Exploring Anticancer Potential of Strains: Insights into Cytotoxicity and Apoptotic Mechanisms on HCT 115 Cancer Cells.

Introduction: This study aims to systematically assess the anticancer potential of distinct strains on Human Colorectal Tumor (HCT) 115 cancer cells, with a primary focus on the apoptotic mechanisms involved. strains were isolated from sheep milk and underwent a meticulous microbial isolation process. Previous research indicates that certain probiotic bacteria, including Lactobacillus species, may exhibit anticancer properties through mechanisms such as apoptosis induction.

Identifying Needs and Preparing for Curriculum Changes in Indian Dental Education.

Unlabelled: The aims of dental professional courses are to prepare dental healthcare providers to manage common dental diseases, perform surgeries, and offer prevention. They should also be equipped to understand the needs of the society they are serving and willing to amend their skills. As they are expected to be a part of a team providing health care, they should have the requisite leadership and managerial skills for leading the team to serve its objectives in the best possible way.

Mpox virus infection in women and outbreak sex disparities: A Systematic Review and Meta-analysis.

Background: Although the recent literature indicates that mpox (monkeypox) primarily affects men, there are also multiple reports in women. Estimates of the sex distribution of mpox patients and patterns will enable a better understanding of the ongoing mpox outbreak.

Methods: In this systematic review and meta-analysis, seven databases were searched for studies published in English up to January 4, 2023.

Assessment of the Impact of HPV Infection on the Incidence and Prognosis of Oral Cancers.

Objectives: The purpose of this research was to evaluate, in a tertiary care context, the effects of human papillomavirus (HPV) infection on the incidence and prognosis of oral malignancies.

Methods: At a tertiary care hospital, 100 patients who received an oral cancer diagnosis between 2020 and 2022 were the subject of a retrospective analysis. Medical records were used to gather clinicopathological data, and histopathological specimens' molecular analyses were used to ascertain the HPV infection status.

Whether Present Era Demand Change in Pharmaceutical Promotional Ways to be More Eco- and Doctor-Friendly? An Observational Study.

Aim: Pharmaceutical promotion is the principal aspect of the healthcare system. In this study, we aimed to portray the opinion of doctors and medical representatives (MRs) on conventional pharmaceutical ways (usage of promotional or educational paper materials and physician drug samples) for pharmaceutical promotion.

Materials And Methods: In this cross-sectional observational study, data were collected from doctors and MRs across India using self-administered Google forms.

Assessment of the Efficacy of Photobiomodulation (PBM) Therapy in Periodontal Treatment: A Longitudinal Study.

Objective: The intention of this longstanding study was to assess the effectiveness of photobiomodulation (PBM) therapy as a complementary periodontal therapy method.

Methods: Fifty patients with periodontal disease were recruited and randomly randomized to receive either PBM therapy (n = 50) or traditional periodontal management (n = 50) as the control group. Periodontal parameters were measured at baseline and 3 and 6 months after management, including gingival index, probing depth, and clinical attachment level.

Effectiveness of Different Bonding Agents in Minimally Invasive Cavity Preparations.

Objective: This research is meant to evaluate the effectiveness of different bonding agents in minimally invasive cavity preparations at a tertiary care center.

Materials And Methods: A prospective research was conducted involving patients requiring minimally invasive cavity preparations. Patients were randomly assigned to groups based on the bonding agent used.

Awareness of Orthodontists Toward Management of Orthodontic Patients Suffering with Diabetes Mellitus in Central India Population: A Cross-Sectional Survey.

Objectives: To evaluate orthodontists' awareness and knowledge about management of orthodontic patients with diabetes mellitus (DM) and determine if the treatment approach is according to the international guidelines.

Methods: This cross-sectional survey was conducted in Central India from January 2023to December 2023 and included 60 orthodontists from different dental clinics in private practice. Data were collected using a self-administered questionnaire, with questions about the orthodontic management of patients with DM.

Evaluating the Efficacy of Adjuvant Radiotherapy in the Management of Advanced Oral Cancer Cases.

Background: Because of its high rates of morbidity and death, especially in its late stages, oral cancer poses a serious threat to world health. Even with improvements in surgical and chemotherapeutic techniques, advanced oral cancer is still difficult to treat and frequently has unfavorable results.

Methods: Information on demographics, tumor features, treatment options, and results were gathered from medical records.

Trailblazer in Medicine: The Inspirational Journey of Dr. Anandibai Gopalrao Joshee.

Dr. Anandibai Joshee, emerging from a patriarchal society in Maharashtra, India, stands as a trailblazer in the annals of medical history, not only as the first Indian woman to earn a degree in Western medicine but also as a fervent advocate for women's rights. This paper delves into her life, exploring her contributions to the medical field, her advocacy for women's education, and the cultural impact she left on both India and the international community.

Effectiveness of a single dose of JYNNEOS vaccine in real world: A systematic review and meta-analysis.

Background: Mpox infection is a zoonotic illness that resembles smallpox. Vaccination is widely regarded as a vital effective method of preventing mpox, however, there is lack of consensus of effectiveness of a single dose of mpox vaccine in the current 2022-2023 outbreak. We pooled data from real-world studies to evaluate the efficacy of the JYNNEOS vaccination given as a single dosage.

Multi-organ clinical manifestations of Mpox: an umbrella review of systematic reviews.

Background: Mpox is a severe viral zoonosis that has emerged as a public health concern due to its potential for human-to-human transmission and severe illness. Understanding its clinical manifestations is crucial for effective management and control. Several systematic reviews have assessed various manifestations of Mpox.

Molar incisor hypomineralization (MIH): The "Why, What and How" of decision making for orthodontists.

Molar-incisor hypomineralization (MIH) presents a significant clinical challenge in orthodontics, with its complex etiology, variable presentation, and profound impact on enamel homeostasis. Utilizing Simon Sinek's "Golden Circle" method, this article systematically explores the implications of MIH within orthodontic practice. The "Why" emphasizes the critical need for orthodontists to understand MIH, given its prevalence and potential to disrupt treatment outcomes.