Engineered Interleaved Random Glass Fiber Composites Using Additive Manufacturing: Effect of Mat Properties, Resin Chemistry, and Resin-Rich Layer Thickness.

Standard lay-up fabrication of fiber-reinforced composites (FRCs) suffer from poor out-of-plane properties and delamination resistance. While advanced manufacturing techniques (e.g.

Energy-Efficient Respiratory Anomaly Detection in Premature Newborn Infants.

Precise monitoring of respiratory rate in premature newborn infants is essential to initiating medical interventions as required. Wired technologies can be invasive and obtrusive to the patients. We propose a deep-learning-enabled wearable monitoring system for premature newborn infants, where respiratory cessation is predicted using signals that are collected wirelessly from a non-invasive wearable Bellypatch put on the infant's body.

RRM2B Is Frequently Amplified Across Multiple Tumor Types: Implications for DNA Repair, Cellular Survival, and Cancer Therapy.

plays a crucial role in DNA replication, repair and oxidative stress. While germline mutations have been implicated in mitochondrial disorders, its relevance to cancer has not been established. Here, using TCGA studies, we investigated alterations in cancer.

Forecasting Dose from Unobserved Times: Case Study of Transient Workers at a Nuclear Power Plant.

Objectives: To evaluate the likelihood of exceeding the occupational exposure limit (OEL) for annual ionizing radiation doses among transient workers at the Hope Creek Nuclear Generating Station, and to propose a method for forecasting exposures among transient workers in general.

Methods: We obtained personal dosimeter data from the Hope Creek Nuclear Generating Station for the period of January-December 2014, comprising 1955 monthly dose measurements from 498 transient workers. The majority of the transient workers (96%) did not report 12 months of data.

A neuronal network of mitochondrial dynamics regulates metastasis.

The role of mitochondria in cancer is controversial. Using a genome-wide shRNA screen, we now show that tumours reprogram a network of mitochondrial dynamics operative in neurons, including syntaphilin (SNPH), kinesin KIF5B and GTPase Miro1/2 to localize mitochondria to the cortical cytoskeleton and power the membrane machinery of cell movements. When expressed in tumours, SNPH inhibits the speed and distance travelled by individual mitochondria, suppresses organelle dynamics, and blocks chemotaxis and metastasis, in vivo.

Optimization of Non-Thermal Plasma Treatment in an In Vivo Model Organism.

Non-thermal plasma is increasingly being recognized for a wide range of medical and biological applications. However, the effect of non-thermal plasma on physiological functions is not well characterized in in vivo model systems. Here we use a genetically amenable, widely used model system, Drosophila melanogaster, to develop an in vivo system, and investigate the role of non-thermal plasma in blood cell differentiation.

Spatial-Temporal Analysis of Air Pollution, Climate Change, and Total Mortality in 120 Cities of China, 2012-2013.

China has had a rapid increase in its economy over the past three decades. However, the economic boom came at a certain cost of depleting air quality. In the study, we aimed to examine the burden of air pollution and its association with climatic factors and health outcomes using data from Chinese national and city-level air quality and public health surveillance systems.

Intracortical remodeling parameters are associated with measures of bone robustness.

Prior work identified a novel association between bone robustness and porosity, which may be part of a broader interaction whereby the skeletal system compensates for the natural variation in robustness (bone width relative to length) by modulating tissue-level mechanical properties to increase stiffness of slender bones and to reduce mass of robust bones. To further understand this association, we tested the hypothesis that the relationship between robustness and porosity is mediated through intracortical, BMU-based (basic multicellular unit) remodeling. We quantified cortical porosity, mineralization, and histomorphometry at two sites (38% and 66% of the length) in human cadaveric tibiae.

Bactericidal activity of chlorine-loaded carbide-derived carbon against Escherichia coli and Bacillus anthracis.

The authors investigated the bactericidal activity of high-chlorine-content nanoporous carbide-derived carbon (CDC) against the Gram-positive, spore-forming bacterium Bacillus anthracis and the common Gram-negative enteric bacterium Escherichia coli. Chlorine-loaded nanoporous CDC produced by thermochemical etching of metals and metalloids by chlorination of carbides can retain up to 40 wt % of chlorine. Etching temperature and the structure and composition of carbides allow tuning the porosity of CDC.