Effect of respiration and exercise on seismocardiographic signals.

Background: Seismocardiographic signals (SCG) are chest wall vibrations induced by mechanical cardiac activities. This study investigated the morphological changes in the SCG signal due to respiration and exercise.

Methods: Fifteen healthy subjects were recruited, and SCG was acquired before and after exercise.

International society of sports nutrition position stand: β-hydroxy-β-methylbutyrate (HMB).

Position Statement: The International Society of Sports Nutrition (ISSN) bases the following position stand on an analysis of the literature regarding the effects of β-Hydroxy-β-Methylbutyrate (HMB). The following 12 points have been approved by the Research Committee of the Society: 1. HMB is a metabolite of the amino acid leucine that is naturally produced in both humans and other animals.

A Rare Case of an Aggressive Mixed Germ Cell Tumor Following Testicular Torsion.

Testicular cancer is one of the leading malignancies affecting young men, with germ cell tumors (GCTs) being the most prevalent type. These tumors are classified into two main subtypes: seminomas and non-seminomatous germ cell tumors (NSGCTs), with the latter known for their higher likelihood of metastasis. Early detection through imaging and tumor markers like alpha-fetoprotein (AFP) and beta-human chorionic gonadotropin (HCG) is crucial for favorable outcomes.

A Case Report of Acute Pericarditis Presenting With Acute Aortic Dissection.

This case report presents a rare occurrence of acute pericarditis coinciding with acute aortic dissection (AAD), emphasizing the significance of recognizing and managing these dual conditions effectively. It highlights the necessity of a multidisciplinary approach and underscores the importance of maintaining a high index of suspicion regardless of symptomatology to ensure prompt patient management and complication prevention. This case describes a 91-year-old male patient, who initially presented with mild chest pain, and was later diagnosed with AAD alongside acute pericarditis.

The Overuse of Hepatobiliary Scintigraphy (HIDA) Scans: Are We Unnecessarily Using Nuclear Medicine Resources Instead of Proven Clinical Guidelines for Diagnosing Acute Cholecystitis?

Background Gallstone disease significantly burdens the United States healthcare system. While ultrasonography (US), physical exam, and laboratory findings are the recommended primary workup and diagnostic modalities, hepatobiliary scintigraphy (HIDA) scans are occasionally used as an adjunct for diagnosis. This study evaluates HIDA scan utilization in comparison to clinical and US findings based on the Tokyo guidelines for diagnosing acute cholecystitis.

Exploring the Therapeutic Potential of Glucagon-Like Peptide 1 (GLP-1) Receptor Agonists in Polycystic Ovary Syndrome.

Polycystic ovary syndrome (PCOS) is a complex endocrine disorder affecting women of reproductive age and is characterized by hormonal imbalances, insulin resistance, and reproductive dysfunctions. Glucagon-like peptide 1 (GLP-1) receptor agonists (GLP-1 RAs) are primarily used in diabetes management to enhance insulin release by stimulating GLP-1 receptors in the pancreas. The search strategy included randomized trials on the management of PCOS symptoms with GLP-1 RAs alone or in combination with other medications; meta-analyses, literature reviews, or case reports were excluded.

Procedural sedation performed by pediatric critical care physicians for children undergoing daily radiation therapy is effective and safe.

Radiation therapy targets tumor tissue and requires children to lay still, often necessitating sedation. Historically anesthesiologists provided procedural sedation, but pediatric critical care physicians now regularly administer sedation outside the operating room. Procedural sedation for radiation poses unique challenges.

Exploring Systemic Comorbidities and Lifestyle Factors Associated With Seborrheic Dermatitis: A Scoping Review.

Seborrheic dermatitis (SD), a chronic inflammatory skin condition consisting of itchy, red patches with greasy scales, has been linked to numerous systemic conditions. This review evaluates comorbidities and lifestyle factors that are associated with seborrheic dermatitis. A literary search was conducted in August 2024 using EMBASE, PubMed, and Medline Industries, and evaluated according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.

Pseudoangiomatous Stromal Hyperplasia: A Rare Case of Bilateral Axillary Ectopic Breast Tissue.

Pseudoangiomatous stromal hyperplasia (PASH) is a benign but rare mesenchymal proliferation of the mammary stroma, characterized by pseudovascular spaces within a hyperplastic matrix. PASH can be classified as either non-tumor-forming or tumor-forming. The non-tumor-forming type is an infiltrative and clinically undetectable mass, incidentally found in approximately a quarter of breast biopsies.

The Scarab Technique for Correction of Late-Presenting Sagittal Suture Craniosynostosis.

Introduction: Sagittal synostosis (SS) is the most prevalent form of craniosynostosis. It is the premature fusion of the sagittal suture, resulting in a "boat like" skull shape. Early surgical intervention is crucial to prevent complications, yet no standard procedure exists for patients over 12 months old.

Loop Ileostomy With Colonic Lavage: Case Report of an Alternative to Total Colectomy in the Setting of Fulminant Clostridium difficile Colitis.

Fulminant colitis is a severe and potentially life-threatening form of associated bacterial disease leading to inflammation and damage to the colon. Complications such as toxic megacolon, sepsis, and multi-organ failure commonly occur in individuals with compromised immune systems and recent antibiotic use. Management of colitis involves optimization of fluid and electrolyte balance, and elimination of bacteria commonly by administering vancomycin or fidaxomicin.

Cutaneous Squamous Cell Carcinoma Arising Within a Previously Irradiated Mycosis Fungoides Lesion.

Mycosis fungoides (MF), a form of cutaneous T-cell lymphoma (CTCL), increases the risk of other malignancies. A common and effective treatment for patients with MF is radiotherapy (RT), which itself also increases the risk of malignancies. One such malignancy that may result from both MF and RT is cutaneous squamous cell carcinoma (cSCC).

COVID-19 Infection and Acute Myeloid Leukemia: A Likely Marriage?

In the early era of COVID-19, characterization of long-term complications was unfeasible. But in early 2021, the authors came across a patient with a new diagnosis of Acute Myeloid Leukemia (AML) that was highly suspected as being secondary to a previous COVID-19 infection. The similarities of this anomaly to Hodgkin Lymphoma occurring after Epstein Barr Virus prompted the authors to perform a qualitative review of the literature for a possible pathway of how COVID-19 can cause AML.

Antibiotic Dispensing Practices Among Community Retail Pharmacies and Registered Drugstores: Results from a Simulated Client Study in Lilongwe, Malawi.

Introduction: Antimicrobial resistance (AMR) is largely driven by the inappropriate use of antibiotics. This has been attributed to the non-prescription sale of antibiotics in retail drug outlets. Despite the rising number of retail drug outlets in Malawi, the practice of drug dispensing in private pharmacies has not been evaluated.

Traumatic Thoracic Blast Injury With Extensive Soft Tissue Damage, Volumetric Muscle Loss, and Full-Thickness Burns From a Flashbang Detonation: A Case Report.

Chest trauma is a common injury in civilian and military polytrauma patients and is a leading cause of death and chronic disabilities. Evolving surgical techniques and advancements in chest wall reconstruction have improved clinical outcomes, reduced operative complications, and decreased mortality. In this case report, a 23-year-old male U.

A Review on the Effects of Aerobic Exercise on Immune Dysregulation in Polycystic Ovarian Syndrome.

Polycystic ovarian syndrome (PCOS) is the most common endocrine disorder of reproductive-aged females. However, much of its pathophysiology is not well investigated or understood. Research has demonstrated an association between PCOS and metabolic dysfunction, including insulin resistance.

Exploring the Therapeutic Potential of DPP4 Inhibitors in Alzheimer's Disease: Molecular Insight and Clinical Outcome.

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by amyloid-beta (Aβ) plaques, neurofibrillary tangles, and cognitive decline. Given the shared neuropathophysiological traits between AD and type 2 diabetes mellitus (T2DM), repurposing antidiabetic medications, such as dipeptidyl peptidase 4 inhibitors (DPP4i), has emerged as a promising therapeutic strategy. This review comprehensively evaluates the preclinical and clinical evidence supporting the potential of DPP4i in preventing or treating AD by modulating Aβ and tau pathology, improving cognitive function, reducing neuroinflammation and oxidative stress, and promoting neuronal survival.

Effectiveness of Digital Health Interventions (DHI) in Chronic Pain Management: A Scoping Review of Current Evidence and Emerging Trends.

This review aims to address the impact of digital health interventions (DHIs) on chronic pain management, specifically, mHealth, eHealth, wearable devices, virtual reality (VR), and artificial intelligence. The following study identifies and assesses DHIs' efficacy in specific chronic pain conditions and then extrapolates improved outcomes and patient groups that benefit from their use. Using a systematic methodology, this review synthesizes findings that could improve knowledge for patients and practitioners in chronic pain management while also addressing gaps in understanding the impact of DHIs.

The Association Between Overweight Obesity Status and Hypertension in a Rural Community in Dang District, Gujarat, India: A Cross-Sectional Study.

Background The relationship between overweight obesity status and hypertension is well-known throughout the world, especially in low socioeconomic communities and developing countries. Both high blood pressure and obesity are preventable risk factors for noncommunicable disease, death, and disability. The prevalence of obesity-overweight status in India is increasing faster than the global average, and diabetes in Southeast Asia has surged over the past few decades.