1,266 results match your criteria: "DiSSPA-Università degli Studi di Bari Aldo Moro[Affiliation]"
Front Artif Intell
December 2024
Laboratorio di Biostatistica e Bioinformatica, Fisica Sanitaria, I.R.C.C.S. Istituto Tumori "Giovanni Paolo II", Bari, Italy.
Objectives: Endometrial carcinosarcoma is a rare, aggressive high-grade endometrial cancer, accounting for about 5% of all uterine cancers and 15% of deaths from uterine cancers. The treatment can be complex, and the prognosis is poor. Its increasing incidence underscores the urgent requirement for personalized approaches in managing such challenging diseases.
View Article and Find Full Text PDFSci Total Environ
December 2024
Department of Biology, University of Naples Federico II, Via Vicinale Cupa Cintia 26, 80126 Naples, Italy. Electronic address:
Rare earth elements (REEs) encompass 15 lanthanides and play a crucial role in modern technology. Despite their essential uses, REEs are emerging environmental contaminants due to their growing presence in industrial, agricultural, and medical applications. For the first time, the species sensitivity distribution (SSD) approach was applied to REEs considering 58 papers including toxicity about Ce, Dy, Er, Gd, La, Lu, Nd, Pr, Sm, and Y.
View Article and Find Full Text PDFFront Oral Health
December 2024
Department of Innovative Technologies in Medicine & Dentistry, University of Chieti-Pescara, Chieti, Italy.
Aim: The intricate structure of the tooth root canals has a role in the colonization and biofilm formation in hidden areas that are hardly reached by standard endodontic treatments. This review aims at summarizing data from and studies for a better understanding of the application of cold atmospheric plasma (CAP) for the disinfection of dental root canals.
Methods: PubMed, Scopus, and Web of Science databases were screened.
Int J Dent
December 2024
Interdisciplinary Department of Medicine, Università degli Studi di Bari Aldo Moro, Bari 70124, Italy.
Bone regeneration plays a pivotal role in modern oral surgery, particularly in facilitating successful implant-prosthetic rehabilitation. This systematic review explores the regenerative potential of growth factors, such as platelet-rich fibrin (PRF) and concentrated growth factors (CGFs), when combined with various types of scaffolds in bone augmentation procedures, including guided bone regeneration, split crest, sinus lift (SL), and alveolar ridge preservation. A comprehensive search strategy yielded 18 relevant studies, which were analyzed for bone formation and stabilization outcomes.
View Article and Find Full Text PDFMol Cytogenet
December 2024
Dipartimento di Bioscienze, Biotecnologie e Ambiente, Università degli Studi di Bari "Aldo Moro", Bari, Italy.
Ring chromosome 18 (r(18)) is a rare chromosomal abnormality characterized by the circular rearrangement of chromosome 18, which presents significant challenges in genotype-phenotype correlations due to variability in deletions across the 18p and 18q arms. We report the case of a pediatric patient with a de novo ring chromosome 18, diagnosed by karyotype analysis and confirmed by high-resolution SNP arrays. The patient exhibited pathogenic copy number variants (CNVs) in the 18p11.
View Article and Find Full Text PDFDeveloping sigma-1 receptor (S1R) modulators is considered a valuable therapeutic strategy to counteract neurodegeneration, cancer progression, and viral infections, including COVID-19. In this context, tools capable of accurately predicting S1R affinity are highly desirable. Herein, we present a panel of 25 classifiers trained on a curated dataset of high-quality bioactivity data of small molecules, experimentally tested as potential S1R modulators.
View Article and Find Full Text PDFPolymers (Basel)
November 2024
Chemistry Department, University of Bari Aldo Moro, Via E. Orabona 4, 70126 Bari, Italy.
Polycarbonate (PC) is a highly versatile plastic material that is extensively utilized across various industries due to its superior properties, including high impact strength and heat resistance. However, its durability presents significant challenges for recycling and waste management. Polycarbonate is a thermoplastic polymer representative of the class of condensation reaction polymers obtained from the reaction of bisphenol A (BPA) and a carbonyl source, such as phosgene or alkyl and aryl carbonate.
View Article and Find Full Text PDFG Ital Cardiol (Rome)
December 2024
Cardiologia 1-Emodinamica, Dipartimento Cardiotoracovascolare "A. De Gasperis", ASST Grande Ospedale Metropolitano Niguarda, Milano.
Sci Rep
November 2024
School of Earth System Science, Tianjin University, 92 Weijin Road, Tianjin, 300072, China.
Soil biogenic components are subject to continuous sequestration, and export from soils into the surrounding air and water environments. However, the processes involving the stability or lability of their mineral states remain still unclear. To assess these issues, we have measured various biogenic components in a number of agricultural, forest, grassland, and deep soils, as well as desert sands from Inner Mongolia, both in the solid state and liquid extracts.
View Article and Find Full Text PDFAnn Jt
October 2024
1Orthopaedic and Trauma Clinic, Department of Surgical Sciences, University of Cagliari, Policlinico Universitario Duilio Casula, AOU Cagliari, Monserrato, Cagliari, Italy; 2Department of Translational Biomedicine and Neuroscience, Università degli Studi di Bari Aldo Moro, Bari, Italy.
Adv Sci (Weinh)
November 2024
Dipartimento di Chimica and Centre for Colloid and Surface Science, Università degli Studi di Bari Aldo Moro, Bari, 20125, Italy.
The electric dipoles of proteins in a biolayer determine their dielectric properties through the polarization density P. Hence, its reproducibility is crucial for applications, particularly in bioelectronics. Biolayers encompassing capturing antibodies covalently bound at a biosensing interface are generally preferred for their assumed higher stability.
View Article and Find Full Text PDFG Ital Nefrol
October 2024
U.O.C. di Nefrologia e Dialisi, Ospedale Generale Regionale "F. Miulli", Acquaviva delle Fonti (BA).
Central venous catheter-related thrombosis is a frequent non-infectious complication, typically associated with catheter dysfunction and hemodialysis inadequacy. Central venous catheters (CVCs) are categorized into non-tunnelled and tunnelled types, wherein the choice depends on patient's clinical conditions and the diagnostic and therapeutic workup. Tunnelled CVCs (tCVCs) are sought whenever an arteriovenous fistula is unfeasible or as primary access in patients with poor prognosis.
View Article and Find Full Text PDFMolecules
October 2024
Dipartimento di Chimica, Università degli Studi di Bari "Aldo Moro", Via Orabona 4, 70126 Bari, Italy.
The chemical characterization of natural products is often a complex task that demands powerful analytical techniques. Liquid chromatography with high-resolution tandem mass spectrometry (HRMS/MS) is often employed, yet it can face hard challenges when isomeric species are present, and reference standards are lacking. In such cases, the confidence level in compound identification can be significantly improved by the collection of orthogonal information on target analytes.
View Article and Find Full Text PDFEntropy (Basel)
October 2024
Complex Systems Lab, Department of Physics, Indian Institute of Technology Indore, Khandwa Road, Indore 453552, India.
In stock markets, nonlinear interdependencies between various companies result in nontrivial time-varying patterns in stock prices. A network representation of these interdependencies has been successful in identifying and understanding hidden signals before major events like stock market crashes. However, these studies have revolved around the assumption that correlations are mediated in a pairwise manner, whereas, in a system as intricate as this, the interactions need not be limited to pairwise only.
View Article and Find Full Text PDFPhys Med
November 2024
Medical Physics Department, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Via F. Gallini 2, 33081 Aviano, Italy.
Purpose: A novel and unconventional approach to a machine learning challenge was designed to spread knowledge, identify robust methods and highlight potential pitfalls about machine learning within the Medical Physics community.
Methods: A public dataset comprising 41 radiomic features and 535 patients was employed to assess the potential of radiomics in distinguishing between primary lung tumors and metastases. Each participant developed two classification models using: (i) all features (base model); (ii) only robust features (robust model).
Heart Rhythm
October 2024
Cardiology and Arrhythmology Clinic, University Hospital "Azienda Ospedaliero-Universitaria delle Marche," Ancona, Italy; Department of Biomedical Sciences and Public Health, Marche Polytechnic University, Ancona, Italy.
Background: The HeartLogic algorithm (Boston Scientific, St Paul, MN) integrates data from implantable cardioverter-defibrillator (ICD) sensors to predict heart failure (HF) decompensation: first (S1) and third (S3) heart sounds, intrathoracic impedance, respiration rate, ratio of respiration rate to tidal volume (RSBI), and night heart rate.
Objective: This study assessed the relative changes in ICD sensors at the onset of HeartLogic alerts, their association with patient characteristics, and outcomes.
Methods: The study included 568 patients with HF carrying ICDs (CRT-D, n = 410) across 26 centers, with a median follow-up of 26 months.
Chempluschem
December 2024
Dipartimento di Chimica, Università Degli Studi di Bari "Aldo Moro", Via Orabona 4, 70125, Bari, Italy.
Diatoms are photosynthetic microalgae widely diffused around the globe and well adapted to thrive in diverse environments. Their success is closely related to the nanostructured biosilica shell (frustule) that serves as exoskeleton. Said structures have attracted great attention, thanks to their hierarchically ordered network of micro- and nanopores.
View Article and Find Full Text PDFInorg Chem
October 2024
Department of Earth Sciences, Sapienza University of Rome, Piazzale Aldo Moro 5, I-00185 Rome, Italy.
Olivines are naturally occurring silicates consisting of isolated (SiO) tetrahedra linked through 1O and 2O octahedra. In this study, we report the structural and crystal-chemical characterization of synthetic olivine crystals containing up to 25% Li-Fe synthesized using the flux growth technique. Based on site scattering, <1-O> and <2-O> mean bond lengths, and charge neutrality of the chemical formula, we found a perfect ordering of Li and Fe at the two distinct 1 and 2 sites.
View Article and Find Full Text PDFSci Rep
October 2024
Dipartimento Di Chimica, Università Degli Studi Di Bari "Aldo Moro", Via E. Orabona 4, 70126, Bari, Italy.
Environ Res
December 2024
School of Earth System Science, Tianjin University, 92 Weijin Road, Tianjin, 300072, China; Tianjin Key Laboratory of Earth Critical Zone Science and Sustainable Development in Bohai Rim, Tianjin University, 92 Weijin Road, Tianjin, 300072, China. Electronic address:
Glaciers play key roles in capturing, storing, and transforming global carbon and nitrogen, thereby contributing markedly to their cycles. However, an integrated mechanistic approach is still lacking regarding glacier's primary producers (PP), in terms of stable dissolved inorganic carbon isotope (δC-DIC) and its relationship with dissolved carbon and nitrogen transformation d ynamic changes/cycling. Here, we sampled waters from glaciers, streams, tributaries, and the Indus River (IR) mainstream in the Upper IR Basin, Western Himalaya.
View Article and Find Full Text PDFRheumatology (Oxford)
September 2024
Unit of Rheumatology, Catholic University of the Sacred Heart, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Background: Mycophenolate mofetil (MMF) is a mainstay for the treatment of systemic sclerosis (SSc). The occurrence and implications of MMF-related adverse events on drug retention rates in real life remain poorly defined. We aimed to determine the MMF retention rate and to investigate the causes and patterns of discontinuation, adverse events (AEs) and treatment options used after discontinuation.
View Article and Find Full Text PDFJ Endocrinol Invest
September 2024
Centro per le Malattie Endocrine e Metaboliche, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Italy.
Purpose: Physical exercise is a key component in the treatment of type 2 diabetes and plays an important role in maintaining a healthy glucose metabolism even in healthy subjects. To date, no studies have investigated the effect of a single bout of aerobic physical exercise on glucose metabolism in young, moderately active, healthy adults.
Methods: We performed an OGTT 7 days before and 24 h after a single bout of physical exercise, to evaluate 1-hour post-load plasma glucose and surrogate indexes of insulin sensitivity and insulin secretion.
Front Plant Sci
September 2024
Dipartimento di Scienze del Suolo, della Pianta e degli Alimenti, Università degli Studi di Bari Aldo Moro, Bari, Italy.
Data Brief
December 2024
Università degli Studi di Bari Aldo Moro, Largo Abbazia Santa Scolastica, 70124 Bari, Italy.
The dataset collects and harmonizes financial data about public works in Italy, focusing on soil defence investments. The data are sourced from three distinct platforms: the Italian Ministry of Economics and Finance's open data platform OpenBDAP, the OpenCoesione website, concerned with interventions framed in cohesion policies financed by additional resources from the European and national budgets, and the ReNDiS database, provided by the Italian Institute for Environmental Protection and Research (ISPRA), that exclusively gathers information about public works in soil defence. The data records belonging to these three sources are linked by a unique project code (CUP), ensuring that there is no duplication of data.
View Article and Find Full Text PDFMethods Mol Biol
September 2024
Dipartimento di Chimica, Università degli studi di Bari Aldo Moro, Bari, Italy.
Developmental toxicity is key human health endpoint, especially relevant for safeguarding maternal and child well-being. It is an object of increasing attention from international regulatory bodies such as the US EPA (US Environmental Protection Agency) and ECHA (European CHemicals Agency). In this challenging scenario, non-test methods employing explainable artificial intelligence based techniques can provide a significant help to derive transparent predictive models whose results can be easily interpreted to assess the developmental toxicity of new chemicals at very early stages.
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