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Dr. M.G.R. Educational & Research Insti... Publications | LitMetric

230 results match your criteria: "Dr. M.G.R. Educational & Research Institute[Affiliation]"

Semiconductor metal oxide with TiO nanoparticles removes hazardous compounds from environmental samples. TiO nanoparticles have shown potential as an efficient photocatalyst by being employed as a nano-catalyst for the breakdown of organic contaminants in wastewater samples. To separate substances from contaminated samples, combined UV and visible light irradiation has been used.

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Background: Aberrant deoxyribonucleic acid (DNA) contributes to inflammasome orchestrated progression of chronic inflammatory diseases like diabetes and periodontitis. The purpose of the present study was to estimate salivary levels of DNA sensing inflammasomes, absent in melanoma 2 (AIM2), interferon γ inducible protein (IFI16), and cytokine interleukin 18 (IL18) in individuals with periodontitis, diabetes, and healthy controls and interpret its association with periodontal and diabetic parameters.

Methods: Salivary levels of AIM2, IFI16, and IL18 were estimated by enzyme linked immunosorbent assay (ELISA) in a total of 120 individuals (n = 30 in each group), namely, healthy (Group 1), periodontitis (Group 2), diabetes (Group 3), and diabetes with periodontitis (Group 4).

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Review Insights on Salivary Proteomics Biomarkers in Oral Cancer Detection and Diagnosis.

Molecules

July 2023

Department of Prosthodontics, Sree Balaji Dental College and Hospital, BIHER University, Pallikaranai, Chennai 600100, Tamil Nadu, India.

Early detection is crucial for the treatment and prognosis of oral cancer, a potentially lethal condition. Tumor markers are abnormal biological byproducts produced by malignant cells that may be found and analyzed in a variety of bodily fluids, including saliva. Early detection and appropriate treatment can increase cure rates to 80-90% and considerably improve quality of life by reducing the need for costly, incapacitating medicines.

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Triple-negative breast cancer (TNBC) is one of the destructive breast cancer subtypes which cannot be treated by current therapies, which is characterized by the lack of estrogen (ER), Progesterone (PR), and Human epidermal receptor (HER2). The treatment for this chemotherapy or radiotherapy and surgery are such treatments and also novel biomarkers or treatment targets can quickly require to improve the outcome of the disease. MicroRNAs are the most popular and offer prospects for TNBC diagnosis and therapy.

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Tuberculosis of the bones and joints is a relatively rare entity, even in endemic countries. The disease is an outcome of a infection. Tuberculosis of the small bones of the foot is extremely rare, requires a high index of suspicion for establishing the diagnosis, and is often associated with delayed diagnosis, ultimately affecting the treatment outcomes.

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Homeobox D10 (HOXD10) is a transcription factor from the homeobox gene family that controls cell differentiation and morphogenesis throughout development.Due to their functional interaction, changes in HOXD10 gene expression might induce tumors. This narrative review focuses on how and why the dysregulation in the signaling pathways linked with HOXD10 contributes to the metastatic development of cancer.

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HRFSVM: identification of fish disease using hybrid Random Forest and Support Vector Machine.

Environ Monit Assess

July 2023

Electrical and Electronics Engineering, Dr. M.G.R Educational and Research Institute, Chennai, Tamil Nadu, India.

Aquaculture fish diseases pose a serious threat to the security of food supplies. Fish species vary widely, and because they resemble one another so much, it is challenging to distinguish between them based solely on appearance. To stop the spread of disease, it is important to identify sick fish as soon as possible.

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Background: causes tuberculosis (TB), an infectious lung disease. There is mounting evidence linking low lipid levels to a variety of human diseases, including TB. Cholesterol, mainly due to its involvement in heart disease, gets more attention in recent years.

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Upper limb electromyographic analysis of manual wheelchair transfer techniques in individuals with spinal cord injury: A systematic review.

J Bodyw Mov Ther

July 2023

Department of Physiotherapy, Manipal College of Health Professions, Manipal Academy of Higher Education, Bangalore, India; KMCH College of Physiotherapy, Kovai Medical Center Research and Educational Trust, Coimbatore; The Tamil Nadu Dr M.G.R. Medical University, Chennai, India. Electronic address:

Background And Purpose: The objective of this study is to determine the upper limb muscle electromyographic (EMG) activity required during various manual wheelchair transfers in the population of spinal cord injury (SCI).

Methods: This review included observational studies reporting the (EMG) activity of upper limb muscles during wheelchair transfers in people with SCI. We searched electronic databases and reference lists of relevant literature between 1995 and March 2022 with English language limits, yielding 3870 total articles.

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In the current study, the co-precipitation technique was employed for the synthesis of Cadmium oxide (CdO) and Copper‒doped Cadmium oxide (Cu‒CdO) nanoparticles. The synthesized samples were subjected to powder X-Ray diffraction (P-XRD), Field emission scanning electron microscopy (FE-SEM), Energy-dispersive X-ray (EDX), Fourier transforms Infrared (FT-IR), UV-Vis spectroscopy, photoluminescence (PL), laser-induced fluorescence spectroscopy and antibacterial investigations. According to the P-XRD analysis, both the samples were simple cubic in structure and have average grain sizes of 54 and 28 nm, respectively.

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Background: Oxidative stress induced by free radical accumulation contributes to many pathologies, including cancer. Antioxidant defense system fails to scavenge free radicals when it is excessively accumulated. Assessing individual antioxidant enzymes and total antioxidant capacity could direct the customized therapeutic strategies.

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Oral cancer is a common and deadly kind of tissue invasion, has a high death rate, and may induce metastasis that mostly affects adults over the age of 40. Most in vitro traditional methods for studying cancer have included the use of monolayer cell cultures and several animal models. There is a worldwide effort underway to reduce the excessive use of laboratory animals since, although being physiologically adequate, animal models rarely succeed in exactly mimicking human models.

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Chronic musculoskeletal (MSK) pain is one of the most prevalent causes, which lead patients to a physician's office. The most common disorders affecting MSK structures are osteoarthritis, rheumatoid arthritis, back pain, and myofascial pain syndrome, which are all responsible for major pain and physical disability. Although there are many known management strategies currently in practice, phytotherapeutic compounds have recently begun to rise in the medical community, especially cannabidiol (CBD).

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Effect of task-based bilateral arm training on upper limb recovery after stroke: A systematic review and meta-analysis.

J Stroke Cerebrovasc Dis

July 2023

Department of Physiotherapy, Manipal College of Health Professions, Manipal Academy of Higher Education, Manipal, India; Centre for Comprehensive Stroke Rehabilitation and Research, Manipal Academy of Higher Education, Manipal, India. Electronic address:

Objective: Upper limb recovery is a crucial component of stroke rehabilitation aimed to maximize functional activities and reduce disability. Using both arms post stroke is essential to carry out many functional activities but the evidence on bilateral arm training (BAT) is understudied. To investigate the evidence for efficacy of task-based BAT on upper limb recovery, function, and participation post stroke.

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The Antioxidant Capacity of Breast Milk and Plasma of Women with or without Gestational Diabetes Mellitus.

Antioxidants (Basel)

March 2023

Department of Applied Human Nutrition, Faculty of Professional Studies, Mount Saint Vincent University, Halifax, NS B3M 2J6, Canada.

Women with gestational diabetes (GD) have reduced antioxidant capacity; however, the relationship between maternal diet, maternal biochemical capacity, breast milk concentration, and infant intake has not been adequately explored in the literature. An exploration of underlying mechanism(s) is warranted, particularly for nutrient antioxidants impacted by maternal intake. These nutrients may provide a means for modifying maternal and infant antioxidant capacity.

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Materials And Methods: stem bark was extracted with two different solvents, i.e., ethyl acetate and water, and preliminary phytochemical screening was performed.

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Background: The excess reactive oxygen species or free radicals reaction leads to oxidative injury to the biological components such as cells and tissues, which would result in the initiation and progression of carcinogenesis. The magnitude of oxidative damage depends primarily on the balance between free radicals (pro-oxidants) and antioxidant system activity.

Aim: To assess antioxidant status by evaluating the reduced glutathione (GSH) levels in various biological samples of patients with oral squamous cell carcinoma (OSCC) using available literature.

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Aim: The aim of the study is to compare the efficiency of Michigan (MI) varnish containing casein phosphopeptide (CPP) and amorphous calcium phosphate (ACP) and Fluoritop containing sodium fluoride (5% NaF) in the prevention and remineralization of white spot lesions (WSLs) around orthodontic brackets at days 28 and 56 after bonding.

Materials And Methods: A total of 30 patients were selected and divided into two groups I (MI varnish) II (Fluoritop varnish) of 15 patients in each group. All the patients were bonded and then varnish was applied around the brackets.

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Objective: Patients with moderate to severe preoperative pain have a high incidence of postoperative pain. The objective of this trial was to evaluate the efficiency of oral premedication with Aceclofenac (immediate release and controlled release) in the management of post-instrumentation pain in root canal treatment, in patients with moderate to severe preoperative pain.

Methods: Three-arm parallel, triple blinded randomized controlled trial was planned.

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This study aims to identify the role of subjective factors (age, sex, and comorbidities) and procedure-specific factors (aspiration volume) in influencing the yield of progenitor cells in bone marrow aspiration concentrate (BMAC) harvested from the iliac crest. A retrospective analysis was conducted on 58 patients (male:female = 31:27; mean age: 52.56 ± 18.

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Objectives: To estimate the concentration of nitrous oxide (NO) required for effective sedation to render dental treatment for an anxious child and to assess the child's behavior, patient acceptance, parental satisfaction, postoperative complications, and ease of manipulation of Porter Silhouette mask by the dentist during NO-O sedation.

Study Design: A total of 40 children, 6-10-year-old requiring dental treatment, were treated using NO sedation. The level of NO required for optimal sedation, patient behavior, level of acceptance of NO by the patient, clinical recovery score, and postoperative complications were observed throughout the study.

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Objective: This study was performed to assess smear layer formation and erosion after final irrigation protocols with metal and non-metal tips in the apical third of root canals.

Methods: Forty mandibular premolars were instrumented with ProTaper Gold files up to F3 and embedded in a closed silicone flask system. The teeth were subsequently cleaved and 4 sequential indentations (1 to 4 mm from the apical foramen) were prepared on the buccal root canal walls to standardize sites for environmental scanning electron microscopy (ESEM) imaging.

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Environmental contamination brought on by the discharge of wastewater from textile industries is a growing concern on a global scale. Textile industries produce a huge quantity of effluents containing a myriad of chemicals, mostly dyes. The discharge of such effluents into the aquatic environment results in pollution that adversely affects aquatic organisms.

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Nanosensors for the diagnosis and therapy of neurodegenerative disorders and inflammatory bowel disease.

Acta Histochem

February 2023

Department of electrical and electronics engineering, Dr. M.G.R Educational and Research Institute, Deemed to University, Chennai, India.

One of the areas of science which has immensely advanced in the recent years is nanotechnology. This area broadly revolves around matter at scales between 1 and 100 nm, where peculiar phenomena make way for cutting-edge applications. Today, nanotechnology has a daily impact on human life with numerous and varied possible advantages.

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To explore healthcare professionals' views about the training and support needed to rollout closed-loop technology to pregnant women with type 1 diabetes. We interviewed ( = 19) healthcare professionals who supported pregnant women using CamAPS FX closed-loop during the Automated insulin Delivery Amongst Pregnant women with Type 1 diabetes (AiDAPT) trial. Data were analyzed descriptively.

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