Pica practices, anemia, and oral health outcomes: a systemic review.

Objectives: Pica is a non-nutritive eating behavior. The potential impact of pica on oral health and the association between pica and anemia are understudied. We examined the current evidence on the relationship between pica practices, anemia, and oral health outcomes.

Association between adult-onset hearing loss and dementia biomarkers: A systematic review.

Background And Objective: People with adult-onset hearing loss (AoHL) are at increased dementia risk. In this study, we explore potential aetiological mechanisms by synthesising the evidence on the association between AoHL and neuropathological, cerebrospinal fluid (CSF), blood and imaging biomarkers of dementia.

Methods: We systematically searched electronic databases from inception to 30 April 2024 for cross-sectional and longitudinal studies, including quantitative data on the association between AoHL and dementia biomarkers.

The translational potential of inflammation-induced skin blister human models in exploring the pathogenesis of periodontitis and its systemic health implications.

Periodontitis is a highly prevalent chronic disease. Despite decades of extensive research on the topic, a complete understanding of its immunopathogenesis, especially when linked to other inflammatory comorbidities, is lacking. human and animal experiments have shown the host inflammatory response's crucial role in both the disease's onset and its systemic implications.

Psychosocial determinants of oral health outcomes in young children.

Objective: To examine the social determinants of early childhood caries (ECC), one of the greatest public health risks affecting children, and examine alternative pathways of influence.

Methods: A physically healthy, socio-demographically high-risk sample of initially caries-free children, aged 1-4 years, was prospectively studied for 2 years. At 6-month intervals, assessments were made of caries presence from a standard dental exam; oral microbiology was assayed from saliva samples; oral hygiene behaviors and psychological and psychosocial risk exposure were derived from interviews and questionnaires.

Remote appointments in Orthodontics and Oral and Maxillofacial Surgery: Part 1 service evaluation.

Objective: To assess the type, number and outcome of remote appointments in Orthodontics and Oral and Maxillofacial Surgery (OMFS) in one acute hospital trust and to establish whether remote appointments carried out during the Covid-19 pandemic were successful in saving a face-to-face appointment.

Design: Service evaluation.

Setting: Orthodontic and OMFS departments at Buckinghamshire Healthcare NHS Trust.

Remote appointments in orthodontics and oral and maxillofacial surgery: Part 2 clinician perceptions.

Objectives: To assess clinician perceptions of and satisfaction with remote appointments in orthodontics and oral and maxillofacial surgery (OMFS).

Design: Cross-sectional questionnaire-based study.

Setting: Orthodontic and OMFS departments in six acute NHS hospital Trusts in the UK.

Non-healing extraction socket: a diagnostic challenge for general dental practitioners.

Introduction In the UK, more than 18 million extractions are performed annually. Healing after extraction is often uneventful, but there are rare cases where weeks or months pass and an extraction socket does not heal.Aim The aim of this study is to provide a review of cases in which a non-healing extraction socket is attributed to a serious systemic disease or malignancy, or an adverse consequence of systemic therapy.

Efficacy of cold and cryo-preserved nerve allografts with low-dose FK506 for motor nerve regeneration: a preclinical study.

Background: Despite their ability to regenerate as well as autografts, the use of nerve allografts is limited by the need for immunosuppression and the risk of disease transmission. Further, decellularized allografts lacking Schwann cells limit axonal regeneration in long nerve defects. This study evaluated sciatic nerve regeneration in rats implanted with cold- or cryopreserved allografts, and examined the effects of FK506, an immunosuppressant that targets calcineurin function, on motor recovery.

Dental implant site preparation with conventional rotary drill or piezosurgery: five-year after placement results from a within person randomised controlled trial.

Purpose: To evaluate whether there are clinical benefits by preparing dental implant sites using piezosurgery instead of conventional rotary drills in healed bone crests and if initial crestal soft tissue thickness could have an impact on marginal bone loss.

Methods: Twenty-five partially edentulous patients requiring two single implants in molar/premolar areas had each site randomly allocated to either piezosurgery or to conventional rotary drill preparation according to a split-mouth design. Definitive screw-retained metal-ceramic crowns were delivered after 6 months.

The Efficacy of Multiwavelength Red and Near-Infrared Transdermal Photobiomodulation Light Therapy in Enhancing Female Fertility Outcomes and Improving Reproductive Health: A Prospective Case Series with 9-Month Follow-Up.

: Female infertility due to unexpected causes exhibits a great challenge for both clinicians and women who are trying to conceive. The present clinical case series study aimed to evaluate the efficacy of multiple wavelengths of red and near-infrared (NIR) laser photobiomodulation (PBM) for increasing the potential of fertility in women and improving reproductive health in unexplained infertility issues. The objectives were to assess the following: (1) any adverse effects; (2) the possibility of producing an effective PBM protocol; (3) and healthy live birth.

Influence of Soft and Stiff Matrices on Cytotoxicity in Gingival Fibroblasts: Implications for Soft Tissue Biocompatibility.

The biocompatibility of dental materials is critical for ensuring safety in clinical applications. However, standard in vitro cytotoxicity assays often rely on stiff tissue culture plastic (TCP), which does not accurately replicate the biomechanical properties of soft oral tissues. In this study, we compared human gingival fibroblasts (HGFs) cultured on soft, gel-based substrates mimicking gingival tissue stiffness (0.

Auditory processing deficits in subacute stroke.

Background: Stroke is the second leading cause of disability worldwide. Stroke results in focal neurological deficit and often leads to auditory problems due to its impact on the auditory pathway. Altered connections in the auditory pathway, caused by stroke, can result in hearing difficulties ranging from impaired sound detection to altered auditory perception.

Orthodontic Trainees' Perceptions of Effective Feedback in the United Kingdom.

Introduction: Feedback is an invaluable educational tool and is now widely used in education, despite some of the challenges and barriers to its implementation. Effective feedback in medical and dental education is a driver for improvement, by recognising good performance and identifying areas where improvement is required. This, in turn, can translate into better patient care, as feedback can positively impact on clinical performance.

Oral health care pathways for patients with epidermolysis bullosa: A position statement from the European reference network for rare skin diseases.

Background: Inherited epidermolysis bullosa (EB) comprises a group of genetic disorders characterized by skin fragility and unique oral features. It requires interdisciplinary care from several health professionals, including oral health teams. Modern dentistry encompasses a wide range of therapeutic options performed by specialists from different fields.

Can fluoxetine influence orthodontic tooth movement? A systematic review and meta-analysis of studies on animal models.

Introduction: Selective serotonin reuptake inhibitors (SSRIs) such as fluoxetine adversely affect bone mineral density (BMD) and turnover, thereby increasing the risk of fractures. The objective of the present systematic review and meta-analysis was to evaluate studies on animal models that assessed whether fluoxetine can influence orthodontic tooth movement (OTM).

Material And Methods: Indexed databases (PubMed/Medline, EMBASE, Cochrane Library, Scopus and ISI Web of Knowledge) and Google Scholar were searched without time and language barriers up to and including June 2024.

Accuracy of Intraoral Scanner Systems for Fabricating Inlay, Onlay, and Veneer Restorations: A Systematic Review and Meta-Analysis.

Purpose: To evaluate the accuracy of intraoral scanners (IOSs) for fabricating inlay, onlay, and veneer restorations.

Materials And Methods: A literature search was completed in five databases: PubMed/Medline, Scopus, Embase, Web of Science, and Cochrane. A manual search was also conducted.

The effectiveness of fractal analysis in diagnosing temporomandibular joint disorders: a systematic review of clinical studies.

Objective: This study aims to evaluate the application and effectiveness of fractal analysis (FA) in assessing temporomandibular joint disorders (TMDs) with dental imaging.

Methods: This systematic review, conducted in adherence to PRISMA-P and Cochrane Handbook guidelines, involved a comprehensive search of five electronic indexed databases up to September 15, 2024. The thorough search aimed to ensure the inclusion of all relevant studies on dental imaging with fractal dimension (FD) analysis for TMDs.

Endotyping in Chronic Rhinosinusitis-An EAACI Task Force Report.

Chronic rhinosinusitis (CRS) is a clinical syndrome defined by typical sinonasal symptoms persisting for at least 12 weeks. CRS is divided into two distinct phenotypes, CRS with nasal polyps (CRSwNP) and without (CRSsNP). The aim of the review is to provide an update on the current knowledge in CRS endotypes.

The Effect of Carbodiimide Crosslinkers on Gelatin Hydrogel as a Potential Biomaterial for Gingival Tissue Regeneration.

Connective tissue grafts for gingival recession treatment present significant challenges as they require an additional surgical site, leading to increased morbidity, extended operative times, and a more painful postoperative recovery for patients. Gelatin contains the arginine-glycine-aspartic acid (RGD) sequence, which supports cell adhesion and interactions. The development of gelatin hydrogels holds significant promise due to their biocompatibility, ease of customization, and structural resemblance to the extracellular matrix, making them a potential candidate for gingival regeneration.

Effect of Zinc on improving silver diamine fluoride-derived tooth discoloration in vitro.

Background: Silver Diamine Fluoride (SDF) is effective for arresting dental caries, presenting a valuable non-invasive treatment option in dentistry. Despite its therapeutic advantages, a significant drawback is the tooth discoloration that follows its application, which can affect patient acceptance. Addressing this aesthetic concern without diminishing the treatment's efficacy remains challenging in dental practice.

Digital Workflow for a Definitive Implant-Supported Hybrid Prosthesis.

Implant-supported hybrid prostheses have become popular solutions when treating patients with terminal dentitions or who are completely edentulous. Since the implementation of osseointegrated dental implants to treat edentulism, multiple prosthetic designs and materials have been used for full-arch fixed hybrid prostheses. While these restorations can be highly successful, the most common restorative failures are attributed to lack of prosthetic space or a framework without passive fit, consequently leading to possible chippings, delamination, and/or fractures.

In Vitro Osteo-Immunological Responses of Bioactive Calcium Phosphate-Containing Urethane Dimethacrylate-Based Composites: A Potential Alternative to Poly(methyl methacrylate) Bone Cement.

This investigation developed new composite bone cements using urethane dimethacrylate (UDMA), poly(propylene glycol) dimethacrylate (PPGDMA), and hydroxyethyl methacrylate (HEMA), with micrometer-sized aluminosilicate glass filler. Monocalcium phosphate monohydrate (MCPM) and hydroxyapatite (HA) particles were added to enhance biological performance, particularly osteo-immunomodulation. Free radical polymerization was triggered by mixing two pastes containing either benzoyl peroxide (BPO, an initiator) or N-tolyglycine glycidyl methacrylate (NTGGMA, an activator).

Nanotechnology in healthcare, and its safety and environmental risks.

Nanotechnology holds immense promise in revolutionising healthcare, offering unprecedented opportunities in diagnostics, drug delivery, cancer therapy, and combating infectious diseases. This review explores the multifaceted landscape of nanotechnology in healthcare while addressing the critical aspects of safety and environmental risks associated with its widespread application. Beginning with an introduction to the integration of nanotechnology in healthcare, we first delved into its categorisation and various materials employed, setting the stage for a comprehensive understanding of its potential.

A novel 'stop-hole' strategy to extend the fatigue life of orthodontic thermoformed retainers: an in vitro study.

Objectives: This study aimed to investigate the potential to limit crack propagation in thermoformed retainers (TRs) and extend their fatigue life by placing a 'stop-hole'.

Methods: Thirty-two TRs, fabricated from 1 mm thick, round polyethylene terephthalate glycol (PETG) blanks of ICONIC®, underwent testing within a custom-built fatigue tester. After initial crack growth of 3 mm, the TRs were divided into three groups: a control group (C) and two experimental groups based on the stop-hole placement method.