794 results match your criteria: "Dokuz Eyluel University Hospital[Affiliation]"
Hum Pathol
August 2024
Department of Pathology, Koç University Hospital, Istanbul, Turkey; Koç University Research Center for Translational Medicine (KUTTAM), Istanbul, Turkey. Electronic address:
A fusion between tubulin polymerization-promoting protein (TPPP), a regulatory cytoskeletal gene, and the chromatin remodeling factor, bromodomain-containing protein 9 (BRD9), TPPP-BRD9 fusion has been found in rare cancer cases, including lung and gallbladder cancers (GBC). In this study, we investigated the histopathological features of 16 GBCs previously shown by RNA sequencing to harbor the TPPP-BRD9 fusion. Findings in the fusion-positive GBCs were compared with 645 GBC cases from the authors' database.
View Article and Find Full Text PDFInt Urogynecol J
July 2024
Departement of Gynecology and Obstetrics, Bakırçay University School of Medicine, Gazi Mustafa Kemal, Kaynaklar Street, 35665, Menemen, İzmir, Turkey.
Wound Manag Prev
June 2024
Dokuz Eylül University Hospital, Inciralti, İzmir, Turkey.
Background: Living with an ostomy is a chronic condition, and self-care in such cases improves patient outcomes.
Purpose: To adapt and test the psychometric properties of the Turkish version of the Ostomy Self-Care Index (T-OSCI) and the Turkish version of the Caregiver Contribution to Self-Care in Ostomy Patient Index (T-CC-OSCI).
Methods: A psychometric study was conducted on a convenience sample of 202 adult patients with an ostomy and their 165 caregivers.
Front Endocrinol (Lausanne)
July 2024
Obesity and Lipodystrophy Center, Endocrinology Unit, University Hospital of Pisa, Pisa, Italy.
Acta Neuropathol Commun
June 2024
Department of Neurosurgery, School of Medicine, Acibadem University, 34752, Istanbul, Turkey.
MYC dysregulation is pivotal in the onset and progression of IDH-mutant gliomas, mostly driven by copy-number alterations, regulatory element alterations, or epigenetic changes. Our pilot analysis uncovered instances of relative MYC overexpression without alterations in the proximal MYC network (PMN), prompting a deeper investigation into potential novel oncogenic mechanisms. Analysing comprehensive genomics profiles of 236 "IDH-mutant 1p/19q non-co-deleted" lower-grade gliomas from The Cancer Genome Atlas, we identified somatic genomic alterations within the PMN.
View Article and Find Full Text PDFPharmacol Ther
August 2024
DNA Damage Laboratory, Physics Department, School of Applied Mathematical and Physical Sciences, National Technical University of Athens (NTUA), Zografou, 15780, Athens, Greece. Electronic address:
Mult Scler J Exp Transl Clin
May 2024
The Alfred Hospital, Melbourne, Australia.
Rev Assoc Med Bras (1992)
May 2024
Dokuz Eylül University, School of Medicine, Department of Obstetrics and Gynecology - İzmir, Turkey.
Objective: We aimed to assess the impact of the coronavirus disease 2019 pandemic on the clinical presentation of tubal ectopic pregnancies.
Methods: This retrospective cohort study was conducted at a tertiary center and included 76 cases of tubal ectopic pregnancies. The study period was divided into two groups: the pre-coronavirus disease group (January 2018 to February 2020, Group 1; n=47, 61.
Scand J Rheumatol
July 2024
Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics Rigshospitalet, Glostrup, Denmark.
Objective: To explore the registration of enthesitis among biologic-naïve patients with psoriatic arthritis (PsA) initiating tumour necrosis factor inhibitor (TNFi) treatment across 12 European registries, compare the disease burden and patient-reported outcomes (PROs) between patients with and without enthesitis, and assess the enthesitis treatment response.
Method: Demographics, clinical characteristics, and PROs at first TNFi (TNFi-1) initiation (baseline) were assessed in patients with PsA, diagnosed by a rheumatologist, with versus without assessment of entheses and between those with versus without enthesitis. Enthesitis scores and resolution frequency were identified at follow-up.
Medicine (Baltimore)
May 2024
Department of Radiology, Dokuz Eylül University Hospital, İzmir, Turkey.
This study aimed to assess the effect of the status of the tendon and patient factors on patient satisfaction after rotator cuff repair. Forty-six patients treated for tears with a minimum of 5-year follow-up were included. Gender, age, and active smoking status were recorded.
View Article and Find Full Text PDFEur J Heart Fail
June 2024
BHF Glasgow Cardiovascular Research Center, School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK.
Jpn J Radiol
September 2024
Medicine Faculty, Department of Radiology, Dokuz Eylül University, 15 Temmuz Sağlık Sanat Yerleşkesi/İnciraltı, İzmir, 35340, Turkey.
Purpose: To build a stroke territory classifier model in DWI by designing the problem as a multiclass segmentation task by defining each stroke territory as distinct segmentation targets and leveraging the guidance of voxel wise dense predictions.
Materials And Methods: Retrospective analysis of DWI images of 218 consecutive acute anterior or posterior ischemic stroke patients examined between January 2017 to April 2020 in a single center was carried out. Each stroke area was defined as distinct segmentation target with different class labels.
Medicina (Kaunas)
March 2024
Radiology Department, Faculty of Medicine, Dokuz Eylül University, 35220 İzmir, Turkey.
: Age estimation from skeletal remains and in living individuals is an important issue for human identification, and also plays a critical role in judicial proceedings for migrants. Forensic analysis of ossification centers is the main evaluation method for age estimation, and ossification degree can be determined using computed tomography analysis. The purpose of this study is to investigate the applicability of CT (computed tomography) in the analysis of left scapula ossification centers, for forensic age estimation in Turkish society.
View Article and Find Full Text PDFHandchir Mikrochir Plast Chir
April 2024
Division of Hand, Plastic and Aesthetic Surgery, LMU University Hospital, LMU Munich, München, Germany.
Adv Biol (Weinh)
May 2024
Izmir Biomedicine and Genome Center, Izmir, 35340, Türkiye.
Ophthalmic diseases affect many people, causing partial or total loss of vision and a reduced quality of life. The anterior segment of the eye accounts for nearly half of all visual impairment that can lead to blindness. Therefore, there is a growing demand for ocular research and regenerative medicine that specifically targets the anterior segment to improve vision quality.
View Article and Find Full Text PDFRadiat Oncol
April 2024
Department of Radiation Oncology, Emory University School of Medicine, Atlanta, GA, USA.
Objective: This study evaluates various craniospinal irradiation (CSI) techniques used in Turkish centers to understand their advantages, disadvantages and overall effectiveness, with a focus on enhancing dose distribution.
Methods: Anonymized CT scans of adult and pediatric patients, alongside target volumes and organ-at-risk (OAR) structures, were shared with 25 local radiotherapy centers. They were tasked to develop optimal treatment plans delivering 36 Gy in 20 fractions with 95% PTV coverage, while minimizing OAR exposure.
Ideggyogy Sz
March 2024
Dokuz Eylül University Hospital, Department of Neurology, Izmir, Turkey.
Background And Purpose:
Delirium is a common complication developing in elderly patients. Therefore, it is important to diagnose delirium earlier. Family caregivers play an active role in early diagnosis of delirium and build a bridge between health professionals and patients.
View Article and Find Full Text PDFJoint Bone Spine
July 2024
Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Denmark; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
Haematologica
August 2024
Miloš Mladenović, ;Charlotte Flasshove, Bojana Mišković, ;José-María Ribera-Santasusana, Martin Hoenigl, Juergen Prattes, Malgorzata Mikulska, Annarosa Cuccaro, Emel Bekirova, Josip Batinić, ;Nick De Jonge, Tatjana Adžić-Vukičević, ;Ľuboš Drgoňa, Hans Martin Orth, Florian Reizine, Monica Piedimonte, Jörg Schubert, Andrés Soto-Silva, Jorge Loureiro-Amigo, Laura Serrano, Lisset Lorenzo De La Peña, Anna Guidetti, Irati Ormazabal-Vélez, Sandra Malak, Maria Calbacho, Noemí Fernández, Rafael F. Duarte, Elizabeth De Kort, Guldane Cengiz Seval, Luisa Verga, Rui Bergantim, María-Josefa Jiménez-Lorenzo, Johan Maertens, Nina Khanna, Matthias Egger, Omar-Francisco Coronel-Ayala, Przemyslaw Zdziarski, Alessandro Busca, Elena Busch, Christian Bjørn Poulsen, François Danion, Tania Cushion, Sergio Pinzón, Yung Gonzaga, Austin Kulasekararaj, Hossein Zarrinfar, Baerbel Hoell-Neugebauer, Chi Shan Kho, Rémy Duléry, Martin Kolditz, Monica Fung, Alina Daniela Tanase.
EClinicalMedicine
May 2024
Hematology Unit, Fondazione Policlinico Universitario Agostino Gemelli - IRCCS, Rome, Italy.
Pediatr Crit Care Med
July 2024
Red Colaborativa Pediátrica de Latinoamérica (LARed Network), Montevideo, Uruguay.
Acta Orthop Traumatol Turc
January 2024
Department of Orthopaedics and Traumatology, Dokuz Eylül University Hospital, İzmir, Turkey.
Objective: We aimed to define minimal clinically important difference (MCID) values of patient-reported outcome measures (PROMs) for distal metaphyseal ulnar shortening and to assess the relationship between level of the osteotomy and time to bone union.
Methods: 20 patients who had distal metaphyseal ulnar shortening osteotomies due to ulnar impaction syndrome and had at least 6 months of follow-ups were included in this study. The mean follow-up period was 12.
J Geriatr Oncol
April 2024
Medipol University Hospital, Department of Radiation Oncology, İstanbul, Türkiye.
Introduction: The choice of treatment for rectal cancer often differs in older and younger patients, with the rate of radiotherapy use lower among older adults. In our daily practice, when evaluating a frail older patient with rectal cancer, we usually choose to give less treatment. This may be due to concern that the patient will not be able to tolerate radiotherapy.
View Article and Find Full Text PDFSemin Nephrol
January 2024
Division of Nephrology, Dokuz Eylül University Hospital, Balcova, Turkey.
Recent advances in the treatment of plasma cell disorders (PCDs) have provided a wealth of therapy alternatives and improved overall survival tremendously. Various types of PCDs are associated with kidney injury and end-stage kidney disease in a considerable number of patients. Kidney transplantation (KTx) is the best option for renal replacement therapy in select patients in terms of both quality of life parameters and overall survival.
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