4 results match your criteria: "Doheny Retina Institute of the Doheny Eye Institute[Affiliation]"
Purpose: To evaluate the safety and evidence of efficacy for oral 13-cis retinoic acid as a treatment for patients with subfoveal occult choroidal neovascularization (CNV) due to age-related macular degeneration (ARMD).
Methods: Patients with active, subfoveal occult CNV with no prior treatment of the subfoveal component were eligible for inclusion. Patients received 40 mg of 13-cis retinoic acid twice daily for 5 months, stopped treatment for 2 months, and then resumed treatment for 5 months.
Neuropilin-1 expression by endothelial cells and retinal pigment epithelial cells in choroidal neovascular membranes.
Am J Ophthalmol
December 2005
Doheny Retina Institute of the Doheny Eye Institute and Department of Ophthalmology, University of Southern California Keck School of Medicine, 1450 San Pablo Street, Los Angeles, CA 90033, USA.
Purpose: To determine if vascular endothelial growth factor (VEGF) coreceptor neuropilin-1 (NP-1) is expressed in choroidal neovascularization (CNV) and to localize the expression.
Design: Laboratory investigation.
Methods: Six CNV membranes (CNVMs) obtained from patients with subfoveal CNV attributable to age-related macular degeneration (AMD) underwent immunohistochemistry for VEGF receptor-2 (VEGFR-2) and NP-1.
Proposed mechanism for retinal tears after LASIK: an experimental model.
Ophthalmology
January 2004
Doheny Retina Institute of the Doheny Eye Institute, University of Southern California Keck School of Medicine, Los Angeles, California 90033, USA.
Objective: To demonstrate axial length changes associated with anterior shift of the lens/iris diaphragm and anterior vitreous base in human cadaver eyes during suction ring application preceding Moria LASIK, and to propose that these changes may be associated with anterior retinal tears.
Design: Human eye study.
Materials: Eight human eye bank eyes ranging in age from 65 to 73 years.
Use of radiation in the treatment of age-related macular degeneration.
Ophthalmol Clin North Am
December 2002
Doheny Retina Institute of the Doheny Eye Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
In this century, macular degeneration is likely to reach epidemic proportions. New treatment modalities are being evaluated for wet or neovascular age-related macular degeneration (AMD) and include radiation treatment. Radiation is known to potentially destroy vascular tissue, and low-dose radiation has been shown to inhibit new blood vessel growth.
View Article and Find Full Text PDF