Application of core-shell magnetic metal-organic framework in developing dispersive micro solid phase extraction combined with dispersive liquid-liquid microextraction for the extraction and enrichment of some pesticides in orange blossom, Aloysia Citrodora, and fennel herbal infusions.

This paper introduces an innovative technique for extracting pesticides from herbal infusions using a core-shell magnetic adsorbent (i.e., Cu-BTC@FeO) where achieving a notable enrichment factor for the target pesticides by coupling with a dispersive liquid-liquid microextraction method.

Dispersive solid phase extraction of apixaban from human plasma samples prior to capillary electrophoresis determination using zirconium-based metal organic frameworks prepared by different modulator and solvent.

Here, a zirconium-based metal organic framework-dispersive solid phase extraction method was established as an efficient, robust, and accurate approach for quantifying apixabanin human plasma samples prior to capillary electrophoresis with diode array detection. Various types of metal organic frameworks based on UiO-66-NH were synthesized by altering modulators and solvents and applied as sorbents in the extraction procedure. Among the tested sorbents, UiO-66-NH prepared in dimethylformamide in the presence of acetic acid was found to be the best sorbent in this method for the extraction of apixaban with high extraction efficiency comparable to other types of UiO-66-NH metal organic frameworks.

Bimetallic metal-organic framework based dispersive solid phase extraction followed by using a carbon dot solution as the elution solvent; application in the extraction of imidacloprid and acetamiprid from pepper samples.

This study focuses on the dispersive solid phase extraction technique for the efficient extraction and enrichment of imidacloprid and acetamiprid from pepper samples. A synthesized sorbent was used for this purpose. Once the target analytes were adsorbed, the sorbent was separated using a centrifuge and the analytes were desorbed using a carbon dot solution.

An innovative technique for the extraction and stability of polyphenols using high voltage electrical discharge: HVED-Assisted Extraction of Polyphenols.

Polyphenols are the main group of phytochemicals with several biological activities. Due to the adverse effects of conventional solvent extraction methods, innovative extraction techniques have been used as alternatives to overcome these problems. High voltage electric discharge (HVED) is an eco-friendly innovative extraction technique based on the phenomenon of electrical breakdown in water.

Density tunable dispersive solid phase extraction of four organochlorine pesticides from edible oil sample using rhodamine B as a sorbent prior to GC-MS analysis.

In this study, a new method was used to evaluate the levels of four organochlorine pesticides in edible samples. In this method, a density tunable dispersive solid phase extraction procedure was coupled with gas chromatography-mass spectrometry. Rhodamine B was used as a sorbent, which was distributed throughout the oil matrix with the aid of evaporation of methanol.

Red beet betalains extraction process: A comprehensive review of methods, applications, and physicochemical properties.

Red beet extract is rich in bioactive compounds and possesses health-promoting properties. Moreover, the stability of red beet extract over a broad acidic pH range has given them great potential in developing new functional foods and drinks. The choice of extraction solvent and methodology significantly influences the efficiency of betalain extraction from plant vacuoles.

Synthesis of 1,2,4-triazole-based deep eutectic solvents modified nickel ferrite nanoparticles and their application in dispersive solid phase extraction of triazole pesticides prior to LC-MS/MS analysis.

A dispersive solid phase extraction method using new magnetic nanoparticles based on nickel ferrite was introduced for the extraction of six triazole pesticides (penconazole, hexaconazole, tebuconazole, diniconazole, triadimefon, and difenoconazole) from water samples before liquid chromatography-tandem mass spectrometry analyses. Initially, a new deep eutectic solvent was synthesized with 1,2,4-triazole and n-octanol for surface modification of the nanoparticles easily achieved through microwave radiation. The nanoparticles morphology, magnetic properties, adsorption capacity, isotherms, and crystalline patterns of the sorbent were examined.

Synthesis of MIP@COF@MIL-156@FeO composite and its application in dispersive solid phase extraction of montelukast in plasma and urine samples.

In this study, a new magnetic nanocomposite comprised of a molecularly imprinted polymer, metal organic framework, and covalent organic framework was synthesized and used in the dispersive solid-phase extraction of montelukast from plasma and urine samples. The extracted analyte was then analyzed using liquid chromatography-tandem mass spectrometry. The drug extraction process involved adding the synthesized nanocomposite to the biological sample.

Heteroatom cobalt-based metal-organic framework and reduced graphene oxide nanocomposite for dispersive solid phase extraction of caffeine from exhaled breath condensate samples of premature infants prior to HPLC-PDA.

A cobalt-based metal-organic framework and graphene oxide were combined to prepare a new nanocomposite for extracting of caffeine from exhaled breath condensate (EBC) samples. Dispersive micro solid phase extraction of caffeine was conducted using the nanocomposite as a sorbent by adding 10 mg of it to the sample solution and vortexing for 3 min. After extracting of the analyte, it was eluted using the mobile phase.

Application of magnetic AlFu MOF nanocomposite for the extraction and preconcentration of some pesticides from different distillates.

This research used a magnetic AlFu nano-metal-organic framework as an adsorbent for the first time. This approach extracts and preconcentrates eight pesticides from various distillates through a two-step process: magnetic dispersive micro solid phase extraction and dispersive liquid-liquid microextraction. Initially, the nanocomposite is dispersed into a sample solution containing the pesticides and NaSO.

Thin film microextraction of apixaban from plasma based on the covalent organic framework coated on a mesh prior to liquid chromatography-tandem mass spectrometry.

In this research, a new covalent organic framework was synthesized and utilized as a coating in thin film microextraction for the extraction of apixaban from plasma samples. This coating was applied to the mesh modified through immersion in a HF solution. The extracted drug was then analyzed using liquid chromatography-tandem mass spectrometry.

A fast and simple procedure for the synthesis of a zinc and 1,4-benzene dicarboxylic acid metal-organic framework and its evaluation as a sorbent for dispersive micro solid phase extraction of pesticide residues.

In this work, Zn-1,4-benzenedicarboxylate metal-organic framework was synthesized by a simple hydrothermal process and used in dispersive micro solid phase extraction of some pesticide from various fruit juice and water samples. Seven widely consumed pesticides in agriculture (chlorpyrifos, haloxyfop--methyl, oxadiazon, diniconazole, clodinafop-propargyl, fenpropathrin, and fenaxoprop--ethyl) were selected as target analytes. In this work, dispersive micro solid phase extraction was followed by a liquid phase microextraction method to achieve more enrichment of the analytes, and the enriched analytes were quantified using a gas chromatography-flame ionization detector.

Preparation of a new composite based on multilayer fullerene with mesoporous carbon nitride and its application in the extraction of tacrolimus and everolimus from plasma prior to LC-MS/MS analysis.

The development of new and efficient adsorbents for dispersive solid-phase extraction method, particularly prior to chromatography analysis, is increasing. In particular, this method is recommended for use before biological sample analysis. In this work, a new composite was prepared from mesoporous carbon nitrides and carbon nano-onions and was utilized for the extraction of tacrolimus and everolimus from plasma samples prior to high-performance liquid chromatography-tandem mass spectrometry analysis.

Triangular silver nanoprism-based chemosensor for recognition of hyaluronic acid in human biofluids: a new platform for monitoring osteoarthritis treatment using smartphone-assisted digital image analysis.

Hyaluronic acid (HA) possesses unique viscoelastic properties and low immunogenicity, making it suitable for various biomedical purposes such as viscosupplementation in osteoarthritis treatment, assistance in eye surgery, and wound regeneration. The need for its quantification in human biofluids is crucial in clinical studies. This research work presents a novel approach using paper-based and parafilm-based photochemical techniques, employing triangular silver nanoprisms (TA-AgNPrs) as optical nanoprobes for HA detection in human biofluids.

Identification of taurine biomarker in human biofluids using plasmonic patterns of silver nanostructure.

Taurine is now widely used as a new biomarker for cardiovascular and neurodegenerative diseases. This study discusses the importance of accurately determining taurine biomarker levels in various tissues and fluids for the early diagnosis of important pathologies and diseases. Current methods for taurine analysis face challenges such as low sensitivity, lack of selectivity, and complex procedures.

Acid-base reaction-based dispersive solid phase extraction of favipiravir using biotin from biological samples prior to capillary electrophoresis analysis.

In this study, an acid-base reaction-based dispersive solid-phase extraction method was developed for the extraction of favipiravir from deionized water, plasma and urine samples prior to its determination using a capillary electrophoresis-diode array detector. The target analyte was extracted from the samples using biotin as a green adsorbent. To reach this goal, the pH of the solution was first adjusted to 9.

Advancements in application of chitosan and cyclodextrins in biomedicine and pharmaceutics: recent progress and future trends.

The global community is faced with numerous health concerns such as cancer, cardiovascular and neurological diseases, diabetes, joint pain, osteoporosis, among others. With the advancement of research in the fields of materials chemistry and medicine, pharmaceutical technology and biomedical analysis have entered a new stage of development. The utilization of natural oligosaccharides and polysaccharides in pharmaceutical/biomedical studies has gained significant attention.

Development of dispersive solid phase extraction based on magnetic metal organic framework for the extraction of sunitinib in biological samples and its determination by high performance liquid chromatography-tandem mass spectrometry.

Herein, a simple, sensitive, and reliable dispersive solid phase extraction was reported for the efficient extraction of sunitinib from biological samples. To facilitate the extraction of the desired analyte from urine and plasma samples, magnetic MIL-101Cr (NH) @SiO @ NiFeO was synthesized by a hydrothermal method and applied as an effective sorbent during the extraction process. After adsorption of the drug using 10 mg of MIL-101Cr (NH) @ SiO @ NiFeO nanoparticles through vortexing (1 min), the sorbent was separatedfrom the sample solution using a magnet.

Development of a new continuous homogenous liquid phase microextraction procedure based on in-situ preparation of deep eutectic solvent; application in the analysis of aliphatic amines in urine samples by GC-MS.

In the present work, a new microextraction procedure combined with gas chromatography-mass spectrometry has been developed for the analysis of several aliphatic amines from urine sample. The sample preparation method was a continuous homogenous liquid phase microextraction that was based on in-situ preparation of 4-chlorophenol: choline chloride deep eutectic solvent. The deep eutectic solvent was prepared by passing the mixture of related compounds through a syringe barrel filled with exothermic salts (calcium chloride and potassium bromide).

Development of a hollow fiber-liquid phase microextraction method using tissue culture oil for the extraction of free metoprolol from plasma samples.

In this research, a method known as a hollow fiber-liquid-phase microextraction was employed to extract and concentrate free metoprolol from plasma samples. The extracted analyte was subsequently determined using high-performance liquid chromatography coupled with a diode-array detector. Several parameters, including hollow fiber length, sonication time, extraction temperature, and salt addition, were investigated and optimized to enhance extraction efficiency.

Optical dِِِِiscrimination of histamine and ethylenediamine in meat samples using a colorimetric affordable test strip (CATS): introducing a novel lab-on paper sensing strategy for low-cost ensuring food safety by rapid and accurate monitoring of biogenic amines.

Biogenic amines (BAs) are a group of organic compounds that are produced through the decarboxylation of amino acids by microorganisms. These compounds are commonly found in a variety of foods and are known to cause adverse health effects if consumed in high concentrations. Therefore, the development of sensitive and rapid detection methods for detection and determination of BAs is essential for ensuring food safety.

An innovative transportable immune device for the recognition of α-synuclein using KCC-1--CS modified silver nano-ink: integration of pen-on-paper technology with biosensing toward early-stage diagnosis of Parkinson's disease.

Parkinson's disease (PD), the second most frequent neurodegenerative illness, is a neurological ailment that produces unintentional or uncontrolled body movements, which should be diagnosed in its early stages to hinder the progression. Monitoring the concentration of α-synuclein (α-Syn) in body fluids can be one of the most efficient ways for PD early detection. In this work, a paper-based electrochemical immunosensor was designed for α-Syn bio-assay in human plasma samples based on encapsulation of the biotinylated antibody on novel dendritic fibrous nanosilica ((KCC-1--CS)-Ab).

Deep eutectic solvent-based pressurized liquid extraction combined with dispersive liquid-liquid microextraction of organophosphorus pesticide residues in egg powder prior to high-performance liquid chromatography analysis.

Herein, a deep eutectic solvent (DES)-based miniaturized pressurized liquid extraction in combination with DES-based dispersive liquid-liquid microextraction (DLLME) was developed for the extraction of organophosphorus pesticides (parathion-methyl, triazophos, parathion, diazinon, and phoxim) from egg powder samples prior to their analysis by a high-performance liquid chromatography-diode array detector. In this work, first, the analytes' extraction was done by a pressurized liquid phase extraction for effective extraction of the analytes from the solid matrix, and then they were concentrated on a DLLME for more concentration of the analytes to reach low limits of detections. The use of DESs was done in both steps to omit the use of toxic organic solvents.