IFNα induces CCR5 in CD4 T cells of HIV patients causing pathogenic elevation.

Background: Among people living with HIV, elite controllers (ECs) maintain an undetectable viral load, even without receiving anti-HIV therapy. In non-EC patients, this therapy leads to marked improvement, including in immune parameters, but unlike ECs, non-EC patients still require ongoing treatment and experience co-morbidities. In-depth, comprehensive immune analyses comparing EC and treated non-EC patients may reveal subtle, consistent differences.

Joint association and interaction of birth weight and lifestyle with hypertension: A cohort study in UK Biobank.

Low birth weight and unhealthy lifestyle are both associated with an increased risk of hypertension. The authors aimed to assess the joint association and interaction of birth weight and lifestyle with incident hypertension. The authors included 205 522 participants free of hypertension at baseline from UK Biobank.

DNA methylation clocks for estimating biological age in Chinese cohorts.

Epigenetic clocks are accurate predictors of human chronological age based on the analysis of DNA methylation (DNAm) at specific CpG sites. However, a systematic comparison between DNA methylation data and other omics datasets has not yet been performed. Moreover, available DNAm age predictors are based on datasets with limited ethnic representation.

Self-reported cycling behavior and previous history of traffic accidents of cyclists.

Background: Cyclists are vulnerable traffic users and studying the cycling behavior of professional and elite cyclists, their previous history of traffic accidents combined with the current knowledge on high-risk behaviors of this group can be a useful basis for further studies on ordinary cyclists. This study aimed to determine the relationship between cycling behavior and the previous history of traffic accidents among members of the Cycling Federation of Guilan province in 2022.

Methods: A descriptive-analytical study was performed in which the Bicycle Rider Behavior Questionnaire (BRBQ) constructed in the Porsline platform was distributed using the WhatsApp social network.

[Comparative study of percutaneous transfacet screw and pedicle screw in oblique lumbar interbody fusion for the treatment of single-level lumbar spinal stenosis].

To conduct a comparative study of radiological and clinical outcomes between percutaneous transfacet screw (TFS) and pedicle screw (BPS) in oblique lateral lumbar interbody fusion (OLIF) for single-level lumbar spinal stenosis. A retrospective cohort study. Patients who underwent OLIF with TFS or BPS for the treatment of single-level lumbar spinal stenosis at Beijing Jishuitan Hospital from January 2019 to June 2022 were retrospectively analyzed.

The effect of long-term soccer training on left ventricular structure and function in elite male youth soccer players.

Aims: Cardiac adaptations in elite, male adolescent youth soccer players have been demonstrated in relation to training status. The time course of these adaptations and the delineation of the influence of volatile growth phases from the training effect on these adaptations remain unclear. Consequently, the aims of the study were to evaluate the impact of 3 years of elite-level soccer training on changes in left ventricular (LV) structure and function in a group of highly trained elite youth male soccer players (SP) as they transitioned through the pre-to-adolescent phase of their growth.

Clinical Outcomes and Tau Pathology in Retired Football Players: Associations With Diagnosed and Witnessed Sleep Apnea.

Background And Objectives: Obstructive sleep apnea (SA) is common in older men and a contributor to negative cognitive, psychiatric, and brain health outcomes. Little is known about SA in those who played contact sports and are at increased risk of neurodegenerative disease(s) and other neuropathologies associated with repetitive head impacts (RHI). In this study, we investigated the frequency of diagnosed and witnessed SA and its contribution to clinical symptoms and tau pathology using PET imaging among male former college and former professional American football players.

Cross-Sectional Study of the Anthropometric Profile and Nutrient Status of Elite Female Ice Hockey Players: Differences by Play Position.

Both the characteristics of ice hockey and the environmental conditions in which it is played affect the maintenance of the player's nutritional status and, therefore, their state of health and performance. The primary aim of this work was to examine the anthropometric profile, estimated energy expenditure, and macronutrient and micronutrient dietary intake of elite female ice hockey players by play position. As a secondary aim, their dietary intakes were compared with the recommendations.

Maternal Malic Acid May Ameliorate Oxidative Stress and Inflammation in Sows through Modulating Gut Microbiota and Host Metabolic Profiles during Late Pregnancy.

Sows suffer oxidative stress and inflammation induced by metabolic burden during late pregnancy, which negatively regulates reproductive and lactating performances. We previously found that L-malic acid (MA) alleviated oxidative stress and inflammation and improved reproductive performances in sows. However, the mechanism underlying the MA's positive effects remains unexplored.

Maturity Status and Relative Age of Elite Taekwondo Youth Competitors-Case Study on Croatian National Team.

This study examines the maturity status and relative age effect in elite youth taekwondo Croatian National Team athletes. Measurements of biological age, maturity offset, and body composition were taken from a sample of 17 junior athletes. Differences in maturity status were observed among athletes of the same chronological age, with variations in sitting height and age at peak height velocity.

Poor quality of sleep and musculoskeletal pains among highly trained and elite athletes in Senegal.

Background: Previous studies reported that poor sleep quality (PSQ) was associated with musculoskeletal pains (MSP) and poor physical performance in athletes.

Objective: The current study aimed at determining PSQ and its associations with MSP in some sub-Saharan athletes.

Methods: A cross sectional study was conducted among 205 highly trained and 115 elite athletes (aged: 25 ± 2 years, Body mass index: 22.

Prospective and Retrospective Analysis of the Sporting Success of Elite Spanish High and Long Jumpers.

The aim of the present study was to analyze the sporting progression from U14 to senior categories of elite Spanish high and long jumpers. For prospective analysis, 300 athletes ranked top 20 at U14 were analyzed (153 female and 147 male). For retrospective analysis, 64 athletes ranked in the top 20 in the senior category were included (21 female and 43 male).

Estimating Maturity Status in Elite Youth Soccer Players: Evaluation of Methods.

Purpose: The objective of this study is to evaluate the concordance of predicted maturity status classifications (pre-, circa-, or post-peak height velocity (PHV)) relative to observed age at PHV in youth soccer players.

Methods: Longitudinal height records for 124 male soccer players were extracted from academy records spanning the 2000 to 2022 seasons. Age at PHV for each player was estimated with the Superimposition by Translation and Rotation model.

Selection-Dependent Differences in Youth Elite Basketball Players' Relative Age, Maturation-Related Characteristics, and Motor Performance.

: The aim of the present study was to investigate the influence of players' relative age, maturation-related characteristics, and motor performance tests on two different stages of talent selection (regional and national level) in youth elite basketball. : Relative age, maturation-related variables (height, weight, maturity offset, maturity timing) and motor performance (Countermovement jump, Standing long jump, Modified agility T-test, Linear sprint 20 m) of  = 68 male youth basketball players ( = 14.39 ± 0.

Body dissatisfaction, disordered eating and exercise behaviours: associations with symptoms of REDs in male and female athletes.

Objectives: Disordered eating and compulsive exercise behaviours are common among athletes and can increase the risk of relative energy deficiency in sport (REDs). Contrarily, the prevalence of muscle dysmorphia and its relationship with REDs are unknown. This cross-sectional study aimed to evaluate associations of all three with REDs symptoms.

Muscle Oximetry in Sports Science: An Updated Systematic Review.

Background: In the last 5 years since our last systematic review, a significant number of articles have been published on the technical aspects of muscle near-infrared spectroscopy (NIRS), the interpretation of the signals and the benefits of using the NIRS technique to measure the physiological status of muscles and to determine the workload of working muscles.

Objectives: Considering the consistent number of studies on the application of muscle oximetry in sports science published over the last 5 years, the objectives of this updated systematic review were to highlight the applications of muscle oximetry in the assessment of skeletal muscle oxidative performance in sports activities and to emphasize how this technology has been applied to exercise and training over the last 5 years. In addition, some recent instrumental developments will be briefly summarized.

Body Composition Changes in Male and Female Elite Soccer Players: Effects of a Nutritional Program Led by a Sport Nutritionist.

Background: Soccer is a game in constant evolution and the intensity of play is increasing. Nutrition can play a role in the physical performance of elite players, maintaining their health and facilitating recovery. It is important to cover players' energy demands, and low energy availability may therefore result in impaired performance.

Does elite European match-play affect salivary immunoglobulin-A and cortisol in soccer players? The influence of playing status and match outcome.

The aims of this study were to: a) investigate salivary immunoglobulin A (s-IgA) and cortisol (s-Cort) responses to nine competitive fixtures in starting and non- starting soccer players; and b) compare s-IgA and s-Cort responses of starters and non-starters considering match outcome. Saliva from 19 male outfield players from an elite soccer team (mean ± SD, age 26 ± 4 years; weight 80.5 ± 8.

Factors affecting the embryo production in buffalo (): A review.

Under natural and well-managed conditions, the buffalo has good reproductive and productive indices. However, embryo production (IVEP) has been used commercially to maximise the number of elite animals. In this species, several factors (donor management, culture medium, semen, conditions, embryo transfer) still affect the IVEP results.

The optimal window for reconstruction of the anterior cruciate ligament (ACL) with respect to quadriceps atrophies lies within 21 to 100 days.

Purpose: The study's objective was to determine the optimal window for anterior cruciate ligament (ACL) reconstruction with respect to quadriceps atrophies and clinical outcome.

Methods: For this retrospective, comparative study, 115 patients aged under 35 were included, who received an ACL reconstruction between 2011 and 2016. They were divided into four groups, depending on the time to surgery, to determine the optimal window for reconstruction: (group 1: ≤21 d, group 2: <21d-56d≥, group 3: >56d-100d≥, group 4: >100d).

Dementia risk factors in former contact sports participants: prospective cohort study.

Background: The elevated dementia incidence in retired contact sport participants might be explained by a higher prevalence of established risk factors for the disease relative to the general population.

Methods: In this cohort study, former elite participants active between 1920 and 1965 in soccer (N=303), boxing (N=281), and wrestling (N=318) were recruited using sports yearbooks and records of sports associations. Men in a population control group were identified using records from a compulsory medical examination (N=1712).

Salt Stress Induces Contrasting Physiological and Biochemical Effects on Four Elite Date Palm Cultivars ( L.) from Southeast Morocco.

Understanding the response of date palm ( L.) cultivars to salt stress is essential for the sustainable management of phoeniculture in Tafilalet, Morocco. It offers a promising avenue for addressing the challenges presented by the increasing salinity of irrigation waters, especially because farmers in these regions often lack the necessary knowledge and resources to make informed decisions regarding cultivar selection.