1,404 results match your criteria: "Durham Veterans Affairs Medical Center.[Affiliation]"

Importance: Clinical productivity measures may incentivize clinical care to specific patient populations and thus perpetuate inequitable care. Before the 2021 Medicare physician fee schedule changes, outpatient dermatology encounters for patients who were younger, female, and races other than White systematically generated fewer work relative value units (wRVUs).

Objective: To examine the association of patient race, age, and sex with wRVUs generated by outpatient dermatology encounters after 2021.

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Background: Acute lower respiratory tract infections (ALRIs) remain the leading infectious cause of death among children < 5 years, with viruses contributing to a large proportion of cases. Little is known about the epidemiology and etiology of viral ALRI in rural Bangladesh.

Methods: We enrolled 3- to 23-month-old children with ALRIs attending a subdistrict hospital outpatient clinic in Sylhet district in Bangladesh.

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Article Synopsis
  • The study investigated how different eating disorders (like anorexia and bulimia) vary in terms of symptoms related to anxiety, OCD, and depression upon treatment admission.
  • It included a sample of 3,730 adults and found that symptom patterns varied by disorder, with anorexia and avoidant/restrictive disorders showing more anxiety and OCD symptoms, while binge eating disorder had more depressive symptoms.
  • Overall, all patients, especially those with ARFID and binge eating disorder, showed significant improvement in their symptoms after treatment, although some groups had higher initial severity compared to others.
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Introduction: Multimorbidity is associated with lower physical function in older adults. Less is known about multimorbidity and physical activity earlier in the life course. This study examined multimorbidity trajectories across adulthood with physical activity and explores if multimorbidity accelerates age-related activity decline.

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Background: Higher level of care (HLOC) treatment for eating disorders (EDs) is sometimes necessary, but research is lacking on whether HLOCs are actually more effective than less structured, lower levels of care. The purpose of the current study was to compare outcomes for patients with EDs at low weights who entered 24/7 care (inpatient and residential) to those entering non-24/7 care (partial hospitalization programming and intensive outpatient programming).

Methods: Participants were 1104 adults with body mass indices (BMI) between 14 and 17 receiving treatment for an ED at a large multisite treatment facility offering HLOCs between August 2019 and February 2024.

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Enteral and Parenteral Nutrition Timing in eICU Collaborative Research Database by Race: A Retrospective Observational Study.

J Surg Res

December 2024

Division of Trauma, Acute, and Critical Care Surgery, Department of Surgery, Duke University, Durham, North Carolina. Electronic address:

Introduction: Racial and ethnic disparities in malnutrition are well-known, but it is unknown if there are disparities in early nutrition delivery for intensive care unit (ICU) patients, which is associated with better outcomes. We investigated the timing of enteral nutrition (EN) and parenteral nutrition (PN) initiation in the ICU, examining for racial differences.

Methods: Using the eICU-Collaborative Research Database (eICU-CRD) from 2014 to 2015, we analyzed patients eligible for EN and PN from 208 hospitals.

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Lessons on Telemedicine in Rheumatology: Thinking beyond the Coronavirus Disease 2019 Pandemic.

Rheum Dis Clin North Am

February 2025

Rheumatology Fellowship Training Program, Division of Rheumatology, Allergy, and Immunology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA. Electronic address:

During the COVID-19 pandemic, telemedicine was rapidly deployed to meet the clinical needs of patients with rheumatic diseases worldwide. Rheumatologists were forced to care for patients with all rheumatic diseases, regardless of disease activity, and limited evidence was available to guide provider decision-making regarding telemedicine appropriateness for outpatient rheumatology encounters. As the COVID-19 pandemic progressed, the ongoing provision of rheumatology telemedicine care in the U.

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Background: Community-acquired acute kidney injury (CA-AKI) occurs outside of the hospital and is the most common form of AKI. CA-AKI is not well understood, which hinders efforts to prevent, identify, and manage CA-AKI.

Objective: Examine 30-day outcomes following CA-AKI using national administrative and lab data from the Veterans Health Administration (VA).

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Background: With more than 15,000 annual deaths from head and neck cancer (HNC), an important aspect of end-of-life care for these patients is place of death. Recent evidence suggests an increasing preference for home/hospice at end of life; however, it is unclear whether there is variation in home/hospice use based on region or urban status. We described differences in the place of death of HNC patients based on their region and urban status.

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This article is a summary of the first AGS Symposium entitled "Update on Vaccination Strategies for Older Adults: Matching the Approach to the Individual and the Care Setting." Given declines in host defenses and immune function with aging, vaccinations play a pivotal role in fortifying older adults against preventable infections, resulting diseases, disability, and death. Current guidelines generally list recommendations applicable for an average older adult of a given chronological age.

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Non-Hispanic Black patients diagnosed with prostate cancer between 2014 and 2019 and treated at a comprehensive cancer center were less likely to use tumor-specific genomic testing compared with non-Hispanic White patients. Disparities in the use of precision oncology technologies should be monitored and addressed to ensure equitable cancer care.

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Background: Despite widespread use of higher levels of care in treating eating disorders in adolescents, research supporting the use of these treatments remains limited by small sample sizes and a predominant focus on anorexia nervosa. Further, existing data regarding predictors of outcome have yielded mixed findings. In the current study, we evaluated treatment outcomes and predictors of outcome among a large sample of adolescents with eating disorders presenting to inpatient, residential, partial hospitalization programs, and intensive outpatient programs across the United States.

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Article Synopsis
  • * A 2019 analysis revealed that nearly half of North Carolina's dual-eligible population was eligible for Medicare due to disability, with a significant portion losing full Medicaid benefits at some point. Most beneficiaries were in traditional fee-for-service Medicaid, while enrollment in specialized plans like D-SNPs has risen notably.
  • * The integration of Medicare and Medicaid is seen as a key strategy to improve care value for dual-eligible beneficiaries, supporting the overall goals of NC Medicaid transformation and minimizing service disruption.
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Harnessing the host response for precision infectious disease diagnosis.

Clin Microbiol Rev

December 2024

Department of Medicine, Center for Infectious Disease Diagnostics and Innovation, Duke University, Durham, North Carolina, USA.

Article Synopsis
  • Accurate detection of infections and their causes is crucial for effective antibiotic treatment, but traditional methods often fall short due to limitations in pathogen-focused diagnostics.* -
  • Understanding the human immune response to different pathogens can lead to better diagnostic options, especially in critical illnesses and cases of diagnostic uncertainty.* -
  • This review highlights the advantages of host response-based diagnostics, discusses existing and upcoming tests, and identifies opportunities for future innovations in this area.*
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  • The study aimed to evaluate how systemic lupus erythematosus (SLE) affects people's ability to perform daily activities independently, specifically instrumental and basic activities of daily living (IADLs and BADLs).
  • The research involved 436 participants, primarily female and Black, with over half reporting difficulties in IADLs like housekeeping and shopping, and significant limitations in BADLs such as bathing and dressing.
  • Results indicated that higher disease activity, along with factors like depression, stress, lower income, and older age, strongly correlated with limitations in daily activities, highlighting the need for strategies to improve quality of life for older individuals with SLE.
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  • The study examines the effects of prescribing multiple psychoactive medications, specifically gabapentinoids alongside other potentially inappropriate medications (PPIMs), in patients undergoing dialysis.
  • It found that coprescribing these medications significantly increases the risk of altered mental status (AMS) and falls, especially in patients with varying levels of frailty.
  • Results indicate that frailty influences the severity of these risks, with the highest hazard for AMS and falls observed in patients with severe frailty receiving multiple psychoactive prescriptions.
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A subset of patients with chronic hepatitis C virus (HCV) infection demonstrate liver enzyme elevation (LEE) after achieving sustained virologic response (SVR). Risk factors for LEE are not well characterised. We conducted a single-centre retrospective cohort study of adults with HCV infection in the Duke University Health System who received direct-acting antiviral therapy and achieved SVR.

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Long-term Monitoring of Blood Pressure in Older Adults: A Focus on Self-Measured Blood Pressure Monitoring.

Clin Geriatr Med

November 2024

Durham Veterans Affairs Geriatric Research Education and Clinical Center, Durham Veterans Affairs Medical Center (VAMC), 508 Fulton Street, Durham, NC 27705, USA.

Hypertension is among the most common chronic conditions in older adults. Effective treatment exists, yet many older adults do not achieve recommended control of their blood pressure (BP). Self-measured blood pressure (SMBP) monitoring, in which patients check their BP at home, is one underutilized tool for improving hypertension control.

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Article Synopsis
  • The Type 1 and 2 systemic lupus erythematosus (SLE) Model aims to capture all symptoms experienced by SLE patients and is based on prior qualitative research reflecting their lived experiences.
  • A qualitative study involving 13 rheumatologists was conducted to gather their feedback on the model's relevance to their clinical practice, with most expressing approval and finding it helpful for treatment and patient education.
  • While the model was generally well-received, some rheumatologists raised concerns about its potential to contribute to overdiagnosis of SLE, highlighting the need for further research on its effects on patient interactions and outcomes.
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Emergency department discharges directly to hospice: Longitudinal assessment of a streamlined referral program.

Am J Emerg Med

December 2024

UNC Palliative Care and Hospice Program, University of North Carolina at Chapel Hill School of Medicine, 101 Manning Drive, Chapel Hill, NC 27514, USA; Department of Psychiatry, University of North Carolina at Chapel Hill School of Medicine, 101 Manning Drive, Chapel Hill, NC 27514, USA. Electronic address:

Introduction: 80 % of Americans wish to die somewhere other than a hospital, and hospice is an essential resource for providing such care. The emergency department (ED) is an important location for identifying patients with end-of-life care needs and providing access to hospice. The objective of this study was to analyze a quality improvement (QI) program designed to increase the number of patients referred directly to hospice from the ED, without the need for an observation stay and without access to in-hospital hospice.

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AGA Clinical Practice Update on Integrating Potassium-Competitive Acid Blockers Into Clinical Practice: Expert Review.

Gastroenterology

November 2024

Division of Gastroenterology, Chinese University of Hong Kong, Hong Kong Special Administrative Region, The People's Republic of China.

Description: The purpose of this American Gastroenterological Association (AGA) Institute Clinical Practice Update (CPU) is to summarize the available evidence and offer expert Best Practice Advice on the integration of potassium-competitive acid blockers (P-CABs) in the clinical management of foregut disorders, specifically including gastroesophageal reflux disease, Helicobacter pylori infection, and peptic ulcer disease.

Methods: This expert review was commissioned and approved by the AGA Institute Governing Board and CPU Committee to provide timely guidance on a topic of high clinical importance to the AGA membership. This CPU expert review underwent internal peer review by the CPU Committee and external peer review through the standard procedures of Gastroenterology.

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Background: Approximately 10-15 % of individuals with type 2 diabetes have persistently poorly-controlled diabetes mellitus (PPDM) despite receiving available care, and frequently have comorbid hypertension. Mobile monitoring-enabled telehealth has the potential to improve outcomes in treatment-resistant chronic disease by supporting self-management and facilitating patient-clinician contact but must be designed in a manner amenable to real-world use.

Methods: Expanding Technology-Enabled, Nurse-Delivered Chronic Disease Care (EXTEND) is an ongoing randomized trial comparing two 12-month interventions for comorbid PPDM and hypertension: 1) EXTEND, a mobile monitoring-enabled self-management intervention; and 2) EXTEND Plus, a comprehensive, nurse-delivered telehealth program incorporating mobile monitoring, self-management support, and pharmacist-supported medication management.

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Eating disorders (EDs) have historically been thought of as afflictions of younger women, but EDs do occur in midlife/older adults, and the incidence of EDs among older women may be increasing. The present study sought to examine outcomes for patients with anorexia nervosa needing to weight restore across four age groups: under 18, 18-25, 26-39, and 40+. Based on prior research, it was hypothesized that there would be no differences between the age groups in percent of expected body weight (%EBW) gained during treatment.

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Primary dermal melanoma (PDM) is a rare variant of melanoma. We present the case of a 76-year-old female diagnosed with PDM following initial suspicion of basal cell carcinoma, prompting extensive workup to exclude metastasis. This case demonstrates the diagnostic challenges and need for rigorous evaluation in suspected PDM cases.

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