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Recent advances and perspectives in synthetic applications of silylboronates as silyl radical precursors.

Chem Sci

December 2024

State Key Laboratory of Petroleum Molecular & Process Engineering, Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University Shanghai 200062 P. R. China

Silylboronates, as powerful and versatile reagents, have been widely used in synthetic chemistry over the past few decades, due to their ability to incorporate silicon and boron atoms into organic molecules. With the rapid development of radical chemistry, the use of silylboronates as silyl radical precursors has recently become a research focus in organic synthesis. Significant achievements have been made in the synthetic applications of silylboronates as silyl radical sources for various C-Si and C-X bond forming transformations.

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