280 results match your criteria: "Dr. D. Y. Patil Vidyapeeth (Deemed to be University)[Affiliation]"

Potential of melatonin as a treatment option for long COVID: A call for research.

Br J Clin Pharmacol

December 2024

Department of Community Medicine, Dr. D. Y. Patil Medical College Hospital & Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed-to-be-University), Sant Tukaram Nagar, Pimpri, Pune, 411018, India.

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Introduction: Postoperative pain management after a cesarean section is essential to promote mother-infant bonding and ease of breastfeeding. Transdermal patches present a viable alternative to oral medications, offering controlled drug delivery and better bioavailability while avoiding first-pass metabolism, all of which can facilitate smoother recovery and rehabilitation.

Methods: This comparative, randomized, double-blind study was conducted on 70 parturients scheduled for cesarean section under spinal anesthesia, classified as ASA II.

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Renal cell carcinoma (RCC) of the clear cell type is the most common form of renal malignancy. Malignant pleural effusion (MPE) as the initial presentation of RCC is very rare. This case report presents a case of RCC that initially manifested as a pleural effusion, without the typical symptoms of flank pain, hematuria, or a palpable abdominal mass.

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Spinocerebellar Ataxia-6 Associated with Sleep Behavior Disorder.

J Assoc Physicians India

December 2024

Associate Professor, Department of Neurology, Dr D Y Patil Medical College, Hospital and Research Center, Dr D Y Patil Vidyapeeth (Deemed to be University), Pune, Maharashtra, India.

Spinocerebellar ataxia (SCA)-1, 2, 3, 6, and 31 are associated with sleep behavior disorder. We had a 66-year-old male who presented with late-onset cerebellar ataxia. Before 2 years, the onset of cerebellar symptoms, he had a history of sleep behavior disorder.

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Pseudoachalasia is a disorder in which symptoms, radiologic, endoscopic, and manometric results resemble idiopathic achalasia. Although these diagnoses may appear similar, their underlying causes and therapy differ significantly. Pseudoachalasia is frequently associated with malignancy, particularly primary adenocarcinoma of the esophagus or cardia.

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Comparative Evaluation of Videos with and without Binaural Beat Audio on Anxiety in Pediatric Patients during Dental Procedures: A Preliminary Study.

Int J Clin Pediatr Dent

September 2024

Department of Dental Research Cell, Dr. D. Y. Patil Dental College and Hospital, Dr. D. Y. Patil Vidyapeeth (Deemed to be University), Pune, Maharashtra, India; Biomedical, Dental and Morphological and Functional Imaging, University of Messina, Messina, Italy; Department of Medical-Surgical and Odontostomatological Specialties, University of Campania "Luigi Vanvitelli," Naples, Italy.

Article Synopsis
  • Pediatric patients often experience anxiety and behavioral challenges during dental care, prompting a need for effective behavior coaching techniques.
  • This pilot study investigates the effects of audiovisual stimuli, specifically binaural beats, on anxiety reduction in children aged 6 to 9 years during dental procedures.
  • Results show that children exposed to binaural beats experienced significantly greater reductions in pulse rate and increases in oxygen saturation compared to those without audio stimulation, highlighting its potential as a useful tool in pediatric dentistry.
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In India, vaccine hesitancy is one of the major hurdles to attaining widespread immunity against communicable diseases. Vaccines play a significant role, as was evident during the COVID-19 pandemic. However, factors such as misinformation, cultural beliefs together with distrust in healthcare providers are some of the barriers encountered during mass vaccination.

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This study investigated the clinical profile, etiology, and outcomes of eosinophilia in hospitalized patients. A total of 96 patients were included, with a mean eosinophil count of 3347.66 ± 1517.

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Background Hypoxic-ischemic encephalopathy (HIE) in neonates results from oxygen deprivation at birth, often leading to long-term neurological issues like cerebral palsy. Early detection is key to improving outcomes, but HIE remains a significant cause of neonatal complications. Here we aim to study the risk factors and predictors of outcome in moderate to severe HIE in inborn Term babies in the neonatal intensive care unit (NICU) Methods This prospective observational study was conducted in the NICU at a tertiary care center between August 2022 and July 2024.

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Alzheimer's Disease (AD), a neurodegenerative disorder characterized by cognitive decline, has traditionally relied on pharmacological interventions. However, the limitations of current treatments have spurred interest in neurosurgical approaches. This review explores the potential of neurosurgery, particularly deep brain stimulation (DBS), in modifying disease progression and enhancing cognitive function in AD patients.

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Non-pharmacological Methods of Deep Vein Thrombosis Prophylaxis in Orthopaedic Wards.

Cureus

November 2024

Department of Orthopaedics, Dr. D. Y. Patil Medical College, Hospital & Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed to be University), Pune, IND.

Deep vein thrombosis (DVT) is a dreaded post-operative complication for surgeons and warrants prophylactic measures. The risk of DVT is significantly higher in almost any and all major surgery. The common prophylactic measures are pharmacological methods like subcutaneous low-molecular-weight heparin and oral anticoagulants.

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Anterior cervical corpectomy and fusion (ACCF) is frequently the surgical management for myelopathy, radiculopathy, and cervical spine trauma. Although esophageal perforation is an uncommon complication, it remains a serious concern. This report details the case of a 50-year-old female who underwent a C6 corpectomy with C5-C7 ACCF due to degenerative pathology and subsequently developed an esophageal perforation that required revision surgery and surgical repair of the perforated esophagus.

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The gene encodes a nuclear pore complex protein (nucleoporin, 214 kilodaltons) which plays a critical role in messenger RNA export to the cytoplasm and import of substrates from the cytoplasm. Biallelic mutations in the gene have been associated with susceptibility to acute infection-induced encephalopathy type 9 (ILAE9) (Online Mendelian Inheritance in Man (OMIM), 114350), an autosomal recessive disorder. Herein, we describe for the first time, a fetus with hydrops and arthrogryposis multiplex with a homozygous novel consensus splice site variant in the NUP214 gene, chr9:g.

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Congenital anomalies are not regularly seen in day-to-day practice. Crossed fused renal anomalies are even rarer. A 50-year-old female patient presented with right-sided pain in the abdomen with intermittent episodes of burning micturition.

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Objective: To evaluate the functional and radiological outcomes of long bone fractures in non-union cases treated with nail and plate with osteo-periosteal flaps.

Methods: This prospective study included 20 patients with non-union long bone fractures treated at Dr. DY Patil Medical College, Pimpri, Pune over a two-year period.

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The pioneering German physician and microbiologist Heinrich Hermann Robert Koch (1843-1910) made pivotal contributions to the field of bacteriology, significantly advancing the germ theory of disease. His groundbreaking research in identifying the causative agents of anthrax, tuberculosis, and cholera revolutionized medical science and public health. Koch's development of essential microbiological techniques, such as using agar for bacterial cultures and introducing the Petri dish, transformed laboratory practices.

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Managing a patient with hypertrophic obstructive cardiomyopathy (HOCM) presents a significant challenge for any anesthesiologist. A deep understanding of the pathophysiology, alongside meticulous planning and hemodynamic monitoring, is essential. Key considerations include maintaining sinus rhythm, ensuring adequate preload and afterload, and preventing tachycardia.

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Article Synopsis
  • The study investigates the occurrence of acute kidney injury (AKI) in pediatric patients undergoing cardiac surgery, aiming to identify its incidence and possible risk factors while testing new early detection biomarkers.
  • Conducted from October 2022 to June 2024, the study involved 44 children and assessed kidney function before and after surgery using various measurements, including serum creatinine and novel biomarkers like cystatin C and NGAL.
  • AKI was found in 31.8% of patients, with a significant relationship between lower intraoperative hematocrit levels and higher AKI incidence, suggesting that maintaining optimal hematocrit and using low-dose vasopressin may help reduce AKI risk.
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Article Synopsis
  • - Cochlear nerve deficiency (CND) is a rare condition that can cause hearing loss in children and can significantly affect communication if not detected and addressed early.
  • - A case of a three-year-old boy with congenital hearing loss was presented, where MRI showed the right cochlear nerve was missing despite normal cochlear structure visible on a CT scan.
  • - The importance of using advanced imaging techniques like MRI for early diagnosis of CND was highlighted, along with recommendations for cochlear implantation and speech therapy to improve the child's hearing and communication skills.
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Article Synopsis
  • - The study investigates the relationship between vitamin D levels and neonatal sepsis by comparing serum vitamin D in 30 term neonates with sepsis to 30 healthy neonates.
  • - Results showed that neonates with sepsis had significantly lower vitamin D levels (16.0 ng/mL) than the control group (29.07 ng/mL), and certain clinical factors like mode of delivery and resuscitation needs differed between groups.
  • - The findings suggest a strong link between vitamin D deficiency and increased severity of sepsis, indicating that low vitamin D may contribute to worse outcomes in affected neonates.
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