No clear evidence on the clinical performance of different removable prosthetic options in partially edentulous patients.

Data sourcesMedline/PubMed, Embase, BIOSIS/Ovid, SciSearch/DIMDI, Cochrane library, FIZ Technik Web and hand searches of the journals; Clinical Oral Investigations, International Journal of Prosthodontics, Journal of Prosthetic Dentistry, Deutsche Zahnärztliche Zeitschrift, Swiss Dental Journal, Journal of Dentistry and the Journal of Dental Research.Study selectionRandomised controlled trials, prospective and retrospective studies on survival rates of removable dental prostheses in the moderately reduced dentition with at least 15 participants having an observation period of at least two years, and a dropout rate of less than 25% were considered.Data extraction and synthesisTwo reviewers abstracted data.

Novel 2-Thioxanthine and Dipyrimidopyridine Derivatives: Synthesis and Antimicrobial Activity.

Several fused imidazolopyrimidines were synthesized starting from 6-amino-1-methyl-2-thiouracil (1) followed by nitrosation, reduction and condensation with different aromatic aldehydes to give Schiff's base. The dehydrocyclization of Schiff's bases using iodine/DMF gave Compounds 5a-g. The methylation of 5a-g using a simple alkylating agent as dimethyl sulfate ((CH₃)₂SO₄) gave either monoalkylated imidazolopyrimidine 6a-g at room temperature or dialkylated derivatives 7a-g on heating 6a-g with ((CH₃)₂SO₄).

The role of procalcitonin as a guide for the diagnosis, prognosis, and decision of antibiotic therapy for lower respiratory tract infections.

Objectives: To assess the value of PCT as a rapid and sensitive marker for diagnosis, prognosis, and therapy of lower respiratory tract bacterial infections necessitating antimicrobial treatment and comparing this marker with other markers of infections including C-reactive protein (CRP) and total white-blood cell counts (WBCs).

Patients And Methods: Sixty Patients were enrolled in the study, they were subjected to complete history taking, physical examination, laboratory investigations including complete blood count, blood gases, blood chemistry, bacteriological culture for sputum and blood, serology for atypicals, and PCR for respiratory viruses, serum C-reactive protein (CRP) and PCT levels were measured. The patients were divided into two groups, group 1 included 26 patients who were culture negative for bacterial infection and group 2 included 34 patients who were culture positive.