3 results match your criteria: "Durham Veterans Affairs Center of Innovation to Accelerate Discovery and Practice Change (ADAPT).[Affiliation]"

Background: Illuminating heterogeneity of treatment effect (HTE) within trials is important for identifying target populations for implementation.

Objective: The aim of this study was to examine HTE in a trial of group medical visits (GMVs) for patients with type 2 diabetes and elevated body mass index.

Research Design And Measures: Participants (n=263) were randomized to GMV-based medication management plus low carbohydrate diet-focused weight management (WM/GMV; n=127) or GMV-based medication management alone (GMV; n=136) for diabetes control.

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Practical telehealth to improve control and engagement for patients with clinic-refractory diabetes mellitus (PRACTICE-DM): Protocol and baseline data for a randomized trial.

Contemp Clin Trials

November 2020

Durham Veterans Affairs Center of Innovation to Accelerate Discovery and Practice Change (ADAPT), Durham, NC, United States of America; Division of Endocrinology, Department of Medicine, Duke University School of Medicine, Durham, NC, United States of America. Electronic address:

Background: Persistent poorly-controlled type 2 diabetes mellitus (PPDM), or maintenance of a hemoglobin A1c (HbA1c) ≥8.5% despite receiving clinic-based diabetes care, contributes disproportionately to the national diabetes burden. Comprehensive telehealth interventions may help ameliorate PPDM, but existing approaches have rarely been designed with clinical implementation in mind, limiting use in routine practice.

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Article Synopsis
  • African Americans have higher rates of diabetes and related conditions, leading to greater risk of kidney function decline compared to non-African Americans.
  • A study analyzed the effects of a pharmacist-led telehealth intervention on kidney function in 281 primary care patients, with a focus on how responses differed between African Americans and non-African Americans.
  • Results indicated that African Americans in the intervention group experienced better preservation of kidney function, while non-African Americans experienced a greater decline, suggesting the intervention was more effective for African Americans.
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