4,731 results match your criteria: "Dicle University; Diyarbakır-Turkey.[Affiliation]"

Background/objectives: Attention-Deficit/Hyperactivity Disorder (ADHD) is associated with an increased risk of obesity and disordered eating behaviors. This study compared weight status and eating behaviors among drug-naïve ADHD children, those on stimulant monotherapy, those on combined stimulant and antipsychotic treatment, and healthy controls.

Methods: This cross-sectional study included 547 children aged 6-12 years from four Turkish provinces: 361 with ADHD (152 drug-naïve, 156 on stimulants, and 53 on combined therapy), and 186 healthy controls.

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Background: The integration of robotic technology into surgical procedures has gained considerable attention for its promise to enhance a variety of clinical outcomes. Robotic deep inferior epigastric perforator (DIEP) flap harvest has emerged as a novel approach for autologous breast reconstruction. This systematic review aims to provide a comprehensive overview of the current techniques, outcomes, and complications of robotic DIEP flap surgery.

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The fear of COVID-19, health literacy and levels of compliance with prevention measures of adult individuals in Turkey.

J Infect Dev Ctries

September 2024

Department of Nursing, Atatürk Faculty of Health Sciences, Dicle University, Sur/Diyarbakır, Turkey.

Introduction: It is known that health literacy and fear of COVID-19 are effective in complying with COVID-19 prevention measures. A limited number of studies have shown the relationship between health literacy, fear of COVID-19, and compliance with COVID-19 prevention measures. The purpose of this study is to investigate the fear of COVID-19, health literacy, compliance levels with prevention measures of adult individuals and influential factors.

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Pectinases are commonly industrially synthesized by molds. This study aimed to optimize pectin lyase synthesis by a bacterium, Pseudomonas fluorescens, using both the one-factor-at-a-time (OFAT) method and response surface methodology. First, on optimization of pectin lyase fermentation by the OFAT method, the effects of pectin, peptone, yeast extract, (NH)SO, pH, and salts were investigated.

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Chronotype is the temporal behavior of an organism. Social jetlag, fear of missing out (FoMO), and phubbing have received increasing attention recently and are closely related to sleep quality. This study aimed to explore the relationship between chronotype and these factors and their effects on sleep quality among medical students.

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Phytochemical composition, antimicrobial, antioxidant, and wound healing activities of .

Z Naturforsch C J Biosci

October 2024

Department of Food Hygiene and Technology, Faculty of Veterinary Medicine, Afyon Kocatepe University, 03200, Afyonkarahisar, Türkiye.

The antioxidant, antimicrobial, anticarcinogenic, wound healing activities and phenolic substance profile of aqueous extracts prepared using branch, leaf, flower parts and above-ground parts of were determined in the study. The analyses indicate that the total phenolic substance contents and total antioxidant status are higher in the mix, flower, and leaf extracts. The extracts reduced cell viability in HGF cells more than in A549 cells.

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Effect of dietary carbohydrate quality index on the severity of premenstrual symptoms.

Health Care Women Int

October 2024

Nutrition and Dietetic Department, Ataturk Faculty of Health Sciences, Dicle University, Diyarbakır, Turkey.

The objective of the researchers of this study is to evaluate the effect of the Carbohydrate Quality Index (CQI) in the diet of university students living in dormitories on the severity of premenstrual symptoms. The researchers applied a survey to the students, including questions about their sociodemographic characteristics and eating habits, Food Frequency Questionnaire (FFQ), and Premenstrual Symptom Scale (PMSS). A total of 606 female students were included as participants in the study.

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Supra-Aortic Branch Occlusion From Takayasu Arteritis.

Echocardiography

October 2024

Cardiology Department, Dicle University Hospital, Diyarbakır, Turkey.

This illustration depicts the complete occlusion of all supra-aortic branches due to Takayasu arteritis, as shown in invasive coronary angiography and CT angiography (a) Catheter angiography showing the occluded branches of the aortic arch (*). (b) Sagittal CT angiography showing calcification in the occluded supra-aortic branches (arrows) and thickened aortic wall (dashed arrow).

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Objectives: Current guidelines suggest that patients with cystic fibrosis (CF), who are over the age of 10, should be annually evaluated with oral glucose tolerance test (OGTT). In this study, it was aimed to evaluate the OGTT results in patients above the age of 10, who were followed up in our center with the diagnosis of CF.

Methods: In the study, 46 patients with CF at the age of 10 and above, who underwent OGTT were included.

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Blood transfusion in pediatric intracranial tumor surgery.

BMC Anesthesiol

October 2024

Department of anesthesiology and reanimation, Faculty of Medicine, Dicle University, Diyarbakır, Turkey.

Article Synopsis
  • Pediatric central nervous system tumors are the most common solid tumors in children and can lead to serious health issues; the study investigates factors affecting the need for blood transfusions during surgeries for these tumors.
  • A retrospective analysis of 138 patients under 15 years old who had craniotomy from January 2018 to December 2023 found that 44.9% required intraoperative blood transfusions, with key factors identified as age under 4 years and surgery lasting over 490 minutes.
  • The research concludes that younger age and longer surgical duration are significant risk factors for requiring blood transfusions, highlighting the importance of careful monitoring in these cases to prevent complications.
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  • * Researchers analyzed aerial parts of the plant from Adana, Türkiye, using an ethanol extract that revealed 39 different chemical constituents, with hyperoside, p-coumaric acid, and rutin being key components.
  • * The extract exhibited strong antioxidant activity and showed significant cholinesterase inhibition, indicating potential health benefits, while also proving effective against a specific bacterial strain, Enterococcus faecalis.
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  • The ARTEMIS registry investigates Peripartum Cardiomyopathy (PPCM), a serious condition occurring during late pregnancy or shortly after childbirth, focusing on clinical characteristics and outcomes in Turkish patients.
  • The study observed 293 women primarily aged 25-35 diagnosed with PPCM, mostly presenting symptoms like shortness of breath, and found a low usage of advanced imaging techniques, relying mainly on echocardiography.
  • Results indicated a 5.1% mortality rate among patients, emphasizing the need for better education for healthcare practitioners and the critical role of national registries in managing rare diseases like PPCM.
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Common viral respiratory infections in children with cancer during the COVID-19 pandemic: a multicenter study from Türkiye.

Turk J Pediatr

October 2024

Department of Pediatric Hematology Oncology, Yıldırım Beyazıt University Faculty of Medicine, Ankara Bilkent City Hospital, Ankara, Türkiye.

Article Synopsis
  • During the COVID-19 pandemic lockdown, the study assessed respiratory viral infections in children with cancer, highlighting their clinical impact.
  • Of the 265 episodes evaluated, human rhinovirus/enterovirus was the most common pathogen identified, with significant complications noted, including a higher rate of lower respiratory tract infections.
  • The findings emphasize the necessity for quicker detection and treatment of respiratory viruses to prevent severe outcomes in this vulnerable population.
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  • The study investigates how diet quality and modifiable risk factors, like nutritional status and inflammation, relate to depression and anxiety in patients undergoing hemodialysis (HD) for end-stage renal disease.
  • It involved assessing 216 patients using dietary records, psychological scales, and various health measurements to analyze the connections between these factors.
  • Findings revealed a high prevalence of depression (59.2%) and anxiety (35.1%) among participants, with specific nutritional markers identified as significant predictors for both psychological issues, suggesting the importance of addressing diet in mental health for HD patients.
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  • The study examines the role of Her2 status in early stage triple negative breast cancer (TNBC) patients undergoing neoadjuvant chemotherapy, revealing conflicting results regarding its prognostic impact.
  • A total of 620 female TNBC patients were analyzed, with 68.9% having Her2-0 and 31.1% having Her2-low status; the rates of pathological complete response (pCR) were similar between these groups.
  • While the Her2-0 group showed better disease-free survival (DFS), the overall survival (OS) rates were similar between the two groups, indicating the need for further research into the implications of Her2 status in this treatment context.
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The effect of hydrophilic statins on adiponectin, leptin, visfatin, and vaspin levels in streptozocin-induced diabetic rats.

Naunyn Schmiedebergs Arch Pharmacol

October 2024

Equine and Training Program, Plant and Animal Production Department, Vocational School of Veterinary Medicine, İstanbul University-Cerahpaşa, İstanbul, Turkey.

Article Synopsis
  • The study aimed to evaluate the impact of hydrophilic statins (pravastatin and rosuvastatin) on adipokine levels and glucose metabolism in diabetic rats.
  • Diabetic rats treated with pravastatin showed improvements in body weight and fasting blood glucose levels, along with increased adiponectin and vaspin, while rosuvastatin did not significantly impact these factors.
  • Overall, pravastatin was found to be more effective than rosuvastatin in improving metabolic parameters in diabetic rats, suggesting its beneficial role in glucose regulation.
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Cancer is a type of non-communicable disease that is responsible for numerous deaths worldwide. Cancer incidence and mortality rates are on the rise due to a combination of factors, such as a growing population, aging, and poor dietary habits. The Özhatay & Cowley plant is an endemic plant in the area where it grows and is consumed by the public due to its various benefits.

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Background: We conducted a systematic review and meta-analysis to evaluate the safety and effectiveness of laparoscopic surgery (LS) compared to open surgery (OS) for congenital duodenal obstruction (CDO).

Methods: We conducted a literature review to find studies comparing LS and OS in neonates with CDO. A meta-analysis was conducted to systematically compile and compare factors, including surgical duration, time of feeding initiation, hospital length of stay (LOS), and postoperative complications.

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Purpose: Napabucasin (NP) is a natural compound that can suppress cancer cell proliferation and cell cycle by inhibition of the signal transducer and activator of transcription 3 (STAT3) gene. We examined the effects of NP on the proliferation and invasion of neuroblastoma cells (SH-SY5Y).

Methods: Human neuroblastoma SH-SY5Y cell line was used in this study.

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Our primary aim with this study was to build a patient-level classifier for stroke territory in DWI using AI to facilitate fast triage of stroke to a dedicated stroke center. A retrospective collection of DWI images of 271 and 122 consecutive acute ischemic stroke patients from two centers was carried out. Pretrained MobileNetV2 and EfficientNetB0 architectures were used to classify territorial subtypes as middle cerebral artery, posterior circulation, or watershed infarcts along with normal slices.

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This study investigates the relationship between ADHD symptom severity, metacognition, problematic social media use, and cyberbullying/cybervictimization in treatment-naïve adolescents. Understanding these relationships is vital for enhancing ADHD intervention strategies. Using a cross-sectional design, 97 adolescents meeting DSM-5 criteria for ADHD without any comorbidity and 97 healthy controls were assessed.

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Neuroprotective Effects of Bexarotene and Icariin in a Diabetic Rat Model.

Cureus

August 2024

Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Selcuk University, Konya, TUR.

Objective Type 2 diabetes mellitus (T2DM), a chronic metabolic disorder affecting over 400 million people globally, is increasingly recognized for its detrimental impact on the central nervous system. T2DM is linked to neurodegenerative diseases like Alzheimer's and vascular dementia. This study investigates the neuroprotective effects of bexarotene and icariin in a T2DM rat model, focusing on brain-derived neurotrophic factor (BDNF), glial fibrillary acidic protein (GFAP), and neurofilament-light chain (NfL) levels.

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