1 results match your criteria: "Email: zhaom@sj-hospital.org.[Affiliation]"
[Preparation of paraoxonase liposomes and their pharmacokinetics in rats].
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
November 2017
Department of Emergency, Third Central Hospital of Tianjin, Tianjin Institute of Hepatobiliary Disease, Tianjin Key Laboratory of Artificial Cell, Artificial Cell Engineering Technology Research Center of Public Health Ministry, Tianjin 300170, China (Han ZK, Jiang SW, Fu BQ); Department of Emergency, Shengjing Hospital, China Medical University, Shenyang 110004, Liaoning, China (Zhao M). Corresponding author: Zhao Min, Email:
Objective: To prepare paraoxonase 1 (PON1) liposomes, and investigate pharmacokinetics of common PON1 liposomes (L-PON1) and polyethylene glycol-modified PON1 long circulating liposomes (PEG-PON1-LCL) in rats after intravenous administration.
Methods: L-PON1 and PEG-PON1-LCL were prepared by film dispersion method. The entrapment efficiency, mean diameter and Zeta potential of the liposomes were measured, and the stability was evaluated.