1 results match your criteria: "Dingli Clinical Medical College of Wenzhou Medical University[Affiliation]"
The variations in human orphan G protein-coupled receptor QRFPR affect PI3K-AKT-mTOR signaling.
J Clin Lab Anal
July 2021
Wenzhou Key Laboratory of Birth Defects, Wenzhou Central Hospital, Dingli Clinical Medical College of Wenzhou Medical University, Wenzhou, China.
Background: QRFPR is a recently identified member of the G protein-coupled receptor and is an orphan receptor for 26Rfa, which plays important role in the regulation of many physiological functions.
Methods: Here, we employed whole exome sequencing (WES) to examine the patients with intellectual disability (ID) and difficulty in feeding. We performed SIFT and PolyPhen2 predictions for the variants.