8 results match your criteria: "Division of Cardiology and the Duke Clinical Research Institute[Affiliation]"
Cardiac Implantable Electronic Devices.
N Engl J Med
February 2024
From the Division of Cardiology and the Duke Clinical Research Institute, Duke University Medical Center, Durham, NC.
Outcomes According to Coronary Revascularization Modality in the ISCHEMIA Trial.
J Am Coll Cardiol
February 2024
Department of Cardiothoracic Surgery, Weill Cornell Medicine, New York, New York, USA. Electronic address:
Article Synopsis
- - In the ISCHEMIA trial, patients with stable coronary artery disease showed similar risk levels for ischemic events whether they underwent invasive treatments (like PCI or CABG) or conservative medical therapy.
- - The study specifically analyzed outcomes after revascularization, finding that CABG had a higher incidence of early primary outcome events compared to PCI, with 16.4% vs. 9.8% respectively, and many events occurring shortly after the procedures.
- - Overall, while early revascularization increased immediate risks of cardiovascular events, both CABG and PCI were linked to lower risks in the long term compared to conservative treatment, suggesting a complex risk-benefit scenario.
Optimism, Pessimism, and Pragmatism: Musings on the Cost of Medical Innovation.
JACC Heart Fail
February 2017
Division of Cardiology and the Duke Clinical Research Institute, Duke University, Durham, North Carolina. Electronic address:
Temporal trends in the use of early cardiac catheterization in patients with non-ST-segment elevation acute coronary syndromes (results from CRUSADE).
Am J Cardiol
November 2006
Division of Cardiology and the Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina USA.
We evaluated temporal trends in the use of early (<48 hours) catheterization in patients with non-ST-segment elevation acute coronary syndromes with respect to baseline risk features since publication of the American College of Cardiology/American Heart Association guidelines, which include a class IA recommendation for an early invasive strategy for high-risk patients with non-ST-segment elevation acute coronary syndromes. Overall, we found that early catheterization use increased from 53% to 61% during the 3 years after the guidelines were released, but the increased use of early catheterization was highest (11%) in the group that was at lowest risk of predicted mortality, and it was lowest (6%) in the group at highest risk of predicted mortality who would potentially receive the most benefit from an aggressive treatment approach. In conclusion, despite the overall increase in the use of early catheterization, the gap between the use of an early invasive strategy in the highest and lowest risk patients remains large and tends to increase over time.
View Article and Find Full Text PDFAcute clopidogrel use and outcomes in patients with non-ST-segment elevation acute coronary syndromes undergoing coronary artery bypass surgery.
J Am Coll Cardiol
July 2006
Division of Cardiology and the Duke Clinical Research Institute, Durham, North Carolina 27715, USA.
Objectives: We sought to characterize patterns of clopidogrel use before coronary artery bypass grafting (CABG) and examine the drug's impact on risks for postoperative transfusions among patients with non-ST-segment elevation acute coronary syndromes (NSTE ACS).
Background: Adherence in community practice to American College of Cardiology/American Heart Association guidelines for clopidogrel use among NSTE ACS patients has not been previously characterized.
Methods: We evaluated 2,858 NSTE ACS patients undergoing CABG at 264 hospitals participating in the CRUSADE (Can Rapid Risk Stratification of Unstable Angina Patients Suppress Adverse Outcomes With Early Implementation of the ACC/AHA Guidelines) Initiative.
N-acetylcysteine to prevent contrast nephropathy.
Am Heart J
March 2004
Division of Cardiology and the Duke Clinical Research Institute, Duke University Medical Center, Durham, NC, USA.
Which beta-blocker for heart failure?
Am Heart J
February 2004
Division of Cardiology and the Duke Clinical research Institute, Duke University Medical Center, Durham, NC 27715, USA.
Access site for cardiac catheterization.
Am Heart J
January 2004
Division of Cardiology and the Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27715, USA.