3,976 results match your criteria: "Eastman Dental Institute & University College London Hospitals[Affiliation]"

The development of dental materials needs to be supported with sound evidence. This in vitro study aimed to measure the fracture toughness of a short fibre-reinforced composite (sFRC), at differing thicknesses. In this study, 2 mm, 3 mm and 4 mm depths of sFRC were prepared.

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Research of Optical Properties and Biocompatibility in Different Zones of Multilayered Translucent Zirconia on Hydrothermal Aging.

Materials (Basel)

October 2024

Department of Prosthodontics, College of Dentistry, Dankook University, 119 Dandae-ro, Cheonan 31116, Republic of Korea.

Objective: We assessed the changes in optical properties and biocompatibility of transition zones in multilayered translucent monolithic zirconia exposed to prolonged hydrothermal aging and compared the results to those with different yttrium oxide contents.

Materials And Methods: Four types of zirconia blocks from IPS e.max ZirCAD were used: 3Y-TZP e.

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Background: Limited access to pediatric oral health care in rural US areas is a substantial dental public health problem. In 2010, the Eastman Institute for Oral Health at the University of Rochester, initiated a synchronous teledentistry program to enhance oral health screenings, treatment planning, and treatment completion for rural pediatric patients who reside in the Western region of New York.

Methods: Data from dental records of all pediatric patients who were participants in the teledentistry program from its inception on April 13, 2010 through December 31, 2022, were reviewed.

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Bioprinting of Aptamer-Based Programmable Bioinks to Modulate Multiscale Microvascular Morphogenesis in 4D.

Adv Healthc Mater

January 2025

Department of Biomechanical Engineering, Technical Medical Centre, University of Twente, Enschede, 7522NB, The Netherlands.

Dynamic growth factor presentation influences how individual endothelial cells assemble into complex vascular networks. Here, programmable bioinks are developed that facilitate dynamic vascular endothelial growth factor (VEGF) presentation to guide vascular morphogenesis within 3D-bioprinted constructs. Aptamer's high affinity is leveraged for rapid VEGF sequestration in spatially confined regions and utilized aptamer-complementary sequence (CS) hybridization to tune VEGF release kinetics temporally, days after bioprinting.

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Objectives: This study aims to assess dental residents' perinatal oral health (POH) knowledge and Regulatory Focus Types' (RFT) impact on their knowledge before and after education.

Materials And Methods: A total of 53 dental residents from upstate New York participated from 2019 to 2021. A validated questionnaire collected demographic data, resident's POH knowledge, RFT, and self-reported burnout levels.

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Background: Oral non-communicable diseases, particularly dental caries and periodontal disease, impose a significant global health burden. The underlying microbial dysbiosis is a prominent factor, driving interest in strategies that promote a balanced oral microbiome. , a gram-positive lactic acid bacterium known for its adaptability, has gained attention for its potential to enhance oral health.

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Skeletal and dental open bite treatment using clear aligners and orthodontic miniscrew-anchored fixed appliances in permanent dentition: A systematic review.

J World Fed Orthod

October 2024

Department of Orthodontics, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan; Department of Biochemistry and Molecular Dentistry, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan. Electronic address:

Background: The objective was to systematically review studies assessing the efficacy of clear aligner therapy (CAT) and miniscrew-anchored fixed appliances (MAFAs) in the correction of skeletal and dental open bite in the permanent dentition.

Methods: A literature search was conducted across different databases, including PubMed, Cochrane Library, Science Direct, Web of Science, Medline, Scopus and Google Scholar, up to April 2024. Studies were chosen based on prespecified inclusion criteria.

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Oral malignant and potentially malignant lesions after allogenic hematopoietic cell transplantation: a 10-year follow-up study.

Bone Marrow Transplant

October 2024

Department of Oral Medicine, Infection, and Immunity - Harvard School of Dental Medicine, Division of Oral Medicine and Dentistry, Brigham and Women's Hospital, Boston, MA, USA.

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Article Synopsis
  • The study aimed to compare patient education materials on cataract surgery created by ChatGPT-4 and Google Bard, using a set of curated FAQs from trusted online resources.
  • Results showed that while Google Bard had a higher readability score, ChatGPT-4 excelled in understandability, particularly in preparation and recovery information.
  • Overall, ChatGPT-4 was found to be more effective in delivering understandable content, but further research with real patient input is needed to ensure relevance to actual patient needs.
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Comparison of Flexural Strength and Wear of Injectable, Flowable and Paste Composite Resins.

Materials (Basel)

September 2024

Department of Prosthodontics, University College London Eastman Dental Institute, Rockefeller Building, 21 University Street, London WC1E 6DE, UK.

(1) Objectives: This study investigated and compared the wear and flexural strength of two highly filled (injectable), one flowable and one paste composite. (2) Methods: Two highly filled flowable composites (G-aenial Universal Injectable and Beautifil Plus F00), a paste composite (Empress Direct) and a conventional flowable (Tetric EvoFlow) were tested. A two-body wear test was carried out using 10 disc-shaped samples from each group, which were subjected to 200,000 wear machine cycles to simulate wear, followed by Scanning Electron Microscope analysis.

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Electrically-stimulated cellular and tissue events are coordinated through ion channel-mediated calcium influx and chromatin modifications across the cytosol-nucleus space.

Biomaterials

March 2025

Institute of Tissue Regeneration Engineering (ITREN), Dankook University, Cheonan, 31116, Republic of Korea; Department of Nanobiomedical Science and BK21 NBM Global Research Center for Regenerative Medicine, Dankook University, Cheonan, 31116, Republic of Korea; Mechanobiology Dental Medicine Research Center, Dankook University, Cheonan, 31116, Republic of Korea; Department of Biomaterials Science, College of Dentistry, Dankook University, Cheonan, 31116, Republic of Korea; Department of Regenerative Dental Medicine, College of Dentistry, Dankook University, Cheonan, 31116, Republic of Korea; Cell & Matter Institute, Dankook University, Cheonan, 31116, Republic of Korea; UCL Eastman-Korea Dental Medicine Innovation Centre, Dankook University, Cheonan, 31116, Republic of Korea. Electronic address:

Electrical stimulation (ES) through biomaterials and devices has been implicated in activating diverse cell behaviors while facilitating tissue healing process. Despite its significance in modulating biological events, the mechanisms governing ES-activated cellular phenomena remain largely elusive. Here, we demonstrated that millisecond-pulsed temporal ES profoundly impacted a spectrum of cellular events across the membrane-cytosol-nuclear space.

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Purpose: Orofacial Pain (OFP) affects 15% of the general population. OFP conditions can be myofascial, also known as temporomandibular disorders (TMDs) or neuropathic. The underlying pathophysiology in several chronic OFP conditions, is unknown.

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Can systemic antibiotics reduce the need for surgical intervention in treating peri-implantitis?

Evid Based Dent

December 2024

MClinDent Prosthodontics Specialty Trainee, Eastman Dental Institute, London, United Kingdom.

Article Synopsis
  • A study was done to see if using antibiotics (amoxicillin and metronidazole) along with treatment helps people with a gum disease called peri-implantitis avoid surgery.
  • Out of 57 patients, 45 were observed, with some getting the treatment with antibiotics and others without.
  • In the end, over half of the patients didn't need surgery, but the results weren't super different between those who got antibiotics and those who didn't.
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Article Synopsis
  • The study aimed to evaluate hearing outcomes at 24 months for infants with mild congenital cytomegalovirus (cCMV) infection, comparing those who received antiviral treatment to those who did not.
  • Utilizing data from the European Registry of Children with cCMV, researchers included infants diagnosed with cCMV early in life, who had normal physical exams and mild imaging findings.
  • Results showed that 34.7% of the 196 participants received antiviral treatment, but there was no significant difference in hearing loss prevalence between treated (4.6%) and untreated groups (6.3%) after two years.
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Article Synopsis
  • The study explored the use of the HOLOBalance platform, which employs augmented reality holograms for providing multisensory physiotherapy to older adults at risk of falls.
  • A pilot randomised controlled trial showed that the platform was safe, feasible, and well-accepted, with 69% of participants recommending it.
  • Participants demonstrated significant improvements in functional gait and balance (measured through FGA and Mini BESTest), outperforming the traditional OTAGO programme.
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Evaluation of Post-Operative Pain and Healing in Single-Visit versus Multiple-Visit Root Canal Therapy.

J Pharm Bioallied Sci

July 2024

Graduate Medical Education (GME) Residency Program, Eastman Institute for Oral Health, University of Rochester, Rochester, NY, United States.

Background: " (RCT)" is a common endodontic procedure targeted at preserving teeth compromised by pulp infection. The debate over the optimal number of visits for RCT remains inconclusive, with single- and multiple-visit approaches both being advocated.

Methods: A prospective research was conducted on 100 subjects undergoing RCT at a tertiary care center.

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Assessment of Factors Affecting the Success of Endodontic Retreatment Procedures.

J Pharm Bioallied Sci

July 2024

BDS MPH, Graduate Medical Education (GME) Residency Program, Eastman Institute for Oral Health, University of Rochester, New York, USA.

Background: Endodontic retreatment is crucial for preserving dental health but is influenced by various factors.

Objective: This research aimed to assess factors affecting the success of endodontic retreatment procedures.

Methods: A retrospective analysis was conducted on 250 cases of endodontic retreatment.

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Evaluating the Efficacy of Adjuvant Radiotherapy in the Management of Advanced Oral Cancer Cases.

J Pharm Bioallied Sci

July 2024

Department of Oral and Maxillofacial Surgery, Meenakshi Medical College and Research Institute, Meenakshi Academy of Higher Education and Research, Enathur, Tamil Nadu, India.

Background: Because of its high rates of morbidity and death, especially in its late stages, oral cancer poses a serious threat to world health. Even with improvements in surgical and chemotherapeutic techniques, advanced oral cancer is still difficult to treat and frequently has unfavorable results.

Methods: Information on demographics, tumor features, treatment options, and results were gathered from medical records.

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A qualitative study of preoperative anxiety in orthognathic patients: The patient perspective.

Am J Orthod Dentofacial Orthop

January 2025

Department of Orthodontics, UCL Eastman Dental Institute, London, United Kingdom; Royal National ENT and Eastman Dental Hospitals, UCLH NHS Foundation Trust, London, United Kingdom.

Introduction: Increased preoperative anxiety may have an adverse impact on the patient experience. This qualitative study therefore aimed to explore those factors affecting anxiety in the approach to orthognathic surgery.

Methods: A total of 28 orthognathic patients who had completed their presurgical orthodontic treatment and were within 8 weeks before their surgery underwent one-to-one in-depth interviews.

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Ex Ovo Chorioallantoic Membrane Assay as a Model of Bone Formation by Biomaterials.

ACS Macro Lett

October 2024

Regenerative Biomaterials Research Group, The RAFT Institute and The Griffin Institute, Northwick Park and Saint Mark's Hospitals, Harrow HA1 3UJ, United Kingdom.

Article Synopsis
  • - Biomaterials, essential for bone tissue engineering, require careful selection and assessment for effective clinical use, as existing models often face challenges like high costs and ethical concerns.
  • - Researchers proposed using the chick embryo chorioallantoic membrane as a model to test initial bone formation with scaffolds, specifically a fibrin-alginate-calcium phosphate (FACaP) material.
  • - Initial results showed early signs of bone formation and blood vessel infiltration in the scaffolds, making FACaP a promising biomaterial for applications where heavy load-bearing isn't necessary.
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Purpose: Upper airway (UA) surgery is commonly employed in the treatment of patients with obstructive sleep apnea (OSA). The intricate pathophysiology of OSA, variability in sites and patterns of UA collapse, and the interaction between anatomical and non-anatomical factors in individual patients may contribute to possible surgical failures. This clinical consensus statement aims to identify areas of agreement among a development group comprising international experts in OSA surgery, regarding the appropriate definition, predictive factors in patients, and management of surgical failure in OSA treatment.

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