10 results match your criteria: "Emory Universitygrid.189967.8[Affiliation]"
Antimicrob Agents Chemother
September 2022
Division of Healthcare Quality Promotion, Centers for Disease Control and Preventiongrid.416738.f, Atlanta, Georgia, USA.
mBio
October 2022
Viral Recombination Section, HIV Dynamics and Replication Program, NCI, Frederick, Maryland, USA.
Frequent recombination is a hallmark of retrovirus replication. In rare cases, recombination occurs between distantly related retroviruses, generating novel viruses that may significantly impact viral evolution and public health. These recombinants may initially have substantial replication defects due to impaired interactions between proteins and/or nucleic acids from the two parental viruses.
View Article and Find Full Text PDFInfect Immun
August 2022
Department of Environmental and Global Health, University of Floridagrid.15276.37, Gainesville, Florida, USA.
Cholera is an acute watery, diarrheal disease that causes high rates of morbidity and mortality without treatment. Early detection of the etiologic agent of toxigenic Vibrio cholerae is important to mobilize treatment and mitigate outbreaks. Monoclonal antibody (mAb) based rapid diagnostic tests (RDTs) enable early detection in settings without laboratory capacity.
View Article and Find Full Text PDFmBio
April 2022
Division of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Carbapenem-resistant Acinetobacter baumannii (CR) is a major cause of health care-associated infections. CR is typically multidrug resistant, and infection is difficult to treat. Despite the urgent threat that CR poses, few systematic studies of CR clinical and molecular epidemiology have been conducted.
View Article and Find Full Text PDFMicrobiol Spectr
February 2022
Division of Infectious Diseases, Department of Medicine, Emory Universitygrid.189967.8, Atlanta, Georgia, USA.
Staphylococcus aureus is a prominent nosocomial pathogen that causes several life-threatening diseases, such as pneumonia and bacteremia. S. aureus modulates the expression of its arsenal of virulence factors through sensing and integrating responses to environmental signals.
View Article and Find Full Text PDFJ Bacteriol
February 2022
Emory Antibiotic Resistance Center, Emory Universitygrid.189967.8 School of Medicine, Atlanta, Georgia, USA.
Purcell and colleagues offer new insights into a major mechanism of polymyxin resistance in Gram-negative bacteria (A. B. Purcell, B.
View Article and Find Full Text PDFThe female genital tract (FGT) is an important site of human immunodeficiency virus (HIV) infection. Discerning the nature of HIV-specific local immune responses is crucial for identifying correlates of protection in HIV-exposed seronegative (HESN) individuals. The present study involved a comprehensive analysis of soluble immune mediators, secretory immunoglobulins (sIg), natural killer (NK) cells, CXCR5 CD8 T cells, T follicular helper (Tfh) cells, and T regulatory cells (Tregs) in the vaginal mucosa as well as the nature and composition of the cervicovaginal microbiome in HESN women.
View Article and Find Full Text PDFAppl Environ Microbiol
January 2022
Department of Biology, Emory Universitygrid.189967.8, Atlanta, Georgia, USA.
Many insects harbor microbial symbiotic partners that offer protection against pathogens, parasitoids, and other natural enemies. Mounting evidence suggests that these symbiotic microbes can play key roles in determining infection outcomes in insect vectors, making them important players in the quest to develop novel vector control strategies. Using the squash bug , we investigated how the presence of symbionts affected the persistence and intensity of phytopathogenic Serratia marcescens within the insect vector.
View Article and Find Full Text PDFJ Clin Microbiol
October 2021
Division of Infectious Diseases, Department of Medicine, Emory Universitygrid.189967.8 School of Medicine, Atlanta, Georgia, USA.
The utility of rapid antigen testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is measured within the context for which it is applied; diagnostic accuracy must be considered in determining if rapid antigen testing is appropriate for the clinical situation. In this issue of the , J. N.
View Article and Find Full Text PDFJ Clin Microbiol
January 2022
Department of Pathology and Laboratory Medicine, Emory Universitygrid.189967.8, Atlanta, Georgia, USA.
Infections caused by Naegleria fowleri, Acanthamoeba spp., and Balamuthia mandrillaris result in a variety of clinical manifestations in humans. These amoebae are found in water and soil worldwide.
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