137 results match your criteria: "El Ayachi Hospital[Affiliation]"

Objective: The objective of this study was to develop the first Moroccan recommendations concerning nutrition in patients with osteosarcopenia.

Material And Methods: A steering committee consisting of rheumatologists and nutritionists drafted the initial version of the recommendations in light of the literature review and the recommendations of international societies. The draft was reviewed by a reading committee of 13 experts to approve the final version.

View Article and Find Full Text PDF

Background and objective Secukinumab (SECU) is a biologic disease-modifying antirheumatic drug (bDMARD) that has demonstrated effectiveness against axial spondyloarthritis (ax-SpA). However, in clinical practice, secukinumab is most commonly used as a second-line treatment after failure of or intolerance to tumor necrosis factor inhibitors (TNFi). In this study, we aimed to compare the two-year drug retention between secukinumab and TNFi in biologic-naïve patients with ax-SpA, to estimate the remission/low disease activity (LDA) rates in both groups and assess the safety profiles.

View Article and Find Full Text PDF
Article Synopsis
  • * Data was collected through interviews and patient files, focusing on costs like productivity losses, formal care expenses, and intangible impacts on activities and relationships.
  • * Findings indicate significant financial burdens on patients, with annual costs averaging $2337.73 due to lost wages and notable intangible effects, particularly related to personal relationships and lifestyle changes.
View Article and Find Full Text PDF

Introduction Fibromyalgia (FM) is characterized by widespread pain and fatigue, accompanied by symptoms such as decreased concentration, autonomic dysfunction, and abdominal pain. It can be either primary or secondary, notably to rheumatoid arthritis (RA). The Fibromyalgia Assessment Screening Tools (FAST 4), derived from the Multidimensional Health Assessment Questionnaire (MDHAQ), is a composite tool allowing for the rapid screening of FM.

View Article and Find Full Text PDF

Background: Tofacitinib is an oral Janus kinase inhibitor for treatment of ankylosing spondylitis (AS). Time to improvement in core domains of AS was estimated in tofacitinib-treated patients with AS.

Methods: This post hoc analysis used phase 3 trial data from patients with AS receiving tofacitinib 5 mg twice daily or placebo to week (W)16; all patients received open-label tofacitinib W16-48.

View Article and Find Full Text PDF
Article Synopsis
  • * The study involved 554 patients from 13 Arab countries, validating the Arabic version of the PsAID-12 with strong internal consistency (Cronbach's α = 0.95) and substantial test-retest reliability (ICC 0.90).
  • * Key factors linked to higher PsAID-12 scores included disability, depression, widespread pain, and disease activity, highlighting pain and fatigue as critical concerns for patients with psoriatic arthritis.
View Article and Find Full Text PDF

In 2017, the Moroccan Society of Rheumatology (SMR) issued guidelines for the treatment of severe ankylosing spondylitis. The emergence of new therapeutic classes, the update of international guidelines for axial SpA and psoriatic arthritis, and the diagnostic and therapeutic challenges encountered by rheumatologists has led to the development of recent SMR guidelines for the management of SpA patients. A group-work included rheumatologists, specialists in physical medicine and rehabilitation, and epidemiologists from various sectors was tasked with writing these recommendations based on a literature review, then adapting them to the national context.

View Article and Find Full Text PDF

The advent of new therapeutic classes and the updating of international recommendations have justified the development of recent recommendations by the Moroccan Society of Rheumatology. Methods Guidelines were drafted by a core steering committee after performing a literature search. A multidisciplinary task force, including three fellows, eleven rheumatologists, a specialist in physical medicine and rehabilitation, an epidemiologist from hospital-university, hospital and liberal sectors and one patient assessed the Best Practice Guidelines using 2 rounds of anonymous online voting by modified Delphi process.

View Article and Find Full Text PDF
Article Synopsis
  • The study investigated characteristics of late-onset spondyloarthritis (SpA) in patients over 45 years old, comparing them to those with early-onset SpA aged 45 or younger.
  • Data were collected from the Moroccan registry of biological therapies, involving 194 patients, with 31 classified as having late-onset SpA.
  • Key findings included that late-onset SpA patients had significantly more tender and swollen joints, higher rates of depression and fibromyalgia, but lower occurrences of coxitis compared to early-onset patients.
View Article and Find Full Text PDF

Objectives: To describe and analyse the prevalence of extra-articular manifestations (EAMs) including acute anterior uveitis (AAU), psoriasis and inflammatory bowel disease (IBD) in patients with ankylosing spondylitis (AS) in the Moroccan registry of biological therapies in rheumatic diseases RBSMR (Registre des Biothérapies de la Société Marocaine de Rhumatologie).

Methods: A cross-sectional, multicentre and analytical study based on the RBSMR database, which included 170 AS. Incidence rates for the development of AAU, psoriasis and IBD were calculated, and risk factors were analysed.

View Article and Find Full Text PDF

Despite of the availability of several effective bDMARDs, a significant proportion of rheumatoid arthritis (RA) and ankylosing spondylitis (AS) patients discontinued bDMARDs. The aims of this study were to analyze causes of bDMARDs discontinuation in RA and AS included in the Moroccan registry RBSMR. A historical prospective multicenter cohort study based on the RBSMR database at 12 months of follow-up, which included 225 RA and 170 AS.

View Article and Find Full Text PDF

Objectives: The aim of this study was to determine the therapeutic maintenance level of methotrexate for rheumatoid arthritis patients enrolled in the Moroccan biotherapy registry and to identify predictive factors for discontinuing MTX treatment.

Methods: A cross-sectional study was conducted using the baseline data of the Moroccan biotherapy registry for RBSMR (a multicentric study that aims to evaluate tolerance of biological therapy on patients affected with rheumatic diseases). Demographics and disease features were compared using descriptive statistics.

View Article and Find Full Text PDF

Background: The aim of this study was to evaluate the prevalence of active tuberculosis (TB) infection in Moroccan patients with rheumatic diseases under biologic therapy, and to describe the demographic characteristics of these patients as well as to explore potential risk factors.

Methods: This 14-year nationally representative multicenter study enrolled Moroccan patients with rheumatic diseases who had been treated with biologic therapy. Patient medical records were reviewed retrospectively for demographic characteristics, underlying rheumatic diseases, associated comorbidities, and TB-related data.

View Article and Find Full Text PDF

Background: Kinesiotaping (KT) is widely used in several musculoskeletal disorders particularly in shoulder pain. However, literature shows controversial results regarding the effect of KT on shoulder pathology. The aim of this study was to assess the clinical effects of KT in the short term on rotator cuff tendinopathy (RCT).

View Article and Find Full Text PDF

Oral Hygiene Status in Rheumatoid Arthritis Patients and Related Factors.

Mediterr J Rheumatol

September 2021

Rheumatology B Department, El Ayachi Hospital, Faculty of Medicine and Pharmacy of Rabat, Mohammed V University, Rabat, Morocco.

Objectives: To evaluate oral hygiene status in Rheumatoid arthritis (RA) patients, to analyse possible related factors, and to investigate the role of the rheumatologist in information about importance of adequate oral hygiene status in RA patients.

Methods: A cross-sectional study that included 100 consecutive RA patients (89% female, mean age 46.7 ± 11.

View Article and Find Full Text PDF

Ultrasonography of Shoulder in Rheumatoid Arthritis: A Reliability Exercise Using Consensual Definitions among Maghrebian Rheumatologists.

Ultrasound Med Biol

December 2021

Comité d'Experts Maghrébins en Imagerie Rhumatologique, Rabat, Morocco; Rheumatology Department, Mohamed V University, El Ayachi Hospital, Rabat-Salé, Morocco.

The shoulder may be affected in a large portion of patients with rheumatoid arthritis (RA) worldwide. However, this joint does not receive the attention required during follow-up. Indeed, although numerous clinical tests for diagnosis of a painful shoulder are available, differentiating articular from peri-articular lesions may be difficult in daily practice.

View Article and Find Full Text PDF
Article Synopsis
  • Before starting biotherapy for rheumatic diseases, patients should be screened for latent tuberculosis infection (LTBI), and a study was conducted to assess the prevalence of LTBI in Moroccan patients with rheumatoid arthritis (RA) and spondyloarthritis (SpA).
  • The study included 259 patients (94 with RA and 165 with SpA) and found an overall LTBI prevalence of 21.6%, with higher rates in SpA (24.8%) compared to RA (15.9%).
  • Demographic and clinical characteristics showed no significant differences between LTBI-positive and negative patients, indicating that being in a TB-endemic country like Morocco presents a notable risk for both RA and SpA patients.
View Article and Find Full Text PDF

Introduction: the aim of our study is to determine, from data of the Moroccan register of biotherapies, the factors influencing the choice of the first prescribed biological treatment.

Methods: cross-sectional multicenter study including rheumatoid arthritis patients who were initiated the first biological treatment either: Rituximab, an anti-TNF, or Tocilizumab. The determinants related to the patient and disease have been gathered.

View Article and Find Full Text PDF

The aim of the study was to estimate the annual direct costs of biological therapies in rheumatoid arthritis (RA), and to establish possible factors associated with those costs. The main data source was the Moroccan registry of biological therapies in rheumatic diseases (RBSMR Registry). We included patients with available 1-year data.

View Article and Find Full Text PDF
Article Synopsis
  • The study aims to assess how rheumatology services in Africa have changed due to the COVID-19 pandemic, using an online survey of rheumatologists across the continent.
  • A total of 554 responses were collected from 20 African countries, revealing that many rheumatologists shifted toward virtual consultations while some still held face-to-face appointments with protective measures.
  • The findings highlight significant regional differences in the adaptation to the pandemic, including the creation of national guidelines and the availability of COVID-19 registries for rheumatology.
View Article and Find Full Text PDF