1 results match your criteria: "Dr. Cipo Mangunkusumo General Hospital[Affiliation]"
Unveiling the interplay of YAP1-driven pathways and miR-340-5P expression: insights into nasopharyngeal cancer metastasis.
Eur Rev Med Pharmacol Sci
November 2024
Department of Anatomical Pathology, Faculty of Medicine, Universitas Indonesia, Dr. Cipo Mangunkusumo General Hospital, Jakarta, Indonesia.
Article Synopsis
- - This study examines the expression levels of Yes-associated protein (YAP1) and miR-340-5p in nasopharyngeal carcinoma (NPC) tissues, finding that both markers are significantly lower in metastatic cases compared to non-metastatic cases.
- - Analysis of NPC samples showed that YAP1 and miR-340-5p expression decreases with cancer progression, especially in advanced stages, and that these markers may be linked through the Hippo signaling pathway.
- - The findings suggest that YAP1 and miR-340-5p could function as tumor suppressors in NPC, highlighting their potential importance in cancer research and therapy development.