1,035 results match your criteria: "Diyarbakır Gazi Yaşargil Research and Education Hospital; Diyarbakır-Turkey. drbernas@yahoo.com.tr.[Affiliation]"

Background: The imposter phenomenon is the unwillingness to acknowledge one's triumphs, which is common among doctors. Research on the imposter phenomenon among mental health professionals is limited, and the relationship between imposter phenomenon, burnout, and compassion fatigue has not been studied. The current study intended to test a hypothesized model of the specific impact paths among burnout, compassion fatigue, maladaptive perfectionism, and imposter phenomenon among mental health professionals.

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Analysis of ROMO1 Expression Levels and Its Oncogenic Role in Gastrointestinal Tract Cancers.

Curr Issues Mol Biol

December 2024

Department of Medical Biochemistry, Trabzon Kanuni Health Practice and Research Hospital, Trabzon Faculty of Medicine, University of Health Sciences, Trabzon 61250, Turkey.

Gastrointestinal tract cancers account for approximately one-third of cancer-related deaths. Early diagnosis and effective treatment are the most important ways to prevent cancer-related morbidity and mortality. ROMO1 has been shown to play an important role in many types of cancer.

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Background: In triple-negative breast cancer (TNBC) patients receiving adjuvant capecitabine, the impact of HER2 expression on survival outcomes is unclear.

Methods:  Between June 2017 and December 2023, 112 patients with TNBC who received adjuvant capecitabine due to residual masses after neoadjuvant chemotherapy (NACT) in three hospitals were identified. HER2 is analyzed through immunohistochemistry (IHC) and/or in situ hybridization in the core biopsy and/or post-surgical histopathologies.

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Background And Aim: Given the significance of pain management in the context of diabetic foot ulcer (DFU) care, particularly in terms of ensuring patient adherence to treatment regimens, this study was undertaken to ascertain the impact of cold washing on pain and comfort levels during diabetic foot care.

Methods: A single-blind randomized controlled trial was conducted in the chronic wound care clinic of a teaching and research hospital in the southeastern region of Turkey. The sample consisted of 68 patients, with 34 assigned to the cold application group and 34 assigned to the control group.

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Objective: Intracranial hemangiopericytomas (HPC) are rare tumors. Radiotherapy (RT) is frequently performed after surgery, depending on tumor size, location, and the type of resection. Moreover, RT is preferred as an effective treatment for local recurrence and metastasis.

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Objectives: As previous studies on the use of a cervical pessary to prevent preterm birth (PTB) have produced conflicting results, we aimed to investigate the feasibility, acceptability and safety of a new technique for inserting a cervical pessary and compare it with the traditional technique in patients at high risk of PTB.

Methods: Women at high risk of PTB treated with a cervical pessary between January 2018 and January 2021 were retrospectively evaluated. After applying exclusion criteria, a total of 68 eligible patients were identified and retrospectively analyzed.

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Purpose: To develop a nomogram to predict the probability of cesarean hysterectomy (CH) in placenta accreta spectrum disorders (PASD) patients.

Methods: Data from 520 patients who underwent surgery with a preliminary diagnosis of PASD at a tertiary center in southeast Turkey between 2013 and 2023 were collected, and 302 patients were included in the study. A predictive model based on clinical and ultrasonographic variables was developed using penalized maximum likelihood estimation (PMLE) regression analysis.

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Objective: The aim of the study was to determine the prevalence, risk, and predisposing factors of diabetic foot ulcers in adults with diabetes.

Methods: This study is multi-centered descriptive cross-sectional research. Data were collected between June 2022 and November 2022 in seven cities, including five teaching and research hospitals and two public hospitals.

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Objectives: Quality of life (QoL) is directly associated with physical-psychological well-being, family and environmental factors in patients with Mucopolysaccharidosis (MPS). The present study aims to investigate the factors affecting QoL in both MPS patients and their caregivers.

Methods: The sociodemographic characteristics, clinical findings, and special needs of 37 patients with MPS were questioned, among which 28 pediatric patients were evaluated for QoL using the KINDL-parents scale.

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Epilepsy is a chronic neurological disease characterized by recurrent seizures caused by abnormal electrical activity in the brain. The aim of our study was to investigate the effect of tDCS on oxidative stress, Ca, glutamate, GABA, AMPAR1, and NMDAR1 levels in kindling-induced epilepsy model. Behavioral tests evaluated motor and cognitive functions, while assessing oxidative stress, Ca, glutamate, GABA, AMPAR1, and NMDAR1 levels in hippocampal tissue.

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Article Synopsis
  • Chronic obstructive pulmonary disease (COPD) often leads to hospital readmissions, with a study involving 415 patients in Turkey revealing significant readmission rates of 42.4% within 30 days and 46% within 90 days after severe exacerbations.
  • Key risk factors for 30-day readmissions include high anxiety and depression scores, a history of severe exacerbations, hospital-acquired pneumonia, and frequent antibiotic use.
  • For 90-day readmissions, factors such as severe heart regurgitation, multiple moderate exacerbations, immunosuppression, and being hospitalized via the emergency department were significant contributors.
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  • COPD exacerbations can lead to increased morbidity and mortality, with prolonged hospital stays linked to various risk factors despite optimal care.
  • A study analyzed 434 COPD patients to identify factors influencing hospital length of stay (LOS), categorizing them into patient-related, disease-related, treatment-related, and hospital utility-related.
  • Key findings indicated that factors like biomass exposure, previous non-invasive mechanical ventilation, low bicarbonate levels, and increased oxygen needs were associated with difficult-to-manage exacerbations and longer hospitalizations.
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Acute pancreatitis (AP) is a clinical condition that arises acutely in the pancreas through various inflammatory pathways due to multiple causes. Turkish Society of Gastroenterology Pancreas Working Group developed comprehensive guidance statements regarding the management of AP that include its epidemiology, etiology, clinical presentation, diagnostic criteria, disease severity, treatment, prognosis, local and systemic complications. The statements were developed through literature review, deliberation, and consensus opinion.

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The Correlation Between Electrodiagnostic Severity and Patient-Reported Disability Among Carpal Tunnel Syndrome Patients.

Ann Indian Acad Neurol

November 2024

Department of Anesthesiology and Reanimation, Division of Pain Medicine, Gazi University, Ankara, Turkey.

Background And Objectives: The use, easy applicability, and costs of accurate diagnostic tools and their utility for early diagnosis, efficient treatment, and follow-up are important. In this study, we aimed to evaluate how electrophysiologic data were reflected in the clinical data of the patients with carpal tunnel syndrome (CTS).

Methods: This study included 102 patients with definitive CTS based on electroneuromyography.

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Heterozygous BTNL8 variants in individuals with multisystem inflammatory syndrome in children (MIS-C).

J Exp Med

December 2024

Section of Paediatric Infectious Disease, Department of Infectious Disease, Faculty of Medicine, Imperial College London, London, UK.

Multisystem inflammatory syndrome in children (MIS-C) is a rare condition following SARS-CoV-2 infection associated with intestinal manifestations. Genetic predisposition, including inborn errors of the OAS-RNAseL pathway, has been reported. We sequenced 154 MIS-C patients and utilized a novel statistical framework of gene burden analysis, "burdenMC," which identified an enrichment for rare predicted-deleterious variants in BTNL8 (OR = 4.

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Article Synopsis
  • The study investigates the effectiveness of bougie-guided cricothyrotomy versus traditional surgical cricothyrotomy in emergency airway management for obese patients using a 3D-printed manikin.
  • It involved 24 emergency residents who practiced both techniques, recording success rates, procedure times, and difficulty scores.
  • Results indicated that bougie-guided cricothyrotomy had a higher first-attempt success rate and was considered easier, especially for less experienced residents, though overall success rates and procedure times were similar for both methods.
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  • Cancer can lead to serious kidney issues in children requiring kidney replacement therapy (KRT), with a study identifying 287 pediatric KRT patients who had a history of cancer.
  • The study showed that those whose cancer caused KRT had a longer wait for kidney transplantation compared to matched controls, with a median time of 2.4 years for cancer patients versus shorter times for controls.
  • While childhood cancer survivors experienced increased mortality rates while on KRT (16% for group 1 and 23% for group 2) compared to controls, their long-term survival rates after kidney transplantation were similar to non-cancer patients.
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  • Migraine affects 15.2% of the global population, is a leading cause of disability, especially among women, and remains underdiagnosed and undertreated in many cases.
  • The condition displays both common and individual characteristics, with a varied presentation in symptoms, frequency, and response to treatments, influenced by genetic factors.
  • Education on migraine management is crucial for improving daily life for patients and reducing the number of individuals needing specialized care, allowing specialists to focus on more complex cases.
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Objective: This study aimed to assess the impact of Mulligan Reverse Natural Apophyseal Glides (RNAGS) applied to the upper thoracic region on pain, movement limitation, and function in individuals with mechanical neck pain.

Methods: Conducted between January 2021 and May 2021, the study involved 69 participants randomly assigned to a sham group, physiotherapy group, and Mulligan group. A two-week, 11-session treatment program was administered with shared physiotherapy interventions and stretching exercises to all groups.

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  • - The study focuses on improving the diagnosis of myocarditis using cardiac magnetic resonance imaging (CMRI) and investigates how common right ventricular (RV) involvement is in patients with acute myocarditis.
  • - Researchers analyzed CMRI data from 27 patients with acute myocarditis and compared it with a control group of 27 healthy individuals, finding significant differences in LV ejection fraction.
  • - Results indicated that while conventional RV assessment didn't show significant differences, CMRI-derived RV strain values were lower in the myocarditis group, suggesting potential subclinical RV dysfunction despite normal RV ejection fraction.
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  • The study analyzed global, regional, and national trends in injury burden and identified risk factors contributing to injuries using data from the GBD 2019.
  • In 2019, there were approximately 713.9 million injury incidents and 4.3 million injury-related deaths globally, with low bone mineral density emerging as the leading risk factor.
  • The findings emphasize the need for effective global injury prevention policies by highlighting the persistent impact of injuries on global health.
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Electroanatomic mapping guides complex atrial tachycardia ablations; however, challenges may emerge after pulmonary vein isolation. 3D mapping systems can reveal the mechanism of tachycardia and critical areas that need to be ablated. Sometimes, however, these areas may be located deep inside, to the extent that they cannot be successfully reached by endocardial ablation.

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Background: Nurses often administer intramuscular (IM) injections. However, they do not use the ventrogluteal (VG) site, although it is highly recommended.

Aim: This study investigated whether a mobile-assisted training and counseling program (intervention) encouraged nurses to use the VG site to administer IM injections.

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