1 results match your criteria: "Electrical and Manufacturing Engineering Loughborough University Epinal Way[Affiliation]"
Gene modification strategies using AO-mediated exon skipping and CRISPR/Cas9 as potential therapies for Duchenne muscular dystrophy patients.
Eng Biol
December 2020
Centre for Biological Engineering, Wolfson School of Mechanical, Electrical and Manufacturing Engineering Loughborough University Epinal Way, Loughborough Leicestershire LE11 3TU UK.
Duchenne muscular dystrophy (DMD) is an X-linked genetic disease affecting 1 in 5000 young males worldwide annually. Patients experience muscle weakness and loss of ambulation at an early age, with ∼75% reduced life expectancy. Recently developed genetic editing strategies aim to convert severe DMD phenotypes to a milder disease course.
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