Pregnancy and Infant Outcomes in Women With Multiple Sclerosis Treated With Ocrelizumab.

Background And Objectives: Ocrelizumab labeling advises contraception for women during treatment and for 6-12 months thereafter. Because pregnancies may occur during this time, it is critical to understand pregnancy and infant outcomes in women with multiple sclerosis (MS) after ocrelizumab exposure.

Methods: Pregnancy cases reported to Roche global pharmacovigilance until 12 July 2023 were analyzed.

Family planning behavior before and during the COVID-19 pandemic.

Objective: Contraception use and follow-up visit data from before and in two periods during the coronavirus disease-2019 (COVID-19) pandemic were compared to investigate change in behavior.

Material And Methods: A retrospective study of women aged 18-49 years from New York City during three one-year time periods: pre-COVID-19 pandemic [(COV-PRE); n=4,261], early COVID-19 pandemic when the COVID-19 vaccine was not available [(COV-VACNO); n=3,365], and later COVID-19 pandemic when the COVID-19 vaccine was available [(COV-VACAV); n=4,170].

Results: There were higher odds of implant use [odds ratio (OR): 1.

Risk Factors for Acute Intraoperative Bradycardia in Patients Undergoing Gender-affirming Mastectomy.

Gender-affirming mastectomy surgery is highly desired within both transmasculine and nonbinary patient populations. The development of cardiac arrhythmias has been reported within this population. Acute intraoperative bradycardia in patients undergoing gender-affirming mastectomy has not been well described previously.

Abortion is healthcare: In what sense?

In the wake of Dobbs vs. Jackson Women's Health Organization, many nursing organizations asserted that "abortion is health care" and access to it must be protected. Such a phrase makes clear claims about the meanings of "health" and "care.

Medical student perceptions of clinical abortion training opportunities across the United States.

Federal abortion protection reversals have increased the importance of understanding and addressing regional disparities in clinical abortion training. We surveyed Medical Students for Choice leaders in July 2022 about abortion training and analyzed results by state abortion laws. Of 100 survey respondents, 50 % reported institutional access to abortion training (17.

Teratogenic effect of Misoprostol following failure of elective abortion: A case of femoral agenesis and review of the literature.

Misoprostol, a synthetic analogue of prostaglandin E1, is commonly used in gynecology, particularly in combination with mifepristone for elective abortion. Although its use is widespread, the potential teratogenic effects of misoprostol in cases of failed medical abortion have not been sufficiently explored in the medical literature. Severe congenital malformations, although rare, have been reported, raising concerns about the impact of this drug on fetal development.

Real-World Impact of GLP-1 Receptor Agonists on Endoscopic Patient Outcomes in an Ambulatory Setting: A Retrospective Study at a Large Tertiary Center.

Glucagon-like peptide receptor agonists (GLP-1 RAs) are associated with delayed gastric emptying and may increase the risk of aspiration due to retained gastric contents. There are no guidelines on peri-endoscopic use of GLP-1 RAs, and real-world outcomes in an ambulatory setting remain unknown. This study reports real-world data from an ambulatory center associated with a large tertiary hospital.

Predictors of spontaneous pregnancy loss in single ventricle physiology.

Background: Pregnant patients with single ventricle (SV) physiology carry a high risk of spontaneous pregnancy loss (SPL), yet the clinical factors contributing to this risk are not well defined.

Methods: Single-centre retrospective study of pregnant patients with SV physiology seen in cardio-obstetrics clinic over the past 20 years with chart review of their obstetric history. Patients without a known pregnancy outcome were excluded.

Selective fetal reduction of uncomplicated dichorionic twins on parental request vs ongoing twins and pregnancy outcomes: a systematic review and meta-analysis.

Objective: This study aimed to assess the effect of elective fetal reduction on maternal-fetal outcomes in uncomplicated twin pregnancies compared with ongoing twin pregnancies.

Data Sources: The data sources included PubMed, Scopus (until December 2023), and references of retrieved articles.

Study Eligibility Criteria: We included clinical studies examining the association between selective fetal reduction of uncomplicated dichorionic twins on pregnancy outcomes.

The provision of abortion in Australia: service delivery as a bioethical concern.

Despite significant progress in the legalization and decriminalization of abortion in Australia over the past decade or more recent research and government reports have made it clear that problems with the provision of services remain. This essay examines such issues and sets forth the view that such issues can and should be seen as (bio)ethical concerns. Whilst conscientious objection-the right to opt-out of provision on the basis of clear ethical reservations-is a legally and morally permissible stance that healthcare professionals can adopt, this does not mean those working in healthcare can simply elect not to be providers absent a clear ethical rationale.

An interplay between orthopaedic trauma and pregnancy-A case series of 42 patients.

Background: Pregnancy and trauma are complex situations with significant implications for maternal and fetal health. Physical and psychological trauma during pregnancy can lead to pre-term labor, abruptio-placenta, and fetal injury or death. Management of trauma is challenging due to physiological and anatomical changes, which can affect fracture management and the risk of radiation exposure.

Detecting and Dating Early Non-live Pregnancy Outcomes: Generation of a Novel Pregnancy Algorithm From Norwegian Linked Health Registries.

Purpose: Pregnancies ending before gestational week 12 are common but not notified to the Medical Birth Registry of Norway. Our goal was to develop an algorithm that more completely detects and dates all possible pregnancy outcomes (i.e.

Digital devices for heart rhythm monitoring in atrial fibrillation patients scheduled for elective electrical cardioversion.

Introduction And Objectives: Management in recent-onset atrial fibrillation (AF) is to achieve sinus rhythm (SR) by cardioversion (CV). However, frequently SR is spontaneously restored, making scheduled admission unnecessary and causing misutilization of healthcare resources. Emerging medical technology allows accurate heart rhythm monitoring.