7 results match your criteria: "Dinanath Mangeshkar Hospital[Affiliation]"
Pathways of dye spread after injections in the paraspinal spaces-A cadaveric study.
Saudi J Anaesth
March 2024
Department of Anaesthesiology, Pain Medicine and Critical Care, AIIMS, New Delhi, India.
Article Synopsis
- The erector spinae plane (ESP) block has become popular but its diffusion toward the paravertebral area is unpredictable; researchers evaluated dye diffusion patterns in human cadavers to clarify this.
- In an experiment with six cadavers, different dyes were injected using an ultrasound technique at the thoracic vertebrae, with evaluations conducted to see how far the dye spread in surrounding areas.
- Results showed that dye from the ESP injection spread only to the dorsal area and not to the paravertebral space, while the inter-ligament space injection allowed for extensive dye spread both anteriorly and posteriorly, suggesting it could be a more effective approach.
Anatomic evaluation to compare the dye spread with ultrasound-guided pericapsular nerve group (PENG) injection with or without an additional suprainguinal fascia iliaca (SIFI) injection in soft embalmed cadavers.
J Anesth
August 2024
Department of Anaesthesiology, Pain Medicine and Critical Care, All India Institute of Medical Sciences (AIIMS), No. 6, 4th Floor, Porta Cabin, Teaching Block, New Delhi, 110029, India.
Background: Novel interfascial plane blocks like PEricapsular Nerve Group (PENG) and SupraInguinal Fascia Iliaca (SIFI) blocks are effective for management of hip fracture pain. We compared the difference in the distribution of the dye injected and nerves stained by the addition of the SIFI block to the PENG block.
Methods: A total of 24 designated dye injections were performed in eight soft-embalmed cadavers.
Management of human epidermal growth factor receptor 2-negative metastatic breast cancer: Role of poly adenosine diphosphate (ADP-ribose) polymerase inhibitors.
Indian J Cancer
March 2022
Department of Medical Oncology, TMC, Kolkata, West Bengal, India.
Article Synopsis
- The HER2-negative subset of metastatic breast cancers is diverse, including both hormone receptor-positive and hormone receptor-negative (triple-negative) cancers, each presenting unique treatment challenges.
- Endocrine therapy remains the primary treatment for HR-positive cases, but around 40% of patients develop resistance, complicating effective management.
- New treatments like CDK 4/6 inhibitors and poly (ADP-ribose) polymerase inhibitors (PARPi), especially for BRCA-mutated cases, are showing promise and ongoing trials aim to expand effective options for HER2-negative breast cancer.
Liquid biopsy: A potential and promising diagnostic tool for advanced stage non-small cell lung cancer patients.
Indian J Cancer
December 2017
Consultant Molecular Pathologist, Rajiv Gandhi Cancer Institute and Research Centre, Delhi, India.
More than 50% of non-small cell lung cancer (NSCLC) cases harbor an actionable mutation, and molecular testing at different intervals can help in personalized and targeted treatment. Core tissue biopsy and needle biopsy done at the time of diagnosis/disease progression are interventional, time-consuming and can affect the patients adversely. Noninterventional biomarker testing by liquid biopsy promises to revolutionize advanced stage cancer screening.
View Article and Find Full Text PDFA Rare Case Of Non Traumatic Myositis Ossificans Circumscripta.
J Orthop Case Rep
June 2016
Department of Spine, Dinanath Mangeshkar Hospital, Kothrud, Pune. India.
Introduction: Myositis ossificans circumscripta is a benign non neoplastic ossifying tumor presenting with bone like osteoid tissue extraskelletaly amidst the muscle planes. This condition when not associated with trauma is very trivial and considering the way it mimics certain characteristics, it may be misunderstood as a malignant neoplasm, abscess or antibioma. The aetiology of this atraumatic condition is still indistinct and remains a question unsolved.
View Article and Find Full Text PDFReply to the letter to editor.
Indian J Plast Surg
May 2015
Department of Plastic Surgery, Dinanath Mangeshkar Hospital, Pune, Maharashtra, India.
Bone scintiscanning in osteolytic lesions.
Clin Nucl Med
January 2004
SPECT-LAB, Nuclear Medicine Services, K 2/1 Erandawana Coop Society, Opposite Dinanath Mangeshkar Hospital, Pune.
Osteolytic lesions seen on plain radiographs can be caused by various disorders of the bones such as simple bone cyst, aneurysmal bone cyst, plasmacytoma, giant cell tumor, eosinophilic granuloma and tuberculosis. We studied prospectively Tc-99m-methylene diphosphonate bone scan findings in osteolytic lesions seen radiologically and followed them to histopathology. Interestingly, the scans in these patients helped to show if the lesions were monoostotic or polyostotic and, in some cases, ruled out malignant or infective etiology.
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