3 results match your criteria: "Division of Urology Faculty of Medicine Tohoku Medical and Pharmaceutical University Sendai Japan.[Affiliation]"
Article Synopsis
- - A 78-year-old man with nausea and vomiting was found to have gastric outlet obstruction due to a tumor in the right renal pelvis and duodenal narrowing.
- - He underwent a gastrojejunostomy to alleviate symptoms and continue outpatient chemotherapy, but the treatment was ineffective and he passed away 9 months later.
- - Autopsy confirmed that the plasmacytoid urothelial carcinoma had invaded the duodenal wall, leading to the obstruction.
Introduction: The present study showed the involvement of immunosuppressive myeloid-derived suppressor cells during the disease progression in a 69-year-old man with a prostate cancer.
Case Presentation: The patient with metastatic PC (cT4N1M1ab) was initially treated with primary androgen deprivation therapy for 5 months and then chemotherapy with docetaxel, but he expired at the 8th month. In order to investigate whether myeloid-derived suppressor cells are implicated in the cancer exacerbation during androgen deprivation therapy, we assessed the long-term changes in peripheral blood myeloid-derived suppressor cell fractions by using flow cytometry.
Article Synopsis
- Plasmacytoid urothelial carcinoma is a rare and aggressive form of bladder cancer, presented in a 75-year-old woman who had retroperitoneal spread of the disease.
- After first-line chemotherapy with gemcitabine and cisplatin failed, a circulating tumor cell test identified a cell positive for programmed death-ligand 1, leading to second-line treatment with pembrolizumab.
- Ultimately, despite treatment, the cancer progressed with severe infiltration in the retroperitoneum, and the patient passed away, highlighting the aggressive nature of this cancer variant.