Straightforward synthesis of quinazolin-4(3)-ones visible light-induced condensation cyclization.

A green, simple and efficient method is developed for the synthesis of quinazolin-4(3)-ones visible light-induced condensation cyclization of 2-aminobenzamides and aldehydes under visible light irradiation. The reaction proceeds using fluorescein as a photocatalyst in the presence of TBHP without the need for a metal catalyst. In addition, this reaction tolerates a broad scope of substrates and could afford a variety of desirable products in good to excellent yields.