21 results match your criteria: "East Center of Burns Treatment and Reconstructive Surgery[Affiliation]"
: Children make up a large percentage of those affected by burns worldwide, with most of them suffering from severe injuries that necessitate skilled medical attention. Despite medical progress, there is still no ideal dressing for the treatment of burn wounds in children. The aim of the study was to assess the impact of epidermal substitutes in the treatment of burn wounds in children.
View Article and Find Full Text PDFPol Przegl Chir
July 2024
East Center of Burns Treatment and Reconstructive Surgery, Medical University of Lublin, Leczna, Poland, Department of Plastic Surgery, Reconstructive Surgery and Burn Treatment, Medical University of Lublin, Polish Students' Scientific Association of Medical Simulation, Poland.
Ann Transplant
November 2024
East Center of Burns Treatment and Reconstructive Surgery, District Hospital, Łęczna, Poland.
BACKGROUND Acute kidney injury (AKI) is a common issue in intensive care units and is a potentially lethal consequence of severe burns. In severely burned patients with non-renal indications, renal replacement treatment is frequently used. This study's aim was to compile a 10-year summary of continuous renal replacement therapy (CRRT) experience at a single burn center, including patient outcomes, effectiveness, and potential complications in the context of severe burns.
View Article and Find Full Text PDFLife (Basel)
December 2023
East Center of Burns Treatment and Reconstructive Surgery, 21-010 Lęczna, Poland.
The goal of burn wound treatment is to ensure rapid epithelialization in superficial burns and the process of rebuilding the lost skin in deep burns. Topical treatment plays an important role. One of the innovations in the field of synthetic materials dedicated to the treatment of burns is epidermal skin substitutes.
View Article and Find Full Text PDFInt J Mol Sci
August 2023
Department of Plastic and Reconstructive Surgery and Microsurgery, Medical University of Lublin, 20-059 Lublin, Poland.
The coagulation and immune systems, two vital systems in the human body, share intimate connections that fundamentally determine patient health. These systems work together through several common regulatory pathways, including the Tissue Factor (TF) Pathway. Immune cells expressing TF and producing pro-inflammatory cytokines can influence coagulation, while coagulation factors and processes reciprocally impact immune responses by activating immune cells and controlling their functions.
View Article and Find Full Text PDFInt J Environ Res Public Health
January 2023
East Center of Burns Treatment and Reconstructive Surgery, Medical University of Lublin, 20-059 Lublin, Poland.
Toxic epidermal necrolysis, Leyll's syndrome (TEN), is a rare mucocutaneous blistering disease burdened with high mortality rates. The diagnosis of TEN is based on clinical symptoms and histopathological findings. In approximately 90% of cases, it is a severe adverse reaction to drugs.
View Article and Find Full Text PDFIn the original publication, there was a mistake in Table 2 as published [...
View Article and Find Full Text PDFInt J Mol Sci
December 2022
East Center of Burns Treatment and Reconstructive Surgery, Medical University of Lublin, 21-010 Leczna, Poland.
Mesenchymal stem cells have a known regenerative potential and are used in many indications. They secrete many growth factors, including for fibroblasts (FGF), endothelium (VEGF), as well as 14 anti-inflammatory cytokines, and they stimulate tissue regeneration, promoting the secretion of proteins and glycosaminoglycans of extracellular matrices, such as collagen I, II, III, and V, elastin, and also metalloproteinases. They secrete exosomes that contain proteins, nucleic acids, lipids, and enzymes.
View Article and Find Full Text PDFBMC Med Inform Decis Mak
October 2022
East Center of Burns Treatment and Reconstructive Surgery, Medical University of Lublin, Łęczna, Poland.
Background: Toxic epidermal necrolysis (TEN) patients require multi-directional and multi-disciplinary treatment. In most cases, they are hospitalised at intensive care units and require multi-directional, burn-complication preventive care. Choosing the most appropriate treatment option might be troublesome even when predicting scores are used.
View Article and Find Full Text PDFInt J Mol Sci
September 2022
Department of Dermatology, Venereology and Allergology, Faculty of Medicine, Medical University of Gdansk, Smoluchowskiego 17, 80-214 Gdansk, Poland.
Recently, interest in the microbiome of cutaneous diseases has increased tremendously. Of particular interest is the gut-brain-skin axis proposed by Stokes and Pillsbury in 1930. The microbiome has been suggested in the pathogenesis of hidradenitis suppurativa, however the link between the commensals and the host is yet to be established.
View Article and Find Full Text PDFDermatol Ther
November 2022
East Center of Burns Treatment and Reconstructive Surgery, Medical University of Lublin, Łęczna, Poland.
Comprehensive scar treatment usually requires a combination of several methods. The selection of methods should depend on the appearance and biology of the scar. The aim of this study was to determine the safety and efficiency of combined methods with the use of autologous derived agents in the treatment of scars, based on the available literature and own experience.
View Article and Find Full Text PDFInt J Mol Sci
August 2022
Department of Dermatology, Venereology and Allergology, Faculty of Medicine, Medical University of Gdansk, Smoluchowskiego 17, 80-214 Gdansk, Poland.
J Clin Med
August 2022
Chair and Department of Didactics and Medical Simulation, Medical University of Lublin, 20-093 Lublin, Poland.
Introduction: Early eschar removal is the standard management of burns. The goal is to remove all of the necrotic tissue and render the wound suitable for healing or skin grafting. The enzymatic debridement of burn wounds allows for minimally invasive removal of burn eschar.
View Article and Find Full Text PDFMil Med Res
August 2022
East Center of Burns Treatment and Reconstructive Surgery, 21-010, Łęczna, Poland.
J Clin Med
April 2022
Chair and Department of Didactics and Medical Simulation, Medical University of Lublin, 20-093 Lublin, Poland.
Burns are one of the most common causes of home injuries, characterized by serious damage to the skin and causing the death of affected tissues. In this review, we intended to collect information on the pathophysiological effects of burns in pediatric patients, with particular emphasis on local and systemic responses. A total of 92 articles were included in the review, and the time range of the searched articles was from 2000 to 2021.
View Article and Find Full Text PDFJ Burn Care Res
November 2022
East Center of Burns Treatment and Reconstructive Surgery, Medical University of Lublin, Łęczna, Poland.
Lyell's syndrome, or toxic epidermal necrolysis (TEN) is a rare but life-threatening condition. It manifests with blistering of skin and mucous due to subepidermal bullae and keratinocyte necrosis. In most cases, it is an immune response to drugs or their metabolites.
View Article and Find Full Text PDFGels
February 2022
East Center of Burns Treatment and Reconstructive Surgery, 21-010 Leczna, Poland.
Inert hydrogels are of a great importance in burn first aid. Hydrogel dressings may be an alternative to cooling burn wounds with streaming water, especially in cases of mass casualty events, lack of clean water, hypothermia, or large extent of burns. Hydrogels that contain mostly water evacuate the heat cumulating in the skin by evaporation.
View Article and Find Full Text PDFMed Sci Monit
January 2022
The East Center of Burns Treatment and Reconstructive Surgery, District Hospital, Łęczna, Poland.
BACKGROUND The supplementary treatment of burns with enzymatic debridement with Nexobrid® was approved in Europe in 2013. The 2017 European consensus guidelines on the removal of eschar in burns by bromelain-based enzymatic debridement were updated in 2020. This questionnaire-based study aimed to obtain a consensus from 5 Polish burns centers on eschar removal by Nexobrid® in burns following the 2020 updated European consensus guidelines.
View Article and Find Full Text PDFJ Pers Med
January 2022
East Center of Burns Treatment and Reconstructive Surgery, 77-069 Łęczna, Poland.
The interest in regenerative medicine is increasing, and it is a dynamically developing branch of aesthetic surgery. Biocompatible and autologous-derived products such as platelet-rich plasma or adult mesenchymal stem cells are often used for aesthetic purposes. Their application originates from wound healing and orthopaedics.
View Article and Find Full Text PDFInt J Mol Sci
January 2022
East Center of Burns Treatment and Reconstructive Surgery, ul. Krasnystawska 52, 21-010 Łęczna, Poland.
In the literature, burns are understood as traumatic events accompanied by increased morbidity and mortality among affected patients. Their characteristic feature is the formation of swelling and redness at the site of the burn, which indicates the development of inflammation. This reaction is not only important in the healing process of wounds but is also responsible for stimulating the patient's innate immune system.
View Article and Find Full Text PDFBurns
December 2021
East Center of Burns Treatment and Reconstructive Surgery, Medical University of Lublin, Łęczna, Poland; Chair and Department of Didactics and Medical Simulation, Medical University of Lublin, Poland.