4,713 results match your criteria: "Dicle University; Diyarbakır-Turkey.[Affiliation]"

Objective: This subgroup analysis of the MORCOR-TURK (Mortality and Morbidity in Coronary Care Units in Türkiye) trial aimed to determine the short-term prognosis, mortality rates, and predictors for elderly patients followed in coronary care units (CCUs) in Türkiye.

Methods: The MORCOR-TURK trial is a national, non-interventional, multicenter observational study conducted in Türkiye (ClinicalTrials.gov number NCT05296694).

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to determine if patients who underwent percutaneous liver mass biopsy (PLMB) could be safely discharged after a two-hour monitoring period.
  • It involved 375 patients and found that minor complications occurred in 18.93% and major complications in 2.13%, mostly within the first two hours.
  • The conclusion indicated that the two-hour monitoring is sufficient for identifying most complications, suggesting that longer monitoring does not significantly enhance patient care.
View Article and Find Full Text PDF

Introduction: In this retrospective study, it was aimed to evaluate effects of Toll Like Receptor 4 (TLR4) and Toll Like Receptor 2 (TLR 2) gene polymorphisms on clinical outcomes in acute non-biliary pancreatitis patients.

Methods: A total of 108 acute non-biliary pancreatitis patients (ANBP) were retrospectively subjected to the study. Gender, age, number of attacks, hospitalization duration, amylase, lipase, aspartate aminotransferase (AST), alanine aminotransferase (ALT), leukocyte, C-reactive protein (CRP), total bilirubin, direct bilirubin, Atlanta score, ultrasonography (USG), Computer Tomography (CT) and patient outcome differences between TLR 4 Rs4986790, TLR 4 Rs4986791 and TLR 2 groups were evaluated.

View Article and Find Full Text PDF

Introduction: The therapeutic effect of different doses of the traditional aqueous extract of dried leaves of yerba mate ( A. St.-Hil.

View Article and Find Full Text PDF

Objective: Primary hypophysitis might be challenging to diagnose, and there is a lack of evidence regarding optimal treatment strategies due to rarity of the disease. We aim to investigate the clinical features and compare the outcomes of different management strategies of primary hypophysitis in a large group of patients recruited on a nationwide basis.

Design: A retrospective observational study.

View Article and Find Full Text PDF

Adverse effects of metamizole on heart, lung, liver, kidney, and stomach in rats.

BMC Pharmacol Toxicol

August 2024

Department of Internal Medicine Nursing, Faculty of Health Sciences, Erzincan Binali Yildirim University, Erzincan, 24100, Türkiye.

Background: Metamizole is banned in some countries because of its toxicity, although it is widely used in some European countries. In addition, there is limited information on its safety profile, and it is still debated whether it is toxic to the heart, lungs, liver, kidneys, and stomach.

Aims: Our study investigated the effects of metamizole on the heart, lung, liver, kidney, and stomach tissues of rats.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to evaluate the effects of converting laparoscopic surgery to open surgery during rectal cancer resection on both short-term and long-term outcomes.
  • Out of 84 patients, 21.4% required conversion to open surgery, resulting in increased intraoperative blood loss, but early clinical results were comparable between the two groups.
  • Long-term follow-up showed similar rates of recurrence and survival outcomes, suggesting that conversion to open surgery does not significantly harm patient prognosis.
View Article and Find Full Text PDF

The Effect of Breathing and Relaxation Exercises Training on Psychological Well-Being and Sleep Quality in Individuals Diagnosed With Schizophrenia: A Randomized Controlled Study.

Holist Nurs Pract

August 2024

Author Affiliations: Department of Psychiatic and Mental Health Nursing, Atatürk Health Science Faculty, Dicle University, Diyarbakir, Turkey (Dr Yildirim Üşenmez), and Department of Psychiatric Nursing, Inonu University, Malatya, Turkey (Dr Kavak Budak).

This study was conducted to determine the effect of breathing and relaxation exercises training on psychological well-being and sleep quality in individuals diagnosed with schizophrenia. This study was conducted at a community mental health center between October 2022 and April 2023 as a randomized controlled study with a pretest-posttest control group. The study's participants were 64 individuals diagnosed with schizophrenia (31 in the experimental group and 33 in the control group).

View Article and Find Full Text PDF

Objective: Placenta accreta spectrum (PAS) is defined as the attachment of the placenta to the uterine wall in varying degrees. However, the studies have explored that the underlying molecular mechanisms of the PAS are very limited. Sirtuins 1 (SIRT1) is associated with placental development by controlling trophoblast cell invasion and remodeling of spiral arteries.

View Article and Find Full Text PDF

"The association between HALP score and infection in acute ischemic stroke patients".

J Stroke Cerebrovasc Dis

November 2024

Department of Cardiology, Health Sciences University of Turkey, Diyarbakır Gazi Yasargil Education and Research Hospital, Diyarbakir, Turkey.

Background And Purpose: Stroke-associated infection (SAI) is related to increased mortality in acute ischemic stroke (AIS) cases. The HALP index is used to evaluate nutrition and inflammation. Our research aimed to assess the relation between HALP scores and infection risk in AIS cases.

View Article and Find Full Text PDF

This awareness study aimed to determine the ultrasound (US) examination rates in relation to US-confirmed metabolic dysfunction-associated fatty liver disease (MAFLD) diagnosis in internal medicine outpatients with type 2 diabetes (T2D) across Türkiye. A total of 6283 T2D patients were included in this multicenter retrospective cohort study conducted at 17 internal medicine clinics across Türkiye. The presence and indications for US performed within the last 3 years were recorded along with US-confirmed MAFLD rates, laboratory findings on the day of US, and referral rates.

View Article and Find Full Text PDF
Article Synopsis
  • - The study investigates how effective the McMahon score is in predicting mortality due to rhabdomyolysis following earthquakes, linking it to life-threatening conditions arising from trapped individuals.
  • - It reviewed data from 151 patients who went to the emergency department after an earthquake, analyzing factors like creatine kinase and serum creatinine, and found that the McMahon score is significant in differentiating patients at risk of mortality.
  • - With a score cutoff of 6, the McMahon score showed an area under the curve of 0.723, with 80% sensitivity and 64.5% specificity, highlighting its importance in emergency medicine for quick decision-making.
View Article and Find Full Text PDF

Introduction: Mutations in collagen type IV-associated genes lead to Ullrich congenital muscular dystrophy (UCMD) and Bethlem myopathy (BM). gene mutations have rarely been reported in patients with UCMD- and BM-like disorders not involving mutations. UCMD-2 results from homozygous mutations in the gene on the long arm of chromosome 6.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to evaluate the prevalence of pancreatic steatosis (PS) using transabdominal ultrasonography in Turkish gastroenterology clinics and identify associated factors.
  • A total of 1,700 volunteers revealed a PS prevalence of 68.9%, with factors like age, BMI, and metabolic syndrome linked to its severity.
  • The study also found that 11.8% of PS cases were in lean individuals, who were generally younger and had lower metabolic risk factors compared to those with non-lean PS.
View Article and Find Full Text PDF

Background:  Glutamatergic N-methyl-D-aspartate (NMDA) receptors play vital roles in memory formation. Changes in the activity of these receptors influence memory processes. Ketamine is a noncompetitive NMDA receptor antagonist drug with promising mood-altering and pain-reducing effects in low doses.

View Article and Find Full Text PDF

Effects of Boric Acid on Laminated Composites: An Experimental Study.

Polymers (Basel)

July 2024

Institute of Science, Dicle University, Diyarbakır 21280, Turkey.

In this study, the effect of boric acid (HBO) on fiber-reinforced layered composites was investigated. Glass fiber-reinforced epoxy composites were used, and the effects of boric acid on thermal and mechanical properties were investigated. For this purpose, composite plates were manufactured by adding boric acid (BA) to the epoxy in different ratios (0, 0.

View Article and Find Full Text PDF

Introduction: Hereditary spastic paraplegia () is a genetically and clinically heterogeneous group of rare neurodegenerative disorders. SPG45 is the AR inherited type of complicated SPG, which is due to a mutation in the gene.

Case Presentation: Two sisters, aged 8 and 4, exhibited delayed motor development since early childhood.

View Article and Find Full Text PDF
Article Synopsis
  • The study evaluated the effectiveness and safety of using granulocyte-colony stimulating factor (G-CSF) as a preventive treatment during chemoimmunotherapy for extensive-stage small cell lung cancer (ES-SCLC).
  • A total of 119 patients were analyzed, comparing those who received G-CSF to those who did not, with results indicating better response and disease control rates in the G-CSF group, although the differences were not statistically significant.
  • Overall, using G-CSF alongside the treatment protocol did not significantly improve efficacy or increase side effects, suggesting it can be safely integrated into treatment for ES-SCLC patients.
View Article and Find Full Text PDF

Objective: To evaluate the efficiency of pemetrexed cisplatin in comparison with gemcitabine cisplatin and to validate the EORTC (European Organisation for Research and Treatment of Cancer) prognostic score in combination chemotherapy treatment for malignant pleural mesothelioma.

Study Design:  An observational study. Place and Duration of the Study: Department of Oncology, Dicle University Hospital, Diyarbakir, Turkiye, from October 2000 to November 2017.

View Article and Find Full Text PDF

Purpose: To evaluate the neuroprotective effect of resveratrol, urapidil, and a combined administration of these drugs against middle cerebral artery occlusion (MCAO) induced ischemia/reperfusion (IR) injury model in rats.

Methods: Thirty-five rats were divided into five groups of seven animals each. Animals in IR, IR resveratrol (IRr), IR urapidil (IRu), and IR + combination of resveratrol and urapidil (IRc) were exposed to MCAO induced cerebral ischemia reperfusion injury model.

View Article and Find Full Text PDF

Background: Blood culture-negative endocarditis (BCNE) is a diagnostic challenge, therefore our objective was to pinpoint high-risk cohorts for BCNE.

Methods: The study included adult patients with definite endocarditis. Data were collected via the Infectious Diseases International Research Initiative (ID-IRI).

View Article and Find Full Text PDF
Article Synopsis
  • This study investigates out-of-hospital cardiac arrest (OHCA) data in Türkiye, focusing on prognostic outcomes and influencing factors for patients aged 18 and older who were treated at 28 medical centers.
  • It found a survival rate upon hospital discharge of only 4.4%, with a significant majority of patients not receiving bystander CPR, which was only performed in 2.9% of cases.
  • Key predictors for better outcomes included male gender, initial shockable heart rhythms, shorter prehospital CPR duration, and no need for CPR in the emergency department, highlighting the importance of timely and effective CPR in emergencies.
View Article and Find Full Text PDF

Comprehensive phytochemical analysis of Salvia hispanica L. callus extracts using LC-MS/MS.

Biomed Chromatogr

October 2024

Department of Plant Breeding and Genetics, Faculty of Agriculture and Environment, The Islamia University of Bahawalpur, Bahawalpur, Pakistan.

In this research, the study utilized the root, leaf, and petiole parts of in vitro grown Salvia hispanica plants as explants. Following UV-C treatment applied to developing callus, methanol extracts were obtained and analyzed using liquid chromatography-mass spectrometry (LC/MS) to investigate their anticancer properties. First, the seeds of S.

View Article and Find Full Text PDF

Objective: Cervical cancer has a very important place in female infertility and ranks fourth among cancers affecting women. Curcumin (CUR) is closely associated with the expression and activity of various regulatory proteins. It is also known that curcumin has preventive and therapeutic effects on various types of cancer.

View Article and Find Full Text PDF

Author Correction: Momordica charantia reduced ovarian ischemia - reperfusion injury by suppressing APAF-1 expression.

Eur Rev Med Pharmacol Sci

July 2024

Department of Histology and Embryology, Medical Faculty, Dicle University, Diyarbakır, Turkey.

Eur Rev Med Pharmacol Sci 2023; 27 (6): 2182-2188-DOI: 10.26355/eurrev_202303_31751-PMID: 37013735, published on March 30, 2023. After publication, the authors have contacted the journal to correct and update information contained in the Acknowledgments section.

View Article and Find Full Text PDF