1 results match your criteria: "Division of Nephrology George Washington University School of Medicine[Affiliation]"
Article Synopsis
- SGLT2 inhibitors have been linked to reduced incidences of heart failure (HF) and related hospitalizations, but the exact mechanisms behind these benefits in invasive heart measurements are not well understood.
- A systematic review of randomized trials using PRISMA guidelines examined the impact of SGLT2i on heart function, measuring hemodynamics before and after treatment through right heart catheterization.
- The analysis of 3 studies involving 145 patients showed that SGLT2i significantly lowered pulmonary capillary wedge pressure at rest and during exercise, indicating potential improvements in heart function, although the effect on mean pulmonary artery pressure was not statistically significant.