557 results match your criteria: "Ear and Throat Hospital[Affiliation]"

Utilization of hyperbaric oxygen therapy in oculoplastic surgery: A case series.

J Fr Ophtalmol

December 2024

Edward Harkness Eye Institute, Department of Ophthalmology, Columbia University Irving Medical Center, New York, NY, United States. Electronic address:

Objective: Hyperbaric oxygen therapy (HBOT) has emerged as a versatile tool in the management of an array of medical conditions, including tissue ischemia and delayed wound healing. Despite the incorporation of HBOT in other medical fields, HBOT is not routinely utilized in the field of ophthalmic plastic and reconstructive periorbital surgery.

Design: Case series.

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Abdominoplasty continues to be a frequently performed plastic surgery procedure. Futhermore, an increase in both surgical and medical weight loss is contributing to the procedure's increasing popularity. Technical refinements have improved surgical outcomes and safety.

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BACKGROUND Trastuzumab (Herceptin) is a recombinant DNA-derived humanized monoclonal antibody that the US Food and Drug Administration (FDA) approved in 1998 for metastatic human epidermal growth factor receptor 2 (HER2)-positive breast cancer therapy. It selectively binds to the extracellular domain of HER2 and mediates an antibody-dependent cellular toxicity in various tissues. Trastuzumab use alone does not typically cause aggressive ocular complications.

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Article Synopsis
  • The study analyzes the FDA's MAUDE database to identify and characterize adverse events linked to femtosecond (FS) laser-assisted LASIK surgeries from January 2012 to April 2022.
  • A total of 1,136 relevant adverse events were identified from 3,491 reports, with common intraoperative complications being incomplete cuts and difficulties with the flap, while diffuse lamellar keratitis (DLK) was the most frequent postoperative issue.
  • This research highlights the prevalence of specific complications during and after FS-assisted LASIK and aims to improve awareness and patient counseling for ophthalmologists.
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Nasal Tip Deprojection in Rhinoplasty.

Plast Reconstr Surg

August 2024

Department of Plastic Surgery, Manhattan Eye, Ear and Throat Hospital, New York, NY, USA.

Background: Rhinoplasty is one of the most commonly performed facial surgeries in the USA. There exist many major and minor nasal tip support structures that impact tip projection. Overprojection may result from anatomic factors or may occur iatrogenically during primary rhinoplasty.

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Background: Fresh frozen costal cartilage (FFCC), from the Musculoskeletal Transplant Foundation (MTF), has recently gained popularity for use in revision rhinoplasty or primary rhinoplasty when there is a paucity of autologous cartilage. However, there are currently no guidelines related to the use of intraoperative antibiotic soaking to reduce postoperative infection rates when using MTF FFCC. This study aimed to evaluate the efficacy of intraoperative antibiotic soaks in reducing surgical site infection rate when using MTF FFCC grafts in rhinoplasty.

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Background: Traditional rhinoplasty tip grafts often lead to visibility issues, prompting patients to seek revision surgery. The mastoid fascia tissue graft (MFTG) provides a natural-looking alternative with an acceptable risk of complication. MFTG remains less visible through the skin and helps camouflage and conceal tip irregularities.

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Early evaluation and treatment of periorbital infantile hemangiomas (POIH) were associated with lower rates of ophthalmological complications. To evaluate age and characteristics associated with improved anisometropic astigmatism (anisoastigmatism) and eye symmetry measured by diopters and a 5-point scale, respectively, in patients with POIH treated with surgical excision. A retrospective study was performed on patients with POIH.

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Corneal Complications Related to Dupilumab Use.

Eye Contact Lens

June 2024

Manhattan Eye, Ear and Throat Hospital/ Northwell Eye Institute (J.T., D.C.R.), New York, NY; and Department of Ophthalmology (J.T., J.J.K.), Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY.

Objectives: The aim of this report is to describe atypical corneal complications associated with dupilumab use.

Methods: This is a series of four cases of adult patients with infiltrative or ulcerative keratitis secondary to dupilumab use.

Results: All four patients in this series were prescribed dupilumab for the treatment of atopic dermatitis and developed infiltrative or ulcerative corneal lesions.

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Purpose: The purpose of this study was to investigate the utility of steady state pattern electroretinogram (ss-PERG) in detecting retinal ganglion cell (RGC) dysfunction in glaucoma suspects (GS) who had normal 24-2 Humphrey Visual Fields (HFA).

Materials And Methods: This was a prospective cohort study of GS patients who were identified based on optic disc appearance with normal HFAs. Patients received a complete eye examination, standard automated perimetry (SAP), optical coherence tomography (OCT), and ss-PERG measurements.

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Central serous chorioretinopathy: An evidence-based treatment guideline.

Prog Retin Eye Res

July 2024

Department of Ophthalmology, Leiden University Medical Center, Leiden, the Netherlands; Department of Ophthalmology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands. Electronic address:

Central serous chorioretinopathy (CSC) is a relatively common disease that causes vision loss due to macular subretinal fluid leakage and it is often associated with reduced vision-related quality of life. In CSC, the leakage of subretinal fluid through defects in the retinal pigment epithelial layer's outer blood-retina barrier appears to occur secondary to choroidal abnormalities and dysfunction. The treatment of CSC is currently the subject of controversy, although recent data obtained from several large randomized controlled trials provide a wealth of new information that can be used to establish a treatment algorithm.

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Optic Disc Edema Is an Under-Recognized Feature of Birdshot Chorioretinitis.

J Neuroophthalmol

January 2024

Washington University in St. Louis School of Medicine (SS, GVS, LMH), St. Louis, Missouri; Indiana University School of Medicine (VJM, RSM), Indianapolis, Indiana; John A. Moran Eye Center (A. Shakoor, AV), University of Utah, Salt Lake City, Utah; Sue Anschutz-Rogers Eye Center (AGP), University of Colorado School of Medicine, Denver, Colorado; Wilmer Eye Institute (JET), Johns Hopkins University School of Medicine, Baltimore, Maryland; Northwestern University Feinberg School of Medicine (DAG), Chicago, Illinois; CT Uveitis Foundation (PAG), West Hartford, ConnecticutManhattan Eye, Ear and Throat Hospital (NG), New York, New York; Hospital Universario Austral (A. Schlaen), Austral University, Buenos Aires, Argentina; Tennessee Retina (AT), Nashville, Tennessee; Rush University/Illinois Retina Associates (PTM, VR), Chicago, Illinois; Cole Eye Institute (PL), Cleveland Clinic, Cleveland, Ohio; University of Puerto Rico (ALO), San Juan, Puerto Rico; Associated Vitreoretinal and Uveitis Consultants (RSM), Carmel, Indiana; SightMD (GC), Yonkers, New York; Fundacion Jimenez Diaz University Hospital (EC), Madrid, Spain; and Mayo Clinic (WMS), Rochester, Minnesota.

Background: Optic disc edema is a feature of many ophthalmic and neurologic conditions. It remains an underappreciated feature of birdshot chorioretinitis (BSCR), leading to delay in diagnosis and treatment. The purpose of our study was to identify clinical features that are concomitant with optic disc edema and suggest a diagnosis of BSCR.

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Aim And Background: To evaluate the ability of pattern electroretinogram (PERG) to detect improvement of retinal ganglion cell (RGC) function in glaucoma suspects (GS) after medically reducing intraocular pressure (IOP) using prostaglandin analog drops.

Materials And Methods: Six subjects (eight eyes) received topical IOP lowering treatment based on their clinical examination and were observed at Manhattan Eye, Ear & Throat Hospital over an average of 3.1 ± 2.

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Limited Incision Rhinoplasty: An Approach for All Primary and Revision Cases.

Aesthetic Plast Surg

February 2024

Department of Plastic Surgery, Manhattan Eye, Ear and Throat Hospital, 210 E. 64th Street, 950 Park Ave, New York, NY, 10065, USA.

Introduction: Rhinoplasty was one of the most frequently performed aesthetic surgeries in the USA in 2022. Traditionally, the open approach has been preferred by the majority of surgeons often due to familiarity and ease of visualization. However, patient interest in closed and preservation rhinoplasty is driving a resurgence in the popularity of endonasal techniques.

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The purpose of this study was to determine which biomechanical variables measured during the baseball swing are associated with linear bat speed at ball contact (bat speed). Twenty collegiate baseball players hit a baseball from a tee into a net. Kinematics were recorded with a motion capture system sampling at 500 Hz and kinetics were measured by force plates under each foot sampling at 1000 Hz.

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Background: Rhinoplasty is made more challenging when there is insufficient septal cartilage for use as graft material. Several autologous and homologous graft options have been used in the past, although each comes with its own set of challenges. Fresh-frozen costal cartilage (FFCC) is an increasingly popular alternative that yields the benefits of homologous tissue while having a lower theoretical risk profile.

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Article Synopsis
  • Open imaging fluorescence devices using indocyanine green (ICG) have been tested in surgical procedures related to the periorbital area to visualize blood flow and lymphatic drainage.
  • A prospective study conducted from 2021 to 2022 involved 22 patients for ICG angiography and 10 for ICG lymphangiography, successfully showing the vascular supply and lymphatic systems in various surgical contexts.
  • The findings demonstrated that ICG is effective in assessing blood circulation in ocular surgeries and understanding lymphatic pathways, improving surgical outcomes and patient care.
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Introduction: ChatGPT represents a potential resource for patient guidance and education, with the possibility for quality improvement in healthcare delivery. The present study evaluates the role of ChatGPT as an interactive patient resource, and assesses its performance in identifying, triaging, and guiding patients with concerns of postoperative complications following facelift and neck lift surgery.

Methods: Sixteen patient profiles were generated to simulate postoperative patient presentations, with complications of varying acuity and severity.

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Introduction: Hyalocytes have been recognized as resident tissue macrophages of the vitreous body since the mid-19 century. Despite this, knowledge about their origin, turnover, and dynamics is limited.

Areas Covered: Historically, initial studies on the origin of hyalocytes used light and electron microscopy.

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Ten-Year Outcomes of LASIK for Pediatric Myopic Anisometropia.

Clin Ophthalmol

December 2022

Department of Ophthalmology, Florida International University, Herbert Wertheim College of Medicine & Glaucoma Research Organization, Miami, FL, USA.

Purpose: To evaluate long-term safety, effectiveness, and stability of unilateral LASIK in pediatric myopic anisometropic amblyopia.

Methods: This retrospective study included children who received unilateral LASIK for myopic anisometropia of >6 D, after mandatory 6-month occlusion/penalization therapy. They were evaluated at 6 months, 1 year, 2 years and biannually until 10 years.

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Due to the clinically established safety and efficacy profile of recombinant adeno-associated viral (rAAV) vectors, they are considered the "go to" vector for retinal gene therapy. Design of a rAAV-mediated gene therapy focuses on cell tropism, high transduction efficiency, and high transgene expression levels to achieve the lowest therapeutic treatment dosage and avoid toxicity. Human retinal explants are a clinically relevant model system for exploring these aspects of rAAV-mediated gene delivery.

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