2,620 results match your criteria: "Dumping Syndrome"

Background: Oesophago-gastric cancer surgery negatively affects quality of life with a high postoperative symptom burden. Several conditions that may be diagnosed and treated after surgery are recognised. However, consensus regarding their definition and management is lacking.

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Article Synopsis
  • Diabetes mellitus (DM) is a condition marked by high blood sugar levels due to inadequate insulin production, requiring patients to undergo long-term treatment with existing hypoglycemic drugs, which are often ineffective for managing the disease.
  • Traditional weight loss surgeries, like gastric bypass, have strict BMI requirements and can lead to complications such as hypoglycemia and dumping syndrome, reducing their effectiveness for DM treatment.
  • Jejunoileostomy is a newer surgical option showing promise for improving glucose and lipid metabolism without altering the gastrointestinal structure, resulting in fewer complications and better management of DM-related issues, supported by clinical consensus on its surgical and postoperative management.
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Article Synopsis
  • Obesity is a major health issue, and metabolic bariatric surgery (MBS) like Roux-en-Y gastric bypass (RYGB) is a common treatment for obesity-related type 2 diabetes mellitus (T2DM), despite potential complications.
  • A case study of a 52-year-old woman highlights the risks of RYGB, including severe weight loss and electrolyte imbalances, leading to the decision for a complex reversal surgery.
  • The reversal of RYGB requires careful patient selection and preoperative management, with a collaborative approach involving various healthcare professionals for optimal outcomes.
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Dumping syndrome: Update on pathophysiology, diagnosis, and management.

Neurogastroenterol Motil

November 2024

Translational Research Center for Gastrointestinal Diseases (TARGID), University of Leuven, Leuven, Belgium.

Article Synopsis
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Article Synopsis
  • - Post-bariatric surgery hypoglycemia, also called late dumping syndrome, is a challenging condition caused by various factors like surgery changes, hormone adjustments, and hidden health issues, requiring a team approach for treatment.
  • - A case study of a 36-year-old nurse showed she had ongoing hypoglycemia after gastric sleeve surgery, leading to the discovery of an autoimmune disorder called latent autoimmune diabetes in adults (LADA).
  • - The patient's treatment was updated to include insulin and a new drug, teplizumab, to manage her diabetes, highlighting the need for detailed evaluations and teamwork among healthcare professionals to improve patient outcomes after bariatric surgery.
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Purpose: Dumping syndrome (DS) is a common complication of metabolic surgery, occurring in as many as 40% of bariatric patients. The reference diagnostic test is oral glucose tolerance testing (OGTT) which is often poorly tolerated and may induce false positive results. Continuous glucose monitoring (CGM) is better tolerated and can monitor patients for about 2 weeks in everyday life.

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Waste management and disease spread potential: A case study of SARS-CoV-2 in garbage dumping sites in Bangkok and its vicinity.

One Health

December 2024

The Monitoring and Surveillance Center for Zoonotic Diseases in Wildlife and Exotic Animals, Faculty of Veterinary Science, Mahidol University, Salaya, Nakhon Pathom, Thailand.

Article Synopsis
  • - During the COVID-19 pandemic, personal protective equipment (PPE) like masks and gloves were disposed of improperly at garbage dumping sites, leading to potential environmental contamination.
  • - A study conducted in Thailand found that while most samples from animals and other environmental sources did not show SARS-CoV-2, two face masks collected from a dumping site tested positive for the virus, indicating a risk of transmission through waste.
  • - The findings emphasize the importance of effective waste management practices and the need for proper PPE for waste handling personnel to minimize exposure and prevent further spread of viruses.
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Article Synopsis
  • The study aimed to compare the long-term outcomes of laparoscopic pylorus preserving gastrectomy (LPPG) and laparoscopic distal gastrectomy (LDG) for treating early gastric cancer (EGC) in a multicenter randomized controlled trial with 256 patients.
  • Results showed no significant difference in the incidence of dumping syndrome after one year (13.2% for LPPG vs. 15.8% for LDG), but LPPG had lower rates of gallstone formation and better preservation of hemoglobin and serum protein levels.
  • While LPPG had more instances of reflux esophagitis and delayed gastric emptying, overall survival and quality of life after three years were similar between the two
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Article Synopsis
  • Dumping syndrome (DS) is a combination of GI and vasomotor symptoms that occur after eating, often due to rapid gastric emptying from surgical changes.
  • Bariatric surgery, especially Roux-en-Y gastric bypass (RYGB), is the leading cause of DS, with 25-50% of gastric surgery patients experiencing symptoms.
  • This review aims to explore current literature on DS, focusing on diagnosis, causes, terminology, and treatment, highlighting the need for further research to create effective management guidelines.
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Nutrition and Patient Follow-up in Bariatric Surgery.

Eurasian J Med

December 2023

Department of General Surgery, Kafkas University Faculty of Medicine, Kars,Turkey.

Obesity and obesity-related diseases may emerge as a major public health issue in the near future. There are several efective methods to prevent obesity, such as diet, sports, and pharmacotherapy. However, these methods provide temporary weight loss.

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Predictors and weight impact of postbariatric hypoglycemia after Roux-en-Y gastric bypass surgery: a prospective observational cohort study.

Surg Obes Relat Dis

December 2024

Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland; Service of Endocrinology, Diabetes and Metabolism, Lausanne University Hospital, Lausanne, Switzerland. Electronic address:

Article Synopsis
  • Postbariatric hypoglycemia (PBH) is a common condition affecting quality of life in patients after Roux-en-Y gastric bypass surgery, with a 32% incidence rate found in a study of 222 patients.
  • Younger age at surgery and experiencing early dumping syndrome are significant predictors of PBH, while higher glucose levels at 2 hours during an oral glucose tolerance test (OGTT) indicate a lower risk.
  • The study found no correlation between PBH and weight changes after surgery, highlighting the complexity of its impact on patients' health outcomes.
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Article Synopsis
  • The study aimed to determine the prevalence of dumping syndrome after esophageal cancer surgery, which has been inconsistently reported in previous research.
  • After reviewing nearly 3,000 articles, 16 were included in the analysis, revealing a pooled prevalence of 27%, with significant variability among studies.
  • The findings suggest that using specific questionnaires to measure dumping syndrome can lead to more consistent results and better understanding in future research.
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Article Synopsis
  • The Japanese Guidelines for the Treatment of Gastric Cancer recommend proximal gastrectomy for early upper gastric cancer patients who retain part of the stomach; however, recent studies suggest these guidelines may be too restrictive.
  • This meta-analysis examined both early and advanced gastric cancer patients, using only high-quality clinical studies to compare postoperative outcomes after proximal gastrectomy and total gastrectomy.
  • The analysis focused on various complications, quality of life, nutritional status, and oncologic outcomes, utilizing data from multiple medical databases up to June 2023.
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Article Synopsis
  • Postprandial hypoglycemia linked to Dumping Syndrome can occur after bariatric surgery, leading to severe symptoms a few hours post-meal.
  • A case study of a 31-year-old female who underwent gastric bypass surgery 10 years ago showed that semaglutide effectively reduced her hypoglycemic episodes after other treatments failed.
  • Semaglutide led to a significant decrease in blood glucose levels below 70 mg/dl, improving her glycemic control and quality of life for up to 8 months.
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Banded versus non-banded Roux-en-Y gastric bypass: short, mid, and long-term surgical outcomes - a systematic review and meta-analysis.

Surg Obes Relat Dis

September 2024

Centre Hospitalier Universitaire de Nice - Digestive Surgery and Liver Transplantation Unit, Archet 2 Hospital, Nice, France; Université Côte d'Azur, Nice, France; Inserm, U1065, Team 8 "Hepatic Complications of Obesity and Alcohol" Nice, France. Electronic address:

Article Synopsis
  • The Roux-en-Y gastric bypass (RYGB) is an effective obesity treatment, and a variant called banded-RYGB may offer advantages like better weight loss and fewer complications.
  • The meta-analysis included 13 studies with over 8,500 patients comparing outcomes between banded-RYGB and standard RYGB.
  • Results indicated that banded-RYGB led to significantly higher excess weight loss at 1, 2, and 5 years post-surgery, although the difference in postoperative complications was not statistically significant.
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Recurrent Hypoglycemia After Total Gastrectomy: A Case Report and Literature Analysis.

Am J Case Rep

June 2024

Department of Endocrinology, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Shandong Provincial Key Laboratory of Endocrinology and Lipid Metabolism, Jinan, Shandong, China (mainland).

Article Synopsis
  • Hypoglycemia is a frequent issue after total gastrectomy, often linked to dumping syndrome and malnutrition, but insulinoma should also be considered, especially for recurrent cases that can lead to severe health risks.
  • A 36-year-old woman experienced severe hypoglycemia and seizures four months post-gastrectomy for gastric cancer, which was ultimately diagnosed as insulinoma after various tests and imaging.
  • The report emphasizes the need for thorough evaluation of hypoglycemia after total gastrectomy and suggests that changes in the gastrointestinal tract may increase the risk of developing insulinomas, contributing to existing knowledge on this condition.
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Article Synopsis
  • The study compared the clinical effectiveness and patient quality of life between two surgical techniques, B-IIB (Billroth-II with Braun anastomosis) and B-II (Billroth-II anastomosis), in patients undergoing laparoscopic surgery for gastric cancer.
  • Data from 158 patients over a span of 6 years showed that those who had the B-IIB procedure had significantly shorter post-operative hospital stays and quicker recovery times compared to the B-II group.
  • Additionally, the B-IIB group exhibited fewer complications, less weight loss after surgery, and improved scores on post-surgery quality of life assessments related to symptoms like esophageal reflux and dyspepsia.
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Article Synopsis
  • The study aimed to compare the postoperative quality of life (QOL) and body weight changes between two types of gastrectomies: pylorus-preserving gastrectomy (PPG) and distal gastrectomy (DG) for Stage I gastric cancer.
  • Conducted on 295 patients, the research utilized questionnaires to assess QOL and found that DG had better scores for nausea, vomiting, and meal-related issues in the first month after surgery.
  • Ultimately, the study concluded there was no significant difference in long-term QOL or body weight loss between the two surgical methods.
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