1 results match your criteria: "EA4421 SiGReTO Nancy University[Affiliation]"
PLoS One
May 2012
EA4421 SiGReTO Nancy University, Faculty of Medicine, Vandoeuvre-lès-Nancy, France.
Purpose: Beside its efficacy in cancer treatment, radiotherapy induces degeneration of healthy tissues within the irradiated area. The aim of this study was to analyze the variations of proinflammatory (IL-1α, IL-2, IL-6, TNF-α, IFN-γ), profibrotic (TGF-β1), proangiogneic (VEGF) and stem cell mobilizing (GM-CSF) cytokines and growth factors in an animal model of radiation-induced tissue degeneration.
Materials And Methods: 24 rats were irradiated unilaterally on the hindlimb at a monodose of 30 Gy.