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Role of exosite binding modulators in the inhibition of Fxa by TFPI.
Thromb Haemost
March 2016
Stella Thomassen, Department of Biochemistry, Cardiovascular Research Institute Maastricht, University Maastricht, 6200 MD Maastricht, the Netherlands, Tel.: +31 43 388 4160, Fax: +31 43 388 4159, E-mail:
Tissue factor pathway inhibitor (TFPI) down-regulates the extrinsic coagulation pathway by inhibiting FXa and FVIIa. Both TFPI and FXa interact with several plasma proteins (e. g.
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