendations addressing the challenges of genetic testing, especially PGT for monogenic diseases (PGT-M) due to the high rate of consanguineous marriage in Turkey.

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The Incidence of Endometriosis, 2014–2022. An Analysis of Nationwide Claims Data From Physicians in Private Practice.

Dtsch Arztebl Int

September 2024

Central Research Institute of Ambulatory Health Care in Germany, Department of Epidemiology and Health Care Atlas, Berlin, Germany; Charité-Universitätsmedizin Berlin, Berlin, Germany; Hannover Medical School, Institute of Epidemiology, Social Medicine and Health System Research, Hannover, Germany; Charité-Universitätsmedizin Berlin, Department of Gynecology, Endometriosis Center, Berlin, Germany.

Background: The epidemiological characterization of endometri - osis, particularly with regard to its incidence, has been inadequate to date both in Germany and other countries. The goal of this study was to determine trends in the incidence of diagnosed endometri - osis and changes in age structure at the time of first diagnosis over the period 2014-2022.

Methods: Nationwide claims data from physicians in private practice, obtained according to relevant German law (§ 295 SGB V), were used to identify the population at risk for a first assured diagnosis of endometriosis (ICD-10-GM: N80) during each year of the study period, consisting of women and girls aged 10-52 who were insured by the statutory health insurance system and for whom at least two years of prior observation were possible.

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Recurrence after surgery for endometrioma: a systematic review and meta-analyses.

Fertil Steril

December 2024

Department of Obstetrics and Gynecology, Maastricht University Medical Center (MUMC+), Maastricht, the Netherlands; GROW - School for Oncology and Reproduction, Maastricht University, Maastricht, the Netherlands.

Importance: Endometriosis is an inflammatory disease, with different forms of expression and a variety of complaints. An endometrioma, an ovarian cyst with endometrium-like lining, is one of the most common expressions of abdominal endometriosis. These endometriomas can, in addition to medical treatment, be treated surgically.

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A gluten-free diet for endometriosis patients lacks evidence to recommend it.

AJOG Glob Rep

August 2024

Department of Reproductive Medicine and Endometriosis Center, Amsterdam University Medical Center, Amsterdam, The Netherlands (van Haaps, Schreurs, and Mijatovic).

Endometriosis is an estrogen-dependent chronic disease characterized by the presence of endometriumlike tissue outside the uterus and is often associated with symptoms, such as dysmenorrhea, dysuria, dyschezia, chronic pelvic pain, and infertility. Moreover, women diagnosed with endometriosis can report gastrointestinal symptoms, including bloating, constipation or diarrhea, and abdominal cramping, which can be associated with irritable bowel syndrome and can result in the misdiagnosis of endometriosis as irritable bowel syndrome at first. Treatment usually involves hormonal therapy, pain management, surgery, and/or assisted reproductive techniques in case of infertility.

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Article Synopsis
  • Endometriosis is a long-term illness affecting many women, causing pain, difficulty getting pregnant, and a lower quality of life, but it can take years to get diagnosed.
  • The study aims to use a mobile app to gather and analyze information from women with and without endometriosis, focusing on their symptoms, lifestyle, and diet over a year.
  • The goal is to understand better how endometriosis affects women, which could lead to quicker diagnoses and finding out if certain foods make the pain and quality of life worse.
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Current medical treatment options for endometriosis associated pains are inadequate. Evidence on effects of nonsteroidal anti-inflammatory drugs is scarce. Around one third of patients are not responsive to oral contraceptives or progestins due to progesterone resistance.

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BACKGROUND: The discovery of a saliva-based micro–ribonucleic acid (miRNA) signature for endometriosis in 2022 opened up new perspectives for early and noninvasive diagnosis of the disease. The 109-miRNA saliva signature is the product of miRNA biomarkers and artificial intelligence (AI) modeling. We designed a multicenter study to provide external validation of its diagnostic accuracy.

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Except when surgery is the only option because of organ damage, the presence of suspicious lesions, or the desire to conceive, women with endometriosis-associated pain often face a choice between medical and surgical treatment. In theory, the description of the potential benefits and potential harms of the two alternatives should be standardized, unbiased, and based on strong evidence, enabling the patient to make an informed decision. However, doctor's opinion, intellectual competing interests, local availability of specific services and (mis)information obtained from social media, and online support groups can influence the type of advice given and affect patients' choices.

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The effect of surgery or medication on pain and quality of life in women with endometrioma. A systematic review and meta-analysis.

Eur J Obstet Gynecol Reprod Biol

February 2024

Department of Obstetrics and Gynaecology, Maastricht University Medical Center+, the Netherlands; GROW - School for Oncology and Reproduction, Maastricht, the Netherlands.

For patients with endometrioma it is unclear what treatment: surgery and/or medication, is more effective in reducing pain and improving quality of life (QoL). This systematic review and meta- analysis aimed to provide an overview of the existing evidence on the effects of surgery and/or medication (i.e.

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Ovarian reserve markers of women with superficial endometriosis.

Int J Gynaecol Obstet

May 2024

Endometriosis Center, Department of Obstetrics and Gynecology, Hadassah Medical Center, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.

Objective: Endometriosis affects up to 10% of reproductive age women and is associated with pelvic pain and subfertility. While previous studies have shown an association between deep and ovarian endometriosis to reduced ovarian reserve, there is no data on the effect of superficial endometriosis on ovarian reserve markers. Hence, we aimed to compare ovarian reserve markers of women with superficial endometriosis to that of women without endometriosis.

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Investigating the medical journey of endometriosis-affected women: Results from a cross-sectional web-based survey (EndoVie) on 1,557 French women.

J Gynecol Obstet Hum Reprod

February 2024

Université de Paris-Cité, Faculté de Santé, Faculté de Médecine Paris Centre, Assistance Publique-Hôpitaux de Paris, Hôpital Universitaire Paris Centre, Centre Hospitalier Universitaire Cochin, Service de Gynécologie-Obstétrique II et de Médecine de la Reproduction, Paris, France; Université de Paris, Department of Infection, Immunity, Inflammation, INSERM U1016, Institut Cochin, Paris, France. Electronic address:

Article Synopsis
  • - This study explored the medical experiences and quality of life of French women affected by endometriosis, focusing on their symptoms and treatment journey from onset to management.
  • - A web-based survey conducted in early 2020 gathered responses from 1,557 women, revealing an average diagnostic delay of 7 years, with many experiencing severe symptoms and pain before receiving treatment.
  • - The findings highlight the significant negative impacts of endometriosis on women's daily lives, underscoring the need to reduce diagnostic delays and establish specialized treatment centers for better management of the condition.
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Pelvic surgery for endometriosis is associated with a risk of bladder and digestive sequelae. Sacral neuromodulation (SNM) has been shown to be effective in the treatment of overactive bladder (OAB) and voiding dysfunction (VD). This study aimed to evaluate the efficacy of sacral neuromodulation (SNM) in treating voiding dysfunction (VD) following endometriosis surgery.

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Study Question: What is the influence of dietary interventions, namely the low fermentable oligo-, di-, mono-saccharides, and polyols (Low FODMAP) diet and endometriosis diet, on endometriosis-related pain and quality of life (QoL) compared to a control group?

Summary Answer: After adhering to a dietary intervention for 6 months, women with endometriosis reported less pain and an improved QoL compared to baseline whereas, compared to the control group, they reported less bloating and a better QoL in 3 of 11 domains.

What Is Known Already: Standard endometriosis treatment can be insufficient or may be accompanied by unacceptable side effects. This has resulted in an increasing interest in self-management strategies, including the appliance of the Low FODMAP diet and the endometriosis diet (an experience-based avoidance diet, developed by women with endometriosis).

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Objective: To evaluate the changes in the ultrasound characteristics of decidualized non-ovarian endometriotic lesions that occur during pregnancy and after delivery.

Methods: This was a prospective observational cohort study carried out at a single tertiary center between December 2018 and October 2021. Pregnant women with endometriosis underwent a standardized transvaginal ultrasound examination with color Doppler imaging once in every trimester and after delivery.

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Article Synopsis
  • Endometriosis is when tissue similar to the lining of the uterus grows outside of it, causing pain and other symptoms, but it's not clear why this happens.
  • Some people think that eating a gluten-free diet might help reduce pain from endometriosis, but research on this is mixed and not very strong.
  • Studies suggest that certain diets, like avoiding red meat and eating more fruits and vegetables, might improve symptoms, but many of these studies had issues that make the results less reliable.
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Endometriosis in the era of precision medicine and impact on sexual and reproductive health across the lifespan and in diverse populations.

FASEB J

September 2023

UCSF Stanford Endometriosis Center for Innovation, Training, and Community Outreach (ENACT), University of California, San Francisco, San Francisco, California, USA.

Endometriosis is a common estrogen-dependent disorder wherein uterine lining tissue (endometrium) is found mainly in the pelvis where it causes inflammation, chronic pelvic pain, pain with intercourse and menses, and infertility. Recent evidence also supports a systemic inflammatory component that underlies associated co-morbidities, e.g.

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Purpose: Patients often undergo repeat surgery for endometriosis, due to recurrent or residual disease. Previous surgery is often considered a risk factor for worse surgical outcome. However, data are scarce concerning the influence of subsequent endometriosis surgery.

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Objective: To evaluate blood-based biomarkers to detect endometriosis and/or adenomyosis across nine European centers (June 2014-April 2018).

Methods: This prospective, non-interventional study assessed the diagnostic accuracy of 54 blood-based biomarker immunoassays in samples from 919 women (aged 18-45 years) with suspicion of endometriosis and/or adenomyosis versus symptomatic controls. Endometriosis was stratified by revised American Society for Reproductive Medicine stage.

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