7 results match your criteria: "Division of Surgery and Interventional Science University College London London UK.[Affiliation]"
Vulval lichen sclerosus (VLS) is an inflammatory skin disease characterised by itching, apareunia, loss of vulval architecture and scarring. Heterogeneity in outcome reporting precludes comparison between treatments. This study aimed to systematically review outcome measures used to evaluate the efficacy of VLS treatments and present patients' treatment priorities.
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- International guidelines suggest that surgical removal of suspected localized renal cell carcinoma (RCC) is common, but some benign cases are identified post-surgery, highlighting a need for better non-invasive diagnostic tests.
- A systematic review was conducted on imaging tests' accuracy for T1 renal tumors, analyzing 27 studies involving over 2000 tumors, which highlighted various imaging modalities like CT, MRI, and PET scans.
- While [Tc]Tc-sestamibi SPECT/CT showed promising sensitivity and specificity, the optimal imaging strategy remains uncertain, calling for further research and standardization of diagnostic criteria across different imaging techniques.
Objective: The study aims to assess current international clinician attitudes, practices and barriers towards fertility assessment and preservation in patients undergoing radical inguinal orchidectomy (RIO) for testicular cancer.
Materials And Methods: An international online survey of urologists and urologists in training who perform RIO for testicular cancer was developed by the British Association of Urological Surgeons (BAUS) Sections of Andrology and Oncology and the British Urology Researchers in Surgical Training (BURST). The recruitment process used social media and the emailing lists of national urological societies.
Background: There is inconsistency in outcomes collected in renal cell cancer (RCC) intervention effectiveness studies and variability in their definitions. This makes critical summaries of the evidence base difficult and sub-optimally informative for clinical practice guidelines and decision-making by patients and healthcare professionals. A solution is to develop a core outcome set (COS), an agreed minimum set of outcomes to be reported in all trials in a clinical area.
View Article and Find Full Text PDFFeasibility of aspirin and/or vitamin D3 for men with prostate cancer on active surveillance with Prolaris® testing.
BJUI Compass
November 2022
Centre for Prevention, Detection and Diagnosis, Wolfson Institute of Population Health, Cancer Research UK Barts Centre Queen Mary University of London London UK.
Article Synopsis
- - The study aimed to test the feasibility of a randomized controlled trial (RCT) examining the effects of aspirin and vitamin D3 in patients with low-risk prostate cancer who are undergoing active surveillance and have undergone Prolaris® testing.
- - Out of 130 eligible patients, 104 (80%) participated, with 94 completing treatment; Prolaris® testing succeeded in 81% of diagnostic biopsies.
- - The findings revealed a 12-month disease progression rate of 43.3% among participants, with high treatment adherence (91%) in non-progressing patients, though there were two serious adverse events linked to aspirin.
Introduction: We evaluate the data of 12,644 Radical Cystectomies in England (Open, Robotic and Laparoscopic) with trends in the adaption of techniques and post-operative complications.
Methods: This analysis utilised national Hospital Episode Statistics (HES) from NHS England.
Results: There was a statistically significant increase ( < .
Background: Accurate prediction of mastectomy skin flap viability is vital as necrosis causes significant morbidity, potentially compromising results and delaying oncological management. Traditionally assessed by clinical judgement, a more objective evaluation can be provided using intraoperative imaging modalities. This systematic review aimed to compare all intraoperative techniques for assessment of mastectomy flap viability.
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