933 results match your criteria: "Edward S. Harkness Eye Institute[Affiliation]"
Indian J Ophthalmol
January 2025
Shri Bhagwan Mahavir Vitreoretinal Services, Sankara Nethralaya, Tamil Nadu, India.
Transl Vis Sci Technol
December 2024
Bernard and Shirlee Brown Glaucoma Research Laboratory, Department of Ophthalmology, Edward S. Harkness Eye Institute, Columbia University Irving Medical Center, New York, NY, USA.
Purpose: To develop and test a novel optical coherence tomography (OCT) metric for the detection of glaucoma based on a logistic regression model (LRM) and known patterns of glaucomatous damage.
Methods: The six variables of the LRM were based on characteristic patterns of damage seen on the OCT thickness maps of the ganglion cell layer plus inner plexiform layer (GCL+) and retinal nerve fiber layer (RNFL). Two cohorts were used to develop the LRM.
Br J Ophthalmol
December 2024
Viterbi Family Department of Ophthalmology, University of California San Diego, La Jolla, California, USA
Background: To evaluate the impact of testing frequency on the time required to detect statistically significant glaucoma progression for ganglion cell complex (GCC) with optical coherence tomography (OCT).
Materials And Methods: From multicentre glaucoma registries, 332 eyes of 201 glaucoma patients were enrolled over an average of 4.4 years.
Ophthalmic Plast Reconstr Surg
December 2024
Department of Ophthalmology, Edward S. Harkness Eye Institute, Columbia University Irving Medical Center, New York, New York, U.S.A.
Purpose: Current treatment approaches aimed at resolving a chalazion vary greatly among practice settings and practitioners. Our objective is to provide a review of existing literature on treatment modalities aimed at resolving a chalazion.
Methods: We conducted a review of existing peer-reviewed publications that described treatment methods aimed at resolving chalazia in patients of any age.
Curr Opin Neurol
February 2025
Edward S. Harkness Eye Institute, Columbia University, New York, New York, USA.
Purpose Of Review: An overview of two ocular diseases, which significantly impact quality of life: thyroid eye disease (TED) and ocular myasthenia gravis (OMG). Additionally, we describe the clinical challenge when they occur simultaneously. We will describe the pathophysiology of both conditions, the currently available diagnostic tools, and the therapies available.
View Article and Find Full Text PDFOphthalmic Plast Reconstr Surg
November 2024
Department of Ophthalmology, Edward S. Harkness Eye Institute, Columbia University, New York, NY, U.S.A.
We report the first case of generalized lipodystrophy with orbital inflammatory symptoms. A 6-year-old female with hypothyroidism who developed hepatosplenomegaly, lymphadenopathy, and progressive loss of subcutaneous fat. Following flu vaccination, she developed orbital inflammatory symptoms.
View Article and Find Full Text PDFJAMA Ophthalmol
November 2024
Viterbi Family Department of Ophthalmology, Hamilton Glaucoma Center, Shiley Eye Institute, University of California, San Diego, La Jolla.
Cornea
November 2024
Department of Ophthalmology, Edward S. Harkness Eye Institute, Columbia University Irving Medical Center, New York, NY.
Purpose: To identify sociodemographic factors as predictors of keratoconus severity, progression, disease outcomes, and appropriate management in a tertiary care ophthalmology institute in the New York City metropolitan area.
Methods: This is a retrospective chart review. Patients with keratoconus presenting at a tertiary eye institute in an urban setting seen between 2015 and 2022 were included.
Am J Ophthalmol
October 2023
Department of Ophthalmology and Visual Sciences, The University of Alabama at Birmingham, Birmingham, USA. Electronic address:
Purpose: To evaluate the diagnostic accuracy of retinal nerve fiber layer thickness (RNFLT) by spectral-domain optical coherence tomography (OCT) in primary open-angle glaucoma (POAG) in eyes of African (AD) and European descent (ED).
Design: Comparative diagnostic accuracy analysis by race.
Participants: 379 healthy eyes (125 AD and 254 ED) and 442 glaucomatous eyes (226 AD and 216 ED) from the Diagnostic Innovations in Glaucoma Study and the African Descent and Glaucoma Evaluation Study.
Retin Cases Brief Rep
October 2024
Edward S Harkness Eye Institute, Columbia University Medical Center/New York Presbyterian, New York, NY.
Purpose: To characterize two cases of focal outer retinal atrophy and hypotony after vitrectomy.
Methods: Retrospective chart review of two patients' records between 2019 and 2023.
Results: Patient 1 underwent vitrectomy, epiretinal membrane peel, and cataract extraction for visually significant macular pucker.
Taiwan J Ophthalmol
September 2024
Shiley Eye Institute and Viterbi Family Department of Ophthalmology, University of California San Diego, La Jolla, California.
The application of artificial intelligence (AI) in ophthalmology has been increasingly explored in the past decade. Numerous studies have shown promising results supporting the utility of AI to improve the management of ophthalmic diseases, and glaucoma is of no exception. Glaucoma is an irreversible vision condition with insidious onset, complex pathophysiology, and chronic treatment.
View Article and Find Full Text PDFTransl Vis Sci Technol
October 2024
Department of Biomedical Engineering, Columbia University, New York, New York, USA.
Br J Ophthalmol
December 2024
Department of Ophthalmology, Chang Gung Memorial Hospital, Linkou Medical Center, Taoyuan, Taiwan
Background/aims: The aims of this study is to evaluate the anatomic, visual outcomes and associated prognostic factors in patients with advanced retinopathy of prematurity (ROP) following vitrectomy.
Methods: A retrospective cohort study of patients with ROP who underwent vitrectomy from 2005 to 2016 was conducted. All the patients had a follow-up period of at least 5 years.
Asia Pac J Ophthalmol (Phila)
October 2024
Retina Division, Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD 21287, USA. Electronic address:
Transl Vis Sci Technol
October 2024
Bernard and Shirlee Brown Glaucoma Research Laboratory, Department of Ophthalmology, Edward S. Harkness Eye Institute, Columbia University Irving Medical Center, New York, NY, USA.
Purpose: To compare an optical coherence tomography (OCT) real-world reference database (RW-RDB) of "healthy" eyes obtained from optometry practices to a commercial reference database (RDB).
Methods: OCT scans from 6804 individuals 18 years and older were sampled from a larger database tested at 10 optometry practices involved in refractive and screening services. Employing a reading center method, OCT scans from both eyes of 4932 (4.
Clin Exp Ophthalmol
September 2024
Department of Ophthalmology, Chang Gung Memorial Hospital, Linkou Medical Center, Taoyuan, Taiwan.
Background: To explore the role of gut microbiota in preterm infants at high risk of developing retinopathy of prematurity (ROP).
Methods: Preterm infants with gestational age (GA) < 32 weeks and/or birth weight (BW) < 1500 g born between 2020 and 2021 were prospectively enrolled. Their faecal samples were collected and analysed at different postnatal ages of life using 16S rRNA gene sequencing on the Miseq platform.
Graefes Arch Clin Exp Ophthalmol
September 2024
Department of Ophthalmology, Vagelos College of Physicians and Surgeons, Edward S. Harkness Eye Institute, Columbia University Irving Medical Center, New York, NY, USA.
Purpose: To assess the value of increased perifoveal retinal vascular tortuosity in optical coherence tomography angiography (OCTA) images as a biomarker of early hypertensive retinopathy and compare its clinical sensitivity and accuracy with traditional morphological changes used for Scheie classification.
Methods: OCTA images of 81 eyes (40 eyes from 20 hypertensive subjects and 41 eyes from 21 control subjects) were obtained retrospectively. Hypertensive retinopathy changes in randomized eyes were graded according to the Scheie classification, and perifoveal vessels were traced in a masked fashion.
Eur J Med Genet
October 2024
Department of Pathology & Cell Biology, Columbia University Irving Medical Center, New York, NY, United States. Electronic address:
TAF1A, a gene encoding a TATA-box binding protein involved in ribosomal RNA synthesis, is a candidate gene for pediatric cardiomyopathy as biallelic TAF1A variants were reported in two families with affected individuals. Here, we report a third family with two siblings who presented with infantile restrictive cardiomyopathy and carried biallelic missense variants in TAF1A (NM_001201536.1:c.
View Article and Find Full Text PDFInt J Mol Sci
August 2024
Department of Ophthalmology, Chang Gung Memorial Hospital, Linkou Medical Center, Taoyuan 33305, Taiwan.
This review explored the role of mitochondria in retinal ganglion cells (RGCs), which are essential for visual processing. Mitochondrial dysfunction is a key factor in the pathogenesis of various vision-related disorders, including glaucoma, hereditary optic neuropathy, and age-related macular degeneration. This review highlighted the critical role of mitochondria in RGCs, which provide metabolic support, regulate cellular health, and respond to cellular stress while also producing reactive oxygen species (ROS) that can damage cellular components.
View Article and Find Full Text PDFJCI Insight
August 2024
Jonas Children's Vision Care, Department of Ophthalmology, Columbia University, New York, New York, USA.
Orbit
August 2024
Department of Ophthalmology, Edward S. Harkness Eye Institute, New York Presbyterian-Columbia University, New York, New York, USA.
We present a novel case of intraosseous venous malformation of the frontal bone with dehiscence of the inner table of the frontal calvarium and extension into the frontal sinus and orbit. This case report discusses the surgical management of this intraosseous lesion achieved with a multidisciplinary approach involving otolaryngology and neurosurgical teams. We also present a review of the literature of the pathophysiology of venous malformations, the imaging modalities that aid in diagnosis of these lesions and the management options.
View Article and Find Full Text PDFJ Glaucoma
August 2024
New York Eye and Ear Infirmary of Mount Sinai, New York, NY.
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View Article and Find Full Text PDFJ Glaucoma
August 2024
Bernard and Shirlee Brown Glaucoma Research Laboratory, Department of Ophthalmology, Edward S. Harkness Eye Institute.
Am J Ophthalmol
January 2025
From the Department of Ophthalmology (P-K.L., W.L., P-Y.S., A-H.K., E.Y-C.K., S.R.L., L.A.J., P-H.L., P-L.W., E.H-H.W., S.H.T., R.A., N-K.W.), Edward S. Harkness Eye Institute, Columbia University, New York, New York, USA; Department of Ophthalmology (E.Y-C.K., L.L., K-J.C., Y-S.H., W-C.W., C-C.L., N-K.W.), Chang Gung Memorial Hospital, Linkou Medical Center, Taiwan; College of Medicine (E.Y-C.K., K-J.C., Y-S.H., W-C.W., C-C.L., N-K.W.), Chang Gung University, Taoyuan, Taiwan; Vagelos College of Physicians and Surgeons (S.H.T., R.A., N-K.W.), Columbia University, New York, New York, USA. Electronic address:
Retina
August 2024
Department of Ophthalmology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.