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Background: Previous studies on alterations in superficial fat compartments with age yielded contradictory results; the superficial fat tissue volume or thickness was reported to increase, decrease, or remain unchanged.

Aims: To investigate volumetric and dimensional changes in superficial midfacial fat tissue retrospectively in patients who underwent a repeated computed tomography (CT).

Methods: A total of 262 patients (mean age, 46 years; median elapsed time between two CT imagings, 56 months) were included.

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