Clients' and providers' perspectives in informing a digital health intervention to improve linkage to care after Index HIV self-testing in Hai and Moshi Districts, Tanzania.

Background: Digital health interventions have the potential to improve linkage to care after HIV self-testing (HIVST). This study aimed to understand clients' and providers' perceptions of benefits, and barriers of a digital health intervention designed to improve linkage to care after HIV self-testing in Tanzania.

Methods: This exploratory qualitative research study was conducted in Hai and Moshi, districts in Kilimanjaro region, Tanzania.

Histone serotonylation in dorsal raphe nucleus contributes to stress- and antidepressant-mediated gene expression and behavior.

Mood disorders are an enigmatic class of debilitating illnesses that affect millions of individuals worldwide. While chronic stress clearly increases incidence levels of mood disorders, including major depressive disorder (MDD), stress-mediated disruptions in brain function that precipitate these illnesses remain largely elusive. Serotonin-associated antidepressants (ADs) remain the first line of therapy for many with depressive symptoms, yet low remission rates and delays between treatment and symptomatic alleviation have prompted skepticism regarding direct roles for serotonin in the precipitation and treatment of affective disorders.

Sleep and mental health among youth experiencing homelessness: A retrospective pilot diary study.

Objectives: The goal of this study was to describe the nightly sleep conditions of youth experiencing homelessness, and examine the association between sleep and mental health, both cross-sectionally and using diary data.

Methods: n = 147 youth (ages 16-24) experiencing homelessness completed a baseline survey assessing self-reported sleep and depressive and anxious symptoms. A subsample of n = 49 completed a follow-up 7-day diary study measuring nightly sleep conditions and daily depressive and somatic symptoms.

Daily association between racial discrimination and depressive symptoms among ethnically diverse adolescents: Ethnic identity as a predictor and a buffer.

Objectives: The present study assessed the association between daily racial discrimination and depressive symptoms over the course of 14 consecutive days, and the predictive and buffering effects of ethnic identity commitment and exploration.

Method: Participants were 96 high school juniors and seniors ( = 17.45, = 1.

Using Behavioral Skills Training to Teach Functional Assessment Interviewing, Cultural Responsiveness, and Empathic and Compassionate Care to Students of Applied Behavior Analysis.

Within the field of applied behavior analysis, there is a recognized need for increased training for practitioners on cultural responsiveness, as well as to improve behavior analysts' demonstration of compassion and empathy towards the families with whom they work. The present study used behavioral skills training via telehealth to teach three skillsets-functional assessment interviewing, empathic and compassionate care, and cultural responsiveness. Participants were seven graduate students who had no previous coursework in behavioral assessment and whose caseload mainly included clients who did not share the participant's cultural, ethnic, or religious backgrounds.

Histone H3 serotonylation dynamics in dorsal raphe nucleus contribute to stress- and antidepressant-mediated gene expression and behavior.

Background: Major depressive disorder (MDD), along with related mood disorders, is a debilitating illness that affects millions of individuals worldwide. While chronic stress increases incidence levels of mood disorders, stress-mediated disruptions in brain function that precipitate these illnesses remain elusive. Serotonin-associated antidepressants (ADs) remain the first line of therapy for many with depressive symptoms, yet low remission rates and delays between treatment and symptomatic alleviation have prompted skepticism regarding precise roles for serotonin in the precipitation of mood disorders.

Machine learning approaches and non-linear processing of extracted components in frontal region to predict rTMS treatment response in major depressive disorder.

Predicting the therapeutic result of repetitive transcranial magnetic stimulation (rTMS) treatment could save time and costs as ineffective treatment can be avoided. To this end, we presented a machine-learning-based strategy for classifying patients with major depression disorder (MDD) into responders (R) and nonresponders (NR) to rTMS treatment. Resting state EEG data were recorded using 32 electrodes from 88 MDD patients before treatment.

The physician CEO advantage and hospital performance during the COVID-19 pandemic: capacity utilization and patient satisfaction.

Purpose: Prior studies have shown that physician-led hospitals have several advantages over non-physician-led hospitals. This study seeks to test whether these advantages also extend to periods of extreme disruptions such as the COVID-19 pandemic, which affect bed availability and hospital utilization.

Design/methodology/approach: The authors utilize a bounded Tobit estimation to identify differences in patient satisfaction rates and in-hospital utilization rates of top-rated hospitals in the United States.

The impact of employment on treatment completion rates with DWI offenders.

Drivers under the influence of alcohol cause nearly one third of all fatal motor vehicle accidents. Ambulatory outpatient alcohol use disorder treatment has been clinically shown to increase abstinence, which could decrease the chance of subsequent DWI offences. Aiding clients in successful completion of this treatment is imperative to lower the recidivism rates of DWI offenses.

Who is doing the chores and childcare in dual-earner couples during the COVID-19 era of working from home?

In 2020-21, parents' work-from-home days increased three-and-a-half-fold following the initial COVID-19 pandemic lockdowns compared to 2015-19. At the same time, many schools offered virtual classrooms and daycares closed, increasing the demand for household-provided childcare. Using weekday workday time diaries from American Time Use Survey and looking at parents in dual-earner couples, we examine parents' time allocated to paid work, chores, and childcare in the COVID-19 era by the couple's joint work location arrangements.

Distance Education in Nutrition and Dietetics Education over the Past 30 Years: A Narrative Review.

The coronavirus disease 2019 pandemic necessitated the use of distance education, which sparked a technological transformation that was long overdue in higher education. The purpose of this narrative review is two-fold: to summarize the state of knowledge regarding distance education in nutrition and dietetics education over the past 30 years to inform recommendations for future education/research and implications for practice and to determine the influence that distance education has had on the knowledge, skills, and attitudes of both nutrition and dietetics educators and their students. A narrative review of 822 publications yielded 25 that met the search criteria.

Flavan-3-ols and Cardiometabolic Health: First Ever Dietary Bioactive Guideline.

Guideline recommendation for a plant bioactive such as flavan-3-ols is a departure from previous recommendations because it is not based on deficiencies but rather improvement in health outcomes. Nevertheless, there is a rapidly growing body of clinical data reflecting benefits of flavan-3-ol intake that outweigh potential harms. Thus, the objective of the Expert Panel was to develop an intake recommendation for flavan-3-ols and cardiometabolic outcomes to inform multiple stakeholders including clinicians, policymakers, public health entities, and consumers.

Crosstalk between acetylation and the tyrosination/detyrosination cycle of α-tubulin in Alzheimer's disease.

Microtubules (MTs) support a variety of neuronal functions, such as maintenance of cell structure, transport, and synaptic plasticity. Neuronal MTs are highly heterogeneous due to several tubulin isotypes and the presence of multiple post-translational modifications, such as detyrosination and acetylation. The tubulin tyrosination/detyrosination cycle is a key player in the maintenance of MT dynamics, as tyrosinated tubulin is associated with more dynamic MTs, while detyrosinated tubulin is linked to longer lived, more stable MTs.

Simultaneous electroencephalography-functional magnetic resonance imaging for assessment of human brain function.

Electroencephalography (EEG) and functional Magnetic Resonance Imaging (MRI) have long been used as tools to examine brain activity. Since both methods are very sensitive to changes of synaptic activity, simultaneous recording of EEG and fMRI can provide both high temporal and spatial resolution. Therefore, the two modalities are now integrated into a hybrid tool, EEG-fMRI, which encapsulates the useful properties of the two.

Equivalence classification, learning by exclusion, and long-term memory in pinnipeds: cognitive mechanisms demonstrated through research with subjects under human care and in the field.

Comparative cognition, as an interdisciplinary field, should utilize a holistic approach for studying cognitive mechanisms. We suggest that research with species of interest should employ both work with animals under human care and in the field. This complimentary approach allows for a better understanding of functional cognitive mechanisms themselves (i.

The Effects of Berry Polyphenols on the Gut Microbiota and Blood Pressure: A Systematic Review of Randomized Clinical Trials in Humans.

Berry consumption has beneficial effects on blood pressure. Intestinal microbiota transform berry phytochemicals into more bioactive forms. Thus, we performed a systematic review of randomized clinical trials to determine whether berry polyphenols in foods, extracts or supplements have effects on both the profile of gut microbiota and systolic and diastolic blood pressure in humans.

Telework, Wages, and Time Use in the United States.

Using data on full-time wage and salary workers from the 2017-2018 American Time Use Survey Leave and Job Flexibilities Module, we estimate hourly wage differentials for teleworkers and compare how workers allocate their time over the day when they work from home rather than the office. We find that some teleworkers earn a wage premium, but it varies by gender, parental status, and teleworking intensity. Fathers who telework earn more than fathers in office-based jobs, regardless of teleworking intensity.

Localizing Epileptic Foci Using Simultaneous EEG-fMRI Recording: Template Component Cross-Correlation.

Conventional EEG-fMRI methods have been proven to be of limited use in the sense that they cannot reveal the information existing in between the spikes. To resolve this issue, the current study obtains the epileptic components time series detected on EEG and uses them to fit the Generalized Linear Model (GLM), as a substitution for classical regressors. This approach allows for a more precise localization, and equally importantly, the prediction of the future behavior of the epileptic generators.

Analyzing the evolution of technostress: A science mapping approach.

This paper analyzes the scientific map of technostress and the scientific production on this topic between 1982 and 2017, highlighting its structure, evolution, and trends in this field. A literature review based on bibliometric analysis of 246 records indexed in Scopus database was conducted. These publications were analyzed according to bibliometric indicators and through science maps with SciMAT.

Localizing confined epileptic foci in patients with an unclear focus or presumed multifocality using a component-based EEG-fMRI method.

Precise localization of epileptic foci is an unavoidable prerequisite in epilepsy surgery. Simultaneous EEG-fMRI recording has recently created new horizons to locate foci in patients with epilepsy and, in comparison with single-modality methods, has yielded more promising results although it is still subject to limitations such as lack of access to information between interictal events. This study assesses its potential added value in the presurgical evaluation of patients with complex source localization.

The microtubule cytoskeleton at the synapse.

In neurons, microtubules (MTs) provide routes for transport throughout the cell and structural support for dendrites and axons. Both stable and dynamic MTs are necessary for normal neuronal functions. Research in the last two decades has demonstrated that MTs play additional roles in synaptic structure and function in both pre- and postsynaptic elements.

Demographics matter: the potentially disproportionate effect of COVID-19 on hospital ratings.

Objective: To identify how features of the community in which a hospital serves differentially relate to its patients' experiences based on the quality of that hospital.

Design: A Finite Mixture Model (FMM) is used to uncover a mix of two latent groups of hospitals that differ in quality. In the FMM, a multinomial logistic equation relates hospital-level factors to the odds of being in either group.

Exploring Factors Associated with Alcohol and/or Substance Use During the COVID-19 Pandemic.

This study explored the relationship between alcohol and substance use in the general population during the early stages of COVID-19 as related to individual, family, and community stressors. A convenience sample of adults who resided in the USA and Canada was utilized. An online survey was conducted.