34,986 results match your criteria: "Duodenal Ulcers"

Background: Polyarteritis nodosa is a relatively uncommon type of systemic necrotizing vasculitis that primarily affects medium-sized arteries. While gastrointestinal involvement is known in polyarteritis nodosa, heavy gastrointestinal bleeding due to gastric ulceration is relatively uncommon. We present the case of an 81-year-old male of Chinese ethnicity who experienced severe gastrointestinal bleeding as a result of polyarteritis nodosa and an innovative treatment approach for a better patient outcomes.

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Background: The Rome IV criteria offer symptom-based recommendations for diagnosing functional gastrointestinal diseases (FGID) in children and adolescents without esophagogastroduodenoscopy (EGD). The aim of this study is to evaluate the usefulness of Rome IV criteria for ruling out organic disease in patients with and without alarm symptoms.

Methods: Retrospective research was conducted on children and adolescents who had dyspepsia and underwent EGD.

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In this editorial we comment on the article by Wang , recently published on . Acute non-variceal upper gastrointestinal bleeding (ANVUGIB) represents a common and potentially serious gastroenterological emergency. Wang conducted a detailed study on the management of ANVUGIB in a high-volume center in the Shaanxi region, China.

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Gallium-Fibroblast activation protein inhibitor (Ga-FAPI) positron emission tomography/computed tomography (PET/CT) is increasingly used for evaluating various epithelial neoplasms. Despite addressing some pitfalls, many remain unacknowledged. This report details a 77-year-old man with suspected pancreatic malignancy who underwent a Ga-FAPI PET/CT scan post-gastroduodenal coil embolization for upper gastrointestinal bleeding.

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Background: In April 2024, our hospital confirmed a rare case of intra-abdominal infection by Kodamaea ohmeri. The patient sought medical attention at our hospital after taking painkillers orally for one month, experiencing recurrent abdominal pain for 17 days and worsening for 7 days. In March 2024, the patient received symptomatic treatment with oral analgesics (diclofenac sodium) for arthritis.

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miR-137 regulates autophagy and apoptosis in duodenal ulcer by targeting BNIP3L.

Medicine (Baltimore)

December 2024

Department of Gastroenterology, Shijiazhuang People's Hospital, Hebei Medical University, Shijiazhuang, Hebei, China.

Article Synopsis
  • Duodenal ulcers (DU) occur when the duodenum’s lining is damaged, and this study focuses on the role of microRNA-137 (miR-137) in DU progression, particularly its effects on autophagy and apoptosis.
  • Analysis identified miR-137 as significantly dysregulated and confirmed that it targets the gene BNIP3L, affecting cellular processes in duodenal epithelial cells.
  • Upregulation of miR-137 leads to decreased BNIP3L expression, hindered autophagy, and increased cell apoptosis, suggesting that targeting miR-137 could offer a new approach for treating duodenal ulcers.*
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Association of leukocyte telomere length with the risk of digestive diseases: A large-scale cohort study.

Chin Med J (Engl)

December 2024

The Secondary Department of Hepatobiliary and Pancreatic Surgery, General Surgery Center, First Hospital of Jilin University, Changchun, Jilin 130021, China.

Article Synopsis
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Objectives: The aim of this study was to investigate the surgical treatment methods and outcomes of difficult duodenal defects due to perforation.

Material And Methods: Data of patients who had undergone surgery for difficult duodenal defect between January 2012 and November 2022 were collected. Duodenal defect size of 2 cm or more was defined as difficult duodenal defect.

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Genetic insights into the gut microbiota-duodenal diseases interplay: A Mendelian randomization and Bayesian weighting study.

Microb Pathog

November 2024

The Second Affiliated Hospital, School of Ocean and Tropical Medicine, Guangdong Medical University, Zhanjiang, China. Electronic address:

Article Synopsis
  • Many studies indicate a strong link between gut microbiota and duodenal diseases, prompting this research to investigate potential causal relationships, particularly with duodenal ulcers and duodenitis.
  • Using Mendelian randomization (MR) methods and genetic data from various health databases, the researchers analyzed how different gut microbiota affect the occurrence of duodenal diseases.
  • The findings revealed specific gut microbiota that both promote duodenal ulcers and affect duodenitis, while also suggesting that the presence of duodenal ulcers may encourage the growth of certain harmful microbiota.
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Chronic pyloric obstruction caused by Flammulina mushroom: A rare case report.

Medicine (Baltimore)

November 2024

Department of Gastroenterology, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, Shenzhen, China.

Article Synopsis
  • A man in his early 30s experienced chronic pyloric obstruction for 4 years, presenting with recurrent vomiting, ultimately linked to a blockage caused by a Flammulina mushroom.
  • Diagnostic imaging and lab tests indicated gastric issues, leading to an endoscopic procedure where the foreign object was identified and removed.
  • post-removal, the patient experienced complete resolution of symptoms, highlighting the need for thorough diagnostics in similar cases where obstructions may not follow typical patterns.
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Small bowel obstruction secondary to impacted pancreatic necrosum through a spontaneous duodenal fistula: a first in the literature.

J Surg Case Rep

November 2024

Department of Surgery, Western University, London Health Sciences Centre, Victoria Hospital, 800 Commissioners Rd., Rm E4-112 London, ON N6A 5W9, Canada.

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A rare case of endoscopic visualization of a metallic coil in a duodenal ulcer after transcatheter arterial embolization.

Oxf Med Case Reports

November 2024

Department of Medicine, Section of Digestive Diseases, Yale School of Medicine, 333 Cedar St, New Haven, CT 06510, United States.

Transcatheter arterial embolization is the therapy of choice for recurrent peptic ulcer bleeding refractory to standard endoscopic hemostatic techniques. It offers a minimally invasive approach with high efficacy, lower mortality, and complication rates compared to surgery. However, rare adverse events attributed to coil migration including pulmonary embolism, stroke, myocardial infarction, and bowel obstruction have been reported.

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Unlabelled: Helicobacter pylori (Hp) infection plays an important role in the genesis of peptic ulcer disease. In the absence of susceptibility testing, concomitant quadruple therapy is one of the most widely used eradication methods. In the absence of a study on four-drug therapy and the difficulty of studying antibiotic susceptibility in our context, we initiated this work in order to evaluate the efficacy of an empirical treatment with concomitant four-drug therapy currently available.

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Massive upper gastrointestinal bleeding still remains a challenge, which can cause serious clinical problems especially in high-risk patients. We present a rare case of patient with complex pathology successfully managed by endovascular treatment. A 78-year-old man with a medical history of chronic bronchitis, several minor strokes, type II diabetes, a 30-year history of smoking, and a family history of cardiovascular disease, presented with severe pain on the left side of his chest radiating to his left arm.

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Behçet's disease (BD) is characterized by skin lesions, uveitis, and recurrent oral and genital ulcers. Vascular problems, predominantly affecting veins, lead to thrombosis, increasing the risk of ruptured artery aneurysms and Budd-Chiari syndrome (BCS). Morbidity and mortality are significantly heightened by rare occurrences such as pulmonary artery aneurysms, cardiac involvement, and BCS.

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Prevalence of common upper gastrointestinal diseases in Chinese adults aged 18-64 years.

Sci Bull (Beijing)

December 2024

Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China. Electronic address:

Article Synopsis
  • A community-based study was conducted in China to assess the prevalence of GERD, reflux esophagitis, gastric and duodenal ulcers, as well as Helicobacter pylori infection among adults aged 18-64, involving 27,637 participants from 2017 to 2018.
  • The study found prevalence rates of 10.5% for GERD, 5.4% for reflux esophagitis, 2.5% for gastric ulcers, 4.5% for duodenal ulcers, and 41.5% for H. pylori infection, with specific regions showing varying rates.
  • Common risk factors identified for GERD, reflux esophagitis, and gastric ulcers included
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ABO Blood Group and Auditory Function in Young Adults.

Indian J Otolaryngol Head Neck Surg

December 2024

Department of Audiology and Speech Language Pathology, AWH Special college, Kallai, Calicut, Kerala India.

Introduction: In recent years, research on the effect of blood group on hearing function has gained more attention. Some blood groups show susceptibility to certain general health and auditory disorders like noise induced hearing loss, infections, coronary artery disease, gastric carcinoma and duodenal ulcer.

Aims: The present study aimed to determine the differences in middle ear and cochlear function among persons with different blood groups (AB, A, B, O).

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Foregut tuberculosis: Too close but miles apart.

World J Clin Cases

November 2024

Department of Medicine, Section of Gastroenterology, Aga Khan University Hospital, Karachi 74800, Pakistan.

Article Synopsis
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Article Synopsis
  • Acute esophageal necrosis (AEN) is a rare and serious condition marked by black discoloration in the esophagus, often triggered by major stressors like trauma or surgeries, with a mortality rate up to 32%.
  • Patients with AEN typically have risk factors such as diabetes, hypertension, and kidney disease, but it can also occur in healthy individuals after surgery.
  • Early diagnosis through upper endoscopy and supportive care is crucial to manage AEN effectively and reduce the risk of severe complications.
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