Correlations between coagulation abnormalities and inflammatory markers in trauma-induced coagulopathy.

Introduction: In multiple trauma patients, the occurrence of trauma-induced coagulopathy (TIC) is closely associated with tissue damage and coagulation function abnormalities in the pathophysiological process.

Methods: This study established a multiple trauma and shock model in Sprague-Dawley (SD) rats and comprehensively utilized histological staining and radiographic imaging techniques to observe injuries in the intestine, liver, skeletal muscles, and bones. Monitoring activated partial thromboplastin time (APTT), platelet (PLT) count, respiratory rate, blood pressure, and other physiological indicators revealed time-dependent alterations in coagulation function and physiological indicators.

The Combination of Systemic Immune-Inflammation Index and Serum Procalcitonin has High Auxiliary Predictive Value for Short-Term Adverse Prognosis in Septic Shock Patients.

Background: Septic shock is the most serious complication of sepsis, with more secure and efficient biomarkers urgently needed. Systemic immune-inflammation index (SII) and serum procalcitonin (PCT) show involvement in predicting septic shock prognosis.

Objective: Herein, we explored the clinical value of the SII-PCT combination in the short-term prognosis of septic shock patients.

Clinical application of a body area network-based smart bracelet for pre-hospital trauma care.

Objective: This study aims to explore the efficiency and effectiveness of a body area network-based smart bracelet for trauma care prior to hospitalization.

Methods: To test the efficacy of the bracelet, an observational cohort study was conducted on the clinical data of 140 trauma patients pre-admission to the hospital. This study was divided into an experimental group receiving smart bracelets and a control group receiving conventional treatment.

Application of telemedicine system on the management of general patient in quarantine.

To limit the epidemic of COVID-19, most countries and regions have adopted the policy of quarantine, providing an opportunity for the development of telemedicine. This study aims to develop a telemedicine system within a quarantined district and validate its effectiveness and safety in managing a variety of diseases within the population. Appling the private network and specialized set, telemedicine system and service process were constructed in the quarantine district.

Construction of a 5G-based, three-dimensional, and efficiently connected emergency medical management system.

Background: Shenzhen is unique in its need for ad hoc responses to emergencies. The need for emergency medicine also demonstrates a trend of sustained growth.

Objective: A three-dimensional and efficiently connected emergency medical management model using fifth generation mobile communication technology (5G) was established to improve the efficiency and level of management in emergency medicine.

Hyaluronic acid and chitosan-based injectable and self-healing hydrogel with inherent antibacterial and antioxidant bioactivities.

Injectable dressings offering intrinsic antibacterial activity and antioxidation are required, because persistent bacterial infection and oxidative damage are common issues associated with chronic non-healing wounds. Herein, a versatile QCS-l-TA-l-OHA hydrogel is fabricated using ubiquitous nature derived biological macromolecules, quaternized chitosan (QCS), tannic acid (TA) and oxidant hyaluronic acid (OHA), driving by multiple dynamic interactions under physiological conditions. The hydrogel can serve as multiple functional wound dress with injectable and self-healing capabilities coupling with attractive antibacterial activity and antioxidation.

Case Report on Early Diagnosis of COVID-19.

The coronavirus disease 2019 (COVID-19) outbreak in Wuhan, China, spread rapidly throughout China and gradually to some countries abroad. How is the development of an epidemic controlled? Early diagnosis is one of the important contents in prevention and control. COVID-19 patients with early mild pneumonia often lack typical evidence to make a definitive diagnosis.

The Alterations of Copper and Zinc Homeostasis in Acute Appendicitis and the Clinical Significance.

Copper (Cu) and zinc (Zn) are involved in inflammatory process. This study was to investigate the clinical significance of Cu and Zn homeostasis alterations in acute appendicitis (AA). One hundred twenty-two AA patients and 102 healthy controls were enrolled in this study.