335 results match your criteria: "Dr. Rajendra Prasad Government Medical College[Affiliation]"

Background: In recent years, there has been a growing utilization of minimally invasive (MI) techniques, which provide the potential advantages of minimizing surgical stress, post-operative pain, and hospitalization duration. Nevertheless, the existing body of literature primarily comprises of studies conducted at a single medical site, which are of low quality and lack a comprehensive analysis of treatment techniques exclusively focused on spondylolisthesis. We conducted this systematic review and meta-analysis to compare minimally invasive surgery (MIS) and open surgery (OS) spinal fusion outcomes for the treatment of spondylolisthesis.

View Article and Find Full Text PDF

Basal and stimulated inhibin B in pubertal disorders.

J Clin Endocrinol Metab

January 2025

3Department of Metabolism, Digestion and Reproduction, Imperial College London.

Pubertal disorders in the form of delayed puberty (DP) or precocious puberty (PP) can cause considerable anxiety to both children and parents. Since the clinical and biochemical signatures of self-limiting and permanent conditions overlap considerably, it can be hard to determine whether to offer them reassurance or intervention. Researchers have thus long been searching for a robust test to indicate that the process of endogenous puberty is underway and is likely to proceed to completion.

View Article and Find Full Text PDF

Objectives: Lymphangiosarcoma is a rare tumor that affects the upper limbs of patients who have undergone breast cancer surgery, including axillary dissection, followed by radiation therapy (RT) to the axilla and has a poor prognosis. F-FDG PET/CT may enable the earlier detection of malignant transformation in a setting of chronic lymphedema and help evaluate the extent and staging of the tumor, allowing earlier initiation of treatment options.

Case Presentation: We herein report a case of cutaneous lymphangiosarcoma in a 47-year-old breast carcinoma patient, which occurred 9 years after initial surgery and radiation therapy.

View Article and Find Full Text PDF
Article Synopsis
  • The study focuses on the effectiveness of F-FDG PET/CT in identifying distant metastasis and synchronous tumors in newly diagnosed head and neck cancer patients in North India.
  • A total of 281 patients were analyzed, revealing that 11.7% had distant metastases, primarily found in the lungs and bones, while 7% had synchronous malignancies, with lung cancer being the most common.
  • These results support the use of whole body F-FDG PET/CT for initial staging as it significantly impacts patient management by detecting additional malignancies early on.
View Article and Find Full Text PDF

Hip arthroscopy has emerged as the primary surgical intervention for Femoroacetabular Impingement Syndrome (FAIS), a common cause of hip pain in young adults, particularly athletes. This narrative review examines the long-term outcomes, complications, and debates surrounding arthroscopic management of FAIS. Key findings include sustained improvements in patient-reported outcomes, return to sport, and functional recovery, particularly in younger patients and those with cam-type FAIS.

View Article and Find Full Text PDF

Objective: To investigate whether induction/augmentation of labor in pregnant women with anemia increases the risk of postpartum hemorrhage (PPH) and whether this risk varied by indications for labor induction/augmentation and by anemia severity in pregnancy.

Methods: In a prospective cohort study of 9420 pregnant women from 13 hospitals across India, we measured hemoglobin concentrations at recruitment (≥28 weeks of gestation) and blood loss after childbirth during follow-up and collected clinical information about PPH. Clinical obstetric and childbirth information at both visits were extracted from medical records.

View Article and Find Full Text PDF

Understanding the health culture of tribal community is important as health problems among tribal communities and their care is influenced by sociocultural factors, which will help in the implementation of health services. The conventional way of improving the access for the general populations may not suit the tribal populations owing to their distinct culture and owing to health systems factors as well. A stepwise process was followed for the development of a protocol to study to strengthen the implementation of National Programme for Prevention and Control of Non-Communicable Diseases.

View Article and Find Full Text PDF

Aortic transection, a near-complete tear through the layers of the aorta, is a critical condition often resulting from trauma such as motor vehicle collisions. The urgency of managing aortic transection underscores the critical need for effective interventions. We report the case of a male in his early 50s with no significant medical history who presented to the emergency department following a motor vehicle collision, sustaining multiple injuries including a descending thoracic aortic transection.

View Article and Find Full Text PDF

Drugs used for pain management in gastrointestinal surgery and their implications.

World J Gastrointest Pharmacol Ther

September 2024

Department of Anaesthesia, Dr Rajendra Prasad Government Medical College, Tanda, Kangra 176001, Himachal Pradesh, India.

Pain is the predominant symptom troubling patients. Pain management is one of the most important aspects in the management of surgical patients leading to early recovery from surgical procedures or in patients with chronic diseases or malignancy. Various groups of drugs are used for dealing with this; however, they have their own implications in the form of adverse effects and dependence.

View Article and Find Full Text PDF

Formulation and pilot test of tuberculosis patient score card (TB-PSC) in selected public health care facilities of Himachal Pradesh, India.

Indian J Tuberc

July 2024

Department of Community Medicine, Dr. Rajendra Prasad Government Medical College, Kangra at Tanda, Himachal Pradesh, 176001, India. Electronic address:

Background: Community engagement is advocated to improve quality of services using community score card. Current study was done with the objective to formulate the TB-PSC and to carry out its feasibility assessment at three selected public healthcare facilities of Himachal Pradesh, India.

Methods: A mixed-method study design was adopted for the study and was carried out from April 2022 to March 2023.

View Article and Find Full Text PDF

Both myxedema crisis and Sheehan's syndrome are uncommon conditions. The first-time presentation as myxedema crisis is rare in Sheehan's syndrome. The present study describes the case of a 31-year-old female patient who presented with altered sensorium in the emergency room.

View Article and Find Full Text PDF
Article Synopsis
  • Anterior cervical discectomy and fusion (ACDF) is a common cervical surgery but comes with several complications, the implications of which this study aims to clarify.
  • The research focused on analyzing literature from 2012 to 2022 to evaluate the frequency and risk factors associated with complications such as dysphagia, pseudarthrosis, and adjacent segment disease (ASD).
  • Results indicated that dysphagia was the most common issue post-surgery, with factors like the use of bone morphogenetic protein influencing its occurrence, while other complications varied in their incidence with some, like esophageal perforations, being quite rare yet severe.
View Article and Find Full Text PDF

The aim of this systematic review and meta-analysis was to investigate the impact of early sodium-glucose cotransporter-2 (SGLT2) initiation on long-term cardiovascular outcomes and all-cause mortality among patients with acute coronary syndrome (ACS). For this study, we adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 guideline. Two researchers independently performed a comprehensive literature search on PubMed, Embase, and the Cochrane Library, spanning from the inception of each database to February 24, 2023, without language limitations.

View Article and Find Full Text PDF

Introduction: Gap non-union patellas are challenging to treat for an orthopedic surgeon. We hereby report a case of a 22-year-old person with a 3 cm gap nonunion, its surgical management, functional outcome, and implications for clinical practice.

Case Report: A 22-year-old active male presented to us with a background of comminuted fracture patella left side that he suffered 1 year ago, following which he was treated by open reduction and internal fixation (ORIF) with Tension Band Wiring (TBW).

View Article and Find Full Text PDF

Background: - (AB-PMJAY) as a financial risk protection scheme intends to reduce catastrophic health expenditure (CHE), especially among poor. The current study was carried out to assess the utility of AB-PMJAY in terms of reduction in CHE from before and after admission in a tertiary hospital in the northern state of India.

Methodology: It was a hospital-based cross-sectional study carried out from August 2020 to October 2021 at a public tertiary hospital of Himachal Pradesh, India.

View Article and Find Full Text PDF

Systemic Sclerosis in Males-Deciphering the Enigma of Erasmus Syndrome.

Indian J Dermatol

February 2024

Department of Dermatology, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India.

Background: Systemic sclerosis is an autoimmune connective tissue disease characterized by fibrosis in skin and internal organs. Chronic exposure to silica may not only lead to silicosis of lungs but also systemic sclerosis. Systemic sclerosis is relatively commoner in females; however, occupational exposure to silica in males makes them vulnerable to silica--associated systemic sclerosis (Erasmus syndrome).

View Article and Find Full Text PDF

Introduction: Citizen science (CS) is an emerging approach in public health to harness the collective intelligence of individuals to augment traditional scientific efforts. However, citizens' viewpoint, especially the hard-to-reach population, is lacking in current outbreak-related literature. We aim to understand the awareness, readiness and feasibility of outbreak-related CS, including digitally enabled CS, in low-income and middle-income countries.

View Article and Find Full Text PDF

Limb salvage surgery has revolutionized the approach to bone tumors in orthopedic oncology, steering away from historical amputations toward preserving limb function and enhancing patient quality of life. This transformative shift underscores the delicate balance between tumor eradication and optimal postoperative function. Primary and metastatic bone tumors present challenges in early detection, differentiation between benign and malignant tumors, preservation of function, and the risk of local recurrence.

View Article and Find Full Text PDF

Osteomyelitis, a significant global healthcare issue, often results from infections related to open fractures, surgery, or conditions like diabetic foot ulcers. This report describes a case of osteomyelitis in a 62-year-old female with various pre-existing health conditions. The patient initially presented with swelling, pain, and difficulty walking in the right lower extremity, accompanied by systemic symptoms.

View Article and Find Full Text PDF

Background: Tennis elbow (lateral epicondylitis elbow) is a self-limiting disease of indeterminate pathogenesis. Conservative therapy is the treatment of choice. In chronic tennis elbow with failure of conservative therapy; surgical treatment is a method of choice.

View Article and Find Full Text PDF
Article Synopsis
  • - The study examines the prevalence of type 2 diabetes among tribal populations in India, revealing a lower rate (4.77% based on RBG and 6.80% based on FBG) compared to the national average of 7.3% for the general population.
  • - Significant risk factors associated with higher diabetes prevalence include age, smokeless tobacco use, hypertension, and obesity.
  • - The research suggests that changes in dietary and lifestyle behaviors may lead to increased rates of hypertension and obesity in these communities, thereby raising diabetes prevalence, indicating a need for targeted healthcare interventions.
View Article and Find Full Text PDF

Objective: This study aimed to investigate the incidence of and risk factors for stillbirth in an Indian population.

Methods: We conducted a secondary data analysis of a hospital-based cohort from the Maternal and Perinatal Health Research collaboration, India (MaatHRI), including pregnant women who gave birth between October 2018-September 2023. Data from 9823 singleton pregnancies recruited from 13 hospitals across six Indian states were included.

View Article and Find Full Text PDF

Heart failure is a clinical condition in which the heart is unable to maintain adequate cardiac output. Liraglutide is a glucagon-like peptide 1 (GLP-1) analogue that is used for the treatment of type 2 diabetes mellitus, but recent evidence suggests that it might have a beneficial role in treating heart failure. We conducted a review of existing literature and found five relevant studies.

View Article and Find Full Text PDF