Nonpenetrating deep sclerectomy versus trabeculectomy in bilateral primary open-angle glaucoma.

Objective: To establish the efficacy and safety of nonpenetrating deep sclerectomy versus trabeculectomy in primary open-angle glaucoma.

Design: Prospective randomized trial.

Participants: Thirty-nine patients (78 eyes) with bilateral primary open angle glaucoma were included in the study.

Simultaneous subconjunctival and subscleral mitomycin-C application in trabeculectomy.

Objective: To establish the efficacy and safety of simultaneous subconjunctival and subscleral application of mitomycin-C in trabeculectomy.

Design: A prospective, randomized study.

Participants: Sixty-eight patients (68 eyes) with refractory glaucomas were included in the study.

Phacotrabeculectomy versus two-stage operation: a matched study.

Background And Objective: To evaluate the efficacy and safety of phacoemulsification and foldable intraocular lens, combined with trabeculectomy (phacotrabeculectomy) in patients with coexisting cataract and glaucoma.

Patients And Methods: A total of 53 consecutive eyes which underwent phacotrabeculectomy and posterior chamber intraocular lens (PCIOL) were matched and compared with 53 eyes that had trabeculectomy followed by phacoemulsification and posterior chamber intraocular lens (mean interval 3.2 month).

Fornix-based versus limbal-based conjunctival flaps in initial trabeculectomy with postoperative 5-fluorouracil: four-year follow-up findings.

Purpose: To evaluate the safety and efficacy of fornix-based conjunctival flap versus limbal-based flap in initial trabeculectomy with postoperative 5-fluorouracil.

Methods: 29 patients (58 eyes) with bilateral primary open-angle glaucoma (POAG) were included in the study. Patients were randomly assigned to have a fornix-based conjunctival flap in one eye and a limbal-based flap in the other, followed by subconjunctival injection of 5-fluorouracil.

Randomized bilateral comparison of excimer laser in situ keratomileusis and photorefractive keratectomy for 2.50 to 8.00 diopters of myopia.

Objective: To compare effectiveness, safety, and stability of excimer laser in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK) for low-to-moderate myopia.

Design: Prospective, randomized, bilateral study.

Participants: Thirty-three patients with a manifest refraction of -2.

One-site versus 2-site phacotrabeculectomy: a randomized study.

Purpose: To compare 1-site and 2-site combined phacoemulsification with foldable intraocular lens (IOL) implantation and trabeculectomy.

Setting: El-Maghraby Eye Hospital, Jeddah, Saudi Arabia.

Methods: Seventy-six eyes with coexisting cataract and glaucoma were randomly assigned to have a mitomycin-C trabeculectomy in a superior quadrant combined with phacoemulsification and foldable IOL implantation through the same incision (1-site group) or a separate, temporal, clear corneal incision (2-site group).

The contribution of phacoemulsification to combined cataract and glaucoma surgery.

The refinements of small incision cataract surgery by phacoemulsification with foldable intraocular lens implantation and the pharmacologic modulation of wound healing have brought new options for the combined procedure. Phacoemulsification combined with filtering surgery has the potential advantage of requiring a smaller conjunctival and scleral incision, which may reduce inflammation and bleb scarring with the possibility of enhanced bleb formation and long-term intraocular pressure control. The smaller phacoemulsification incision also helps to reduce postoperative astigmatism and improve visual results.

Lens capsule inclusion in trabeculectomy with cataract extraction.

Purpose: To deliberately include a flap of anterior lens capsule in the trabeculectomy site to determine whether it aids filtration in a glaucoma bleb.

Setting: El-Maghraby Eye Hospital, Jeddah, Saudi Arabia.

Methods: The study comprised 23 consecutive patients (25 eyes) with dense cataract and uncontrolled glaucoma despite maximum medical therapy.

Increased corneal scarring after phototherapeutic keratectomy in Fuchs' corneal dystrophy.

Purpose: A 63-year-old female with Fuchs' endothelial corneal dystrophy, stromal edema and subepithelial scarring was inappropriately treated with phototherapeutic keratectomy, leading to a central focal circular corneal scar and decreased visual acuity that required penetrating keratoplasty.

Method: The host corneal button was bisected and fixed in 10% formaldehyde and in glutaraldehyde immediately after its removal.

Results: Light microscopy demonstrated a central area of absent Bowman's layer with a thin layer of subepithelial fibrosis, stromal corneal edema, and thickened Descemet's membrane.

Excimer laser phototherapeutic keratectomy before cataract extraction and intraocular lens implantation.

Purpose: To determine whether sequential excimer laser phototherapeutic keratectomy (PTK) followed by cataract extraction and intraocular lens (IOL) implantation with power calculation based on the new corneal curvature is effective in managing superficial corneal disease.

Methods: Of a consecutive series of 18 eyes of 16 patients who received PTK, extracapsular cataract extraction, and posterior chamber IOL insertion, twelve eyes had spheroidal degeneration and six eyes, calcific band keratopathy. The PTK was done with either a Summit ExciMed laser or a Visx 20/20 laser using a 5.

Excimer laser in situ keratomileusis under a corneal flap for myopia of 2 to 20 diopters.

Purpose: We studied the efficacy and safety of a recent technique of keratomileusis for myopia, excimer laser in situ keratomileusis.

Methods: We studied retrospectively 88 eyes of 63 patients who received excimer laser in situ keratomileusis with the Chiron Automated Corneal Shaper and the Summit OmniMed laser under a hinged corneal flap without sutures.

Results: Mean follow-up was 5.

Efficacy and safety of excimer laser photorefractive keratectomy and radial keratotomy for bilateral myopia.

Purpose: To compare the safety and efficacy of radial keratotomy (RK) and photorefractive keratectomy (PRK) to correct myopia.

Methods: In this randomized, prospective, parallel-group study, 33 patients with bilateral myopia of 1.00 to 5.

Automated in situ keratomileusis for myopia.

Background: In situ keratomileusis is a rapidly changing refractive corneal surgical procedure for the correction of myopia. We report here the results of a retrospective study of in situ keratomileusis with the refractive cut made with a microkeratome. The technique represents an intermediate stage of development that used a sutured corneal disc, an early automated microkeratome, and no reoperations for residual refractive error.

Regional variation in corneal topography and wound healing following photorefractive keratectomy.

Background: After excimer laser photorefractive keratectomy, corneal epithelial and anterior stromal wound healing may produce corneal haze and variability in refractive results among patients and eyes.

Methods: We report a retrospective study of 17 selected eyes that received excimer laser photorefractive keratectomy with one of three brands of laser and that exhibited regional variations in corneal wound healing as observed with slit-lamp microscopy and videokeratography (Tomey TMS) within the ablation zone.

Results: All 17 eyes were selected to show that the clear areas in the ablation zone corresponded with flat zones on the videokeratographs and the areas of subepithelial haze corresponded with steeper zones.

Climatic proteoglycan stromal keratopathy, a new corneal degeneration.

Purpose: To characterize a previously undescribed corneal disorder, climatic proteoglycan stromal keratopathy.

Methods: We prospectively characterized the disorder in 58 eyes of 29 patients (ages 41 to 84 years) at the El Maghraby Eye Hospital, Jeddah Saudi Arabia. Light and transmission electron microscopy were performed on six corneal specimens.

Molteno implant versus trabeculectomy with adjunctive intreoperative mitomycin-C in high-risk glaucoma patients.

Purpose: The Molteno implant is one of the most widely used drainage devices for the management of complicated glaucoma. Antiproliferative agents such as mitomycin-C (MMC) have markedly improved the outcome of glaucoma filtering surgery. This case control study compares the results of these two techniques in the management of high-risk glaucoma patients.

Excimer laser in-situ keratomileusis (LASIK) under a corneal flap for myopia of 2 to 20 D.

Background: We report the results of a recent technique of keratomileusis for myopia: excimer laser in-situ keratomileusis (LASIK).

Methods: We studied retrospectively 88 eyes of 63 patients that received LASIK with the Chiron Automated Corneal Shaper and the Summit OmniMed excimer laser under a hinged corneal flap without sutures.

Results: Mean follow-up was 5.

Posterior chamber lens implantation for primary repair of corneal lacerations and traumatic cataracts in children.

Children older than 3 years of age rarely tolerate contact lenses for unilateral surgical aphakia. This problem is even more pronounced following repair of corneal lacerations or perforations that are associated with traumatic cataracts. Even if surgery is successful, such eyes are functionally doomed because of deep anisometropic amblyopia.

Cryolathe keratomileusis for correction of myopia of 4.00 to 8.00 diopters.

Background: During the last decade, new refractive surgery procedures have been introduced; older techniques have been modified or even abandoned. Cryolathe myopic keratomileusis has been in clinical use for approximately 30 years. In this retrospective study, we present our experience in applying this technique for the correction of 4.

Effect of incision size on early postoperative visual rehabilitation after cataract surgery and intraocular lens implantation.

One hundred fifty-one unilateral cataract patients were randomly assigned to receive either a one-piece Staar AA-4203 silicone intraocular lens inserted through a 3.5 mm incision, an loptex 5 mm x 6 mm oval optic lens inserted through a 5.5 mm incision, or an AMO three-piece modified C-loop 6.

Subepithelial reticular cicatrization following radial keratotomy in a patient with inactive trachoma.

Background: Opacification of the clear optical zone following radial keratotomy has not been observed before.

Methods And Results: The authors noted the appearance of subepithelial dense white reticular cicatrization in the central area following radial keratotomy in a patient with inactive trachoma and clear cornea. The corneal changes resulted in regression of the surgical effect and decrease in visual acuity.

Multifocal versus monofocal intraocular lenses. Visual and refractive comparisons.

In a unilateral prospective clinical trial, 77 cases were randomized to receive a 3M multifocal IOL or a conventional monofocal implant. Multifocal cases had better uncorrected near vision than monofocal cases at the two to four month visit. Thirty percent of the multifocal cases had near acuity J1, while only 4% of the monofocal cases had that acuity.

Dissolution of intraocular fibrinous exudate by streptokinase.

In a prospective, open, pilot study, the authors evaluated the effects of intraocular injection of streptokinase on intraocular fibrin. The study was composed of nine patients in whom fibrinous exudate developed after pars plana vitrectomy. There were seven male and two female patients with a mean age of 44 years (range, 27 to 65 years).

Nuclear sclerotic cataract after vitrectomy for idiopathic epiretinal membranes causing macular pucker.

We evaluated the occurrence or progression of nuclear sclerosis of the crystalline lens in 100 eyes after vitrectomy for removal of idiopathic epiretinal membranes causing macular pucker. The follow-up period ranged from six to 99 months (average, 29 months). Visually significant nuclear sclerosis was present preoperatively in three of the operated on eyes and four of the fellow eyes.