39 results match your criteria: "EPFL - Swiss Federal Institute of Technology[Affiliation]"

Science and technology: a framework for peace.

Commun Eng

November 2024

EPFL - Swiss Federal Institute of Technology in Lausanne, EssentialTech Centre, Lausanne, Switzerland.

With global conflicts on the rise, it is crucial for transdisciplinary researchers to become more actively involved in leveraging technology to promote peace. After years of experience and discussions with multiple stakeholders, we have identified specific aspects that require greater attention from science, technology, engineering and mathematics scientists. To address these, we propose a practical framework designed to better integrate professionals from technical disciplines into the field of PeaceTech.

View Article and Find Full Text PDF

In the wealthy and orderly city of Geneva, Switzerland, accommodation centres built in haste between the 1950s and the 1980s to house seasonal guestworkers from southern Europe are still standing and still inhabited. Today's residents are precarious workers, undocumented or with temporary permits as well as asylum seekers. While the seasonal status disappeared in the early 2000s, the demand for low-skilled, flexible labour did not.

View Article and Find Full Text PDF

The decline of motor ability is a hallmark feature of aging and is accompanied by degeneration of motor synaptic terminals. Consistent with this, Drosophila motor synapses undergo characteristic age-dependent structural fragmentation co-incident with diminishing motor ability. Here, we show that motor synapse levels of Trio, an evolutionarily conserved guanine nucleotide exchange factor (GEF), decline with age.

View Article and Find Full Text PDF

Puckered and JNK signaling in pioneer neurons coordinates the motor activity of the Drosophila embryo.

Nat Commun

December 2023

Instituto de Biología Molecular de Barcelona (CSIC), Parc Cientific de Barcelona, Baldiri Reixac 10-12, 08028, Barcelona, Spain.

Central nervous system organogenesis is a complex process that obeys precise architectural rules. The impact that nervous system architecture may have on its functionality remains, however, relatively unexplored. To clarify this problem, we analyze the development of the Drosophila embryonic Ventral Nerve Cord (VNC).

View Article and Find Full Text PDF

Alteration of the levels, localization or post-translational processing of the microtubule associated protein Tau is associated with many neurodegenerative disorders. Here we develop adult-onset models for human Tau (hTau) toxicity in Drosophila that enable age-dependent quantitative measurement of central nervous system synapse loss and axonal degeneration, in addition to effects upon lifespan, to facilitate evaluation of factors that may contribute to Tau-dependent neurodegeneration. Using these models, we interrogate the interaction of hTau with the retromer complex, an evolutionarily conserved cargo-sorting protein assembly, whose reduced activity has been associated with both Parkinson's and late onset Alzheimer's disease.

View Article and Find Full Text PDF

Establishing with precision the quantity and identity of the cell types of the brain is a prerequisite for a detailed compendium of gene and protein expression in the central nervous system (CNS). Currently, however, strict quantitation of cell numbers has been achieved only for the nervous system of . Here, we describe the development of a synergistic pipeline of molecular genetic, imaging, and computational technologies designed to allow high-throughput, precise quantitation with cellular resolution of reporters of gene expression in intact whole tissues with complex cellular constitutions such as the brain.

View Article and Find Full Text PDF

The decline of neuronal synapses is an established feature of ageing accompanied by the diminishment of neuronal function, and in the motor system at least, a reduction of behavioural capacity. Here, we have investigated Drosophila motor neuron synaptic terminals during ageing. We observed cumulative fragmentation of presynaptic structures accompanied by diminishment of both evoked and miniature neurotransmission occurring in tandem with reduced motor ability.

View Article and Find Full Text PDF

Dry-snow slab avalanches result from crack propagation in a highly porous weak layer buried within a stratified and metastable snowpack. While our understanding of slab avalanche mechanisms improved with recent experimental and numerical advances, fundamental micro-mechanical processes remain poorly understood due to a lack of non-invasive monitoring techniques. Using a novel discrete micro-mechanical model, we reproduced crack propagation dynamics observed in field experiments, which employ the propagation saw test.

View Article and Find Full Text PDF

Genetic-optimised aperiodic code for distributed optical fibre sensors.

Nat Commun

November 2020

EPFL Swiss Federal Institute of Technology, Institute of Electrical Engineering, SCI STI LT, Station 11, CH-1015, Lausanne, Switzerland.

Distributed optical fibre sensors deliver a map of a physical quantity along an optical fibre, providing a unique solution for health monitoring of targeted structures. Considerable developments over recent years have pushed conventional distributed sensors towards their ultimate performance, while any significant improvement demands a substantial hardware overhead. Here, a technique is proposed, encoding the interrogating light signal by a single-sequence aperiodic code and spatially resolving the fibre information through a fast post-processing.

View Article and Find Full Text PDF

Porous brittle solids have the ability to collapse and fail even under compressive stresses. In fracture mechanics, this singular behavior, often referred to as anticrack, demands for appropriate continuum models to predict the catastrophic failure. To identify universal controls of anticracks, we link the microstructure of a porous solid with its yield surface at the onset of plastic flow.

View Article and Find Full Text PDF

Distributed forward Brillouin sensor based on local light phase recovery.

Nat Commun

July 2018

EPFL Swiss Federal Institute of Technology, Institute of Electrical Engineering, SCI-STI-LT Station 11, CH-1015, Lausanne, Switzerland.

The distributed fibre sensing technology based on backward stimulated Brillouin scattering (BSBS) is experiencing a rapid development. However, all reported implementations of distributed Brillouin fibre sensors until today are restricted to detecting physical parameters inside the fibre core. On the contrary, forward stimulated Brillouin scattering (FSBS), due to its resonating transverse acoustic waves, is being studied recently to facilitate innovative detections in the fibre surroundings, opening sensing domains that are impossible with BSBS.

View Article and Find Full Text PDF

Strain engineering is a widespread strategy used to enhance performance of devices based on semiconductor thin films. In ferroelectrics strain engineering is used to control the domain pattern: When an epitaxial film is biaxially compressed, e.g.

View Article and Find Full Text PDF

Conductive domain walls (DWs) in ferroic oxides as device elements are a highly attractive research topic because of their robust and agile response to electric field. Charged DWs possessing metallic-type conductivity hold the highest promises in this aspect. However, their intricate creation, low stability, and interference with nonconductive DWs hinder their investigation and the progress toward future applications.

View Article and Find Full Text PDF

In contrast to the flexible rotation of magnetization direction in ferromagnets, the spontaneous polarization in ferroelectric materials is highly confined along the symmetry-allowed directions. Accordingly, chirality at ferroelectric domain walls was treated only at the theoretical level and its real appearance is still a mystery. Here we report a Néel-like domain wall imaged by atom-resolved transmission electron microscopy in Ti-rich ferroelectric Pb(Zr1-xTix)O3 crystals, where nanometre-scale monoclinic order coexists with the tetragonal order.

View Article and Find Full Text PDF

Charged domain walls in ferroelectric materials are of high interest due to their potential use in nanoelectronic devices. While previous approaches have utilized complex scanning probe techniques or frustrative poling here we show the creation of charged domain walls in ferroelectric thin films during simple polarization switching using either a conductive probe tip or patterned top electrodes. We demonstrate that ferroelectric switching is accompanied - without exception - by the appearance of charged domain walls and that these walls can be displaced and erased reliably.

View Article and Find Full Text PDF

Distributed fiber sensing possesses the unique ability to measure the distributed profile of an environmental quantity along many tens of kilometers with spatial resolutions in the meter or even centimeter scale. This feature enables distributed sensors to provide a large number of resolved points using a single optical fiber. However, in current systems, this number has remained constrained to a few hundreds of thousands due to the finite signal-to-noise ratio (SNR) of the measurements, which imposes significant challenges in the development of more performing sensors.

View Article and Find Full Text PDF

Distributed optical fibre sensors possess the unique capability of measuring the spatial and temporal map of environmental quantities that can be of great interest for several field applications. Although existing methods for performance enhancement have enabled important progresses in the field, they do not take full advantage of all information present in the measured data, still giving room for substantial improvement over the state-of-the-art. Here we propose and experimentally demonstrate an approach for performance enhancement that exploits the high level of similitude and redundancy contained on the multidimensional information measured by distributed fibre sensors.

View Article and Find Full Text PDF

The velocity of individual 180° domain walls in thin ferroelectric films of PbZr0.1Ti0.9O3 is strongly dependent on the thickness of the top Pt electrode made by electron-beam induced deposition (EBID).

View Article and Find Full Text PDF

Use of ferroelectric domain-walls in future electronics requires that they are stable, rewritable conducting channels. Here we demonstrate nonthermally activated metallic-like conduction in nominally uncharged, bent, rewritable ferroelectric-ferroelastic domain-walls of the ubiquitous ferroelectric Pb(Zr,Ti)O3 using scanning force microscopy down to a temperature of 4 K. New walls created at 4 K by pressure exhibit similar robust and intrinsic conductivity.

View Article and Find Full Text PDF

Charged domain walls in proper ferroelectrics were shown recently to possess metallic-like conductivity. Unlike conventional heterointerfaces, these walls can be displaced inside a dielectric by an electric field, which is of interest for future electronic circuitry. In addition, theory predicts that charged domain walls may influence the electromechanical response of ferroelectrics, with strong enhancement upon increased charged domain wall density.

View Article and Find Full Text PDF

Impurity elements used as dopants are essential to semiconductor technology for controlling the concentration of charge carriers. Their location in the semiconductor crystal is determined during the fabrication process and remains fixed. However, another possibility exists whereby the concentration of charge carriers is modified using polarization charge as a quasi-dopant, which implies the possibility to write, displace, erase and re-create channels having a metallic-type conductivity inside a wide-bandgap semiconductor matrix.

View Article and Find Full Text PDF

Domain walls in ferroic materials have attracted significant interest in recent years, in particular because of the unique properties that can be found in their vicinity. However, to fully harness their potential as nanoscale functional entities, it is essential to achieve reliable and precise control of their nucleation, location, number and velocity. Here, using piezoresponse force microscopy, we show the control and manipulation of domain walls in ferroelectric thin films of Pb(Zr,Ti)O₃ with Pt top electrodes.

View Article and Find Full Text PDF

Sinc-shaped Nyquist pulses possess a rectangular spectrum, enabling data to be encoded in a minimum spectral bandwidth and satisfying by essence the Nyquist criterion of zero inter-symbol interference (ISI). This property makes them very attractive for communication systems since data transmission rates can be maximized while the bandwidth usage is minimized. However, most of the pulse-shaping methods reported so far have remained rather complex and none has led to ideal sinc pulses.

View Article and Find Full Text PDF

Bipolar optical pulse coding for performance enhancement in BOTDA sensors.

Opt Express

July 2013

EPFL Swiss Federal Institute of Technology, Institute of Electrical Engineering, SCI-STI-LT, Station 11, CH-1015Lausanne, Switzerland.

A pump signal based on bipolar pulse coding and single-sideband suppressed-carried (SSB-SC) modulation is proposed for Brillouin optical time-domain analysis (BOTDA) sensors. Making a sequential use of the Brillouin gain and loss spectra, the technique is experimentally validated using bipolar complementary-correlation Golay codes along a 100 km-long fiber and 2 m spatial resolution, fully resolving a 2 m hot-spot at the end of the sensing fiber with no distortion introduced by the decoding algorithm. Experimental results, in good agreement with the theory, indicate that bipolar Golay codes provide a higher signal-to-noise ratio enhancement and stronger robustness to pump depletion in comparison to optimum unipolar pulse codes known for BOTDA sensing.

View Article and Find Full Text PDF