Phytochemical profiling and fractionation of extract versus silver nanoparticle-modified extract: assessment of photoprotective, anti-hemolytic, antibacterial, and anti-inflammatory properties.

Introduction: This study investigates the synthesis of silver nanoparticles (Ag NPs) using Helianthemum lippii extract and evaluates their photoprotective, anti-hemolytic, antibacterial, and anti-inflammatory properties compared to various extract fractions, including total aqueous extract (AE), flavonoid monoglycosides (FMG), flavonoid diglycosides/triglycosides (FDG/FTG), tannins (TN), and anthocyanins (AC). Helianthemum lippii is rich in bioactive compounds such as caffeic acid, p-coumaric acid, and gallic acid, known for their therapeutic potential. This study aims to determine whether embedding these phytochemicals into Ag NPs enhances their biomedical applications compared to the natural extract fractions.

Evaluation of Dermal Wound Healing Potential: Phytochemical Characterization, Anti-Inflammatory, Antioxidant, and Antimicrobial Activities of Euphorbia guyoniana Boiss. & Reut. Latex.

This study investigates the wound-healing potential of Euphorbia guyoniana latex (EGL) in male Wistar rats, along with its biochemical composition and biological activities. Phytochemical analysis identified moderate levels of phenolics, flavonoids, and tannins, with HPLC revealing five phenolic compounds. EGL demonstrated strong antioxidant activity in DPPH assays, surpassing ascorbic acid in protecting red blood cells.

Assessment of Artemisia Campestris L. Leaf Extract Effects on Polycystic Ovarian Syndrome in Rats, Antioxidant and α-Amylase Inhibition Activities.

Polycystic Ovarian Syndrome (PCOS) is characterized by metabolic and reproductive dysfunction, often associated with elevated oxidative stress markers in the bloodstream. This study examines the potential antioxidant properties and α-amylase inhibitory activity of Artemisia campestris leaves extract (Artemisia campestris L) and its effects on rats with induced PCOS. Estradiol valerate was administered to ten mature Wistar rats to induce PCOS, while a control group consisted of five mature Wistar rats.

Disease activity score for still's disease.

Objective: To develop the Still's Disease Activity Score (SDAS).

Methods: We used data from the prospective adult-onset Still's disease cohort study and evaluated the disease activity. An expert group selected the most frequent, reproducible, and objective variables significantly modified in statistical analysis when comparing patients in the active group and in the remission group.

Therapeutic Efficacy of Extract and Silver Nanoparticles Synthesized from the Extract against Cadmium-Induced Renal Nephrotoxicity in Wistar Rats.

This study explored the therapeutic efficacy of and silver nanoparticles (Ag NPs) synthesized using a extract to alleviate cadmium-induced nephrotoxicity in Wistar rats. Sub-acute toxicity assessments of (100 mg/kg, 1000 mg/kg, and 4000 mg/kg) and Ag NPs (2 mg/kg and 10 mg/kg) did not find any significant difference, compared with untreated control rats ( = 3 animals/group). Then, the adult Wistar rats were divided into one control (untreated/unexposed) and six experimental groups ( = 5/group): Ag NPs alone, alone, exposure to 50 mg/kg CdCl in drinking water for 35 days, exposure to CdCl for 35 days followed by treatment with 0.

Flow cytometry-based diagnostic approach for inborn errors of immunity: experience from Algeria.

Purpose: In this study, we retrospectively reviewed the use of flow cytometry (FCM) in the diagnosis of inborn errors of immunity (IEIs) at a single center in Algeria. Sharing insights into our practical experience, we present FCM based diagnostic approaches adapted to different clinical scenarios.

Methods: Between May 2017 and February 2024, pediatric and adult patients presenting with clinical features suggestive of immunodeficiency were subjected to FCM evaluation, including lymphocyte subset analysis, detection of specific surface or intracellular proteins, and functional analysis of immune cells.

Encapsulation of sunflower and flaxseed oils using Opuntia (Cactaceae) mucilage as a core-shell material through coacervation methods: A study on formulation, characterization, and in vitro digestion.

Sunflower oil (SFO) and Flaxseed oil (FSO) were microencapsulated using simple and complex coacervation techniques with Opuntia (Cactaceae) mucilage (Mu) and with a combination of Mu with chitosan (Chit). The encapsulation efficiency (EE) of SFO and FSO in emulsions using Mu/Chit shells was 96.7% and 97.

Therapeutic potential of silver nanoparticles from extract for mitigating cadmium-induced hepatotoxicity: liver function parameters, oxidative stress, and histopathology in wistar rats.

This study explores the therapeutic potential of silver nanoparticles (Ag NPs) synthesized using a extract in mitigating cadmium-induced hepatotoxicity in Wistar rats. Given the increasing environmental and health concerns associated with cadmium exposure, novel and eco-friendly therapeutic strategies are essential. Ag NPs were characterized using X-ray diffraction, UV-Vis spectrometry, and energy-dispersive X-ray spectroscopy with scanning electron microscopy, confirming their formation with a cubic crystal structure and particle sizes ranging from 4.

Nanostructured Mn@NiO composite for addressing multi-pollutant challenges in petroleum-contaminated water.

Efficient catalysts play a pivotal role in advancing eco-friendly water treatment strategies, particularly in the removal of diverse organic contaminants found in water-petroleum sources. This study addresses the multifaceted challenges posed by contaminants, encompassing a spectrum of heavy metals such as As, Cd, Cr, Mn, Mo, Ni, Pb, Sb, Se, and Zn alongside pollutants like oily water (OIW), total suspended solids (TSS), chemical oxygen demand (COD), dyes, and pharmaceuticals, posing threats to both aquatic and terrestrial ecosystems. Herein, we present the synthesis of biogenically derived Mn@NiO nanocomposite (NC) photocatalysts, a sustainable methodology employing an aqueous Rosmarinus officinalis L.

Potential Hepatoprotective Effect of Matricaria Pubescens on High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Rats.

This study aimed to identify the phytochemical compounds of Matricaria pubescens by LC-MS/MS and evaluate the potential protective effect of its supplementation in high-fat diet (HFD)-induced non-alcoholic fatty liver disease (NAFLD) in adult rats through modulation of oxidative stress and histopathological changes. Twenty-four male rats were randomly divided into four groups. The first group served as control and received the standard diet.

Establishment of biochemical and hematological profiles of dromedary camel (Camelus dromedarius) under extensive and intensive production systems.

In Algeria, camel husbandry is undergoing a shift from a traditional extensive system to one more intensive. Such a move in the production system of the dromedary camel should be well investigated in terms of animal welfare, health, and production status. The main objective of this study was to define and evaluate the effects of production systems on physiological responses (hematological and biochemical parameters) in Sahraoui dromedary camels to understand possible changes caused by intensive livestock farming.

Efficient treatment of oily wastewater, antibacterial activity, and photodegradation of organic dyes using biosynthesized Ag@FeO nanocomposite.

A significant waste (e.g., high oil content and pollutants such as heavy metals, dyes, and microbial contaminants) in water is generated during crude oil extraction and industrial processes, which poses environmental challenges.

Phytochemical profiling of Delile by LC-HR/MS and investigation of the antioxidant, anti-inflammatory, cytotoxic, antibacterial and anti-SARS-CoV-2 activities.

This study aimed to investigate the phytochemical composition and biological activity of Delile. (Amaranthaceae), a medicinal plant. The study evaluated the antioxidant potential of the crude extract and five fractions of using DPPH, ABTS+, CUPRAC, and metal chelating assays.

Increased risk of brucellosis misdiagnosis in regions that lose their endemicity.

Over the last decades, the epidemiology of human brucellosis globally has been subjected to significant changes, with the eradication of many existing endemic hot spots. This paper describes three cases with initial misdiagnosis of brucellosis that were managed during 2011-2017 in Republic of North Macedonia, country that until recently has been declared as endemic region. In spite of the fever, constitutional symptoms, focal disease (spondylitis, pneumonia and orchitis) and previous contact with domestic animals, brucellosis was not initially recognized, and patients were inadequately managed.

Biochemical Profile and In Vitro Therapeutic Properties of Two Euhalophytes, Pall. and (L.) Forske., Grown in the Sabkha Ecosystem in the Algerian Sahara.

This study reports the biochemical profile and in vitro biological activities of the aerial part of two shrubs: and , a halophytes species native to saline habitats. The biomass was evaluated by determining its physiological properties and approximate composition. Hydro-methanolic extracts from and have been investigated for the inhibition of bacterial growth, the protection of proteins (albumin) from denaturation, and cytotoxicity to hepatocellular carcinomas (Huh-7 and HepG2).

Proposal of a new diagnostic algorithm for adult-onset Still's disease.

Objective: This study was performed to develop a new diagnostic algorithm for adult-onset Still's disease (AOSD).

Methods: We conducted a multicenter prospective nationwide case-control study in tertiary Internal Medicine, Rheumatology, and Infectious Diseases departments, to include successively patients with suspected AOSD based on the presence of two or more major criteria of Yamaguchi and/or Fautrel classifications. Patients were classified as AOSD or controls according to a predefined procedure.

Incidence rates of dysentery among humans in Lemghaier province, Algeria.

Introduction: Dysentery is an infectious clinical syndrome which can cause high morbidity and mortality, especially in developing countries. This research highlights the epidemiological features of dysentery in Lemghaier province, Algeria.

Methods: A retrospective study of the incidence rates of dysentery in Lemghaier province, Algeria and overall for the whole country for the period from January 2001 to December 2018 was carried out.

Rule-Based Arabic Sentiment Analysis using Binary Equilibrium Optimization Algorithm.

With the development of websites and social networks, Internet users generate a massive amount of comments and information on the Web. Sentiment analysis, also called opinion mining, offers an opportunity to mine the people's sentiments and emotions from the textual comments. In the last decade, sentiment analysis has been applied in research areas such as recommendation and support systems and has become an area of interest for many researchers.

Validation of the neutrophil-to-lymphocyte ratio as a new simple biomarker of adult onset Still's disease: A STROBE-Compliant prospective observational study.

This study was performed to investigate the role of neutrophil-to-lymphocyte ratio (NLR) in the diagnosis of adult onset Still disease (AOSD) and its performance to improve the sensitivity of the classifications criteria (Yamaguchi and Fautrel Classifications). We conducted a multicenter prospective nationwide case-control study in Internal medicine, Rheumatology and Infectious disease departments, to include successively patients with suspected AOSD (2 or more major criteria of Yamaguchi or Fautrel classifications). All clinical and biological features were collected in a consensual and standardized clinical assessment at baseline and during follow-up.

Energy, exergy, and economic analysis of solar still using coal cylinder fins: an experimental study.

The phenomenon of drinking water scarcity has turned into the foremost issue that the world's populace is facing today. The Algerian desert regions, including the El Oued region (southeastern Algeria), also suffer from drinking water shortages, despite the presence of huge quantities of underground salty water. Solar distillation is among the easy and cheap solutions to solve this problem because this method relies on renewable energy (solar energy) as a key factor in providing drinking water from saltwater.

Inborn Errors of Immunity in Algerian Children and Adults: A Single-Center Experience Over a Period of 13 Years (2008-2021).

Background: Inborn errors of immunity (IEI) predispose patients to various infectious and non-infectious complications. Thanks to the development and expanding use of flow cytometry and increased awareness, the diagnostic rate of IEI has markedly increased in Algeria the last decade.

Aim: This study aimed to describe a large cohort of Algerian patients with probable IEI and to determine their clinical characteristics and outcomes.