Insomnia and Associated Social Factors among Medical Support Staff during the Covid-19 Pandemic.

The pandemic Covid-19 not only caused great public health problems but also caused enormous distress, especially for medical staff. The cross-sectional study aimed to investigate the prevalence rate of insomnia and to confirm the social factors among medical support staff in hospitals during the Covid-19 pandemic from 1st July 2020 to December 31st 2020. This study was conducted at Dhaka Medical College and Hospital (DMCH), Kurmitola General Hospital (KGH), Kuwait Bangladesh Friendship Government Hospital and Mugda Medical College and Hospital located at Dhaka and Tungipara UHC from Tungipara, Gopalganj, Bangladesh.

Study on Drug Use Pattern in Dermatology Out-Patient Department: A Cross-Sectional Study in a Tertiary Care Teaching Hospital, Dhaka, Bangladesh.

Now-a-days, all over the world, skin disease are the fourth most common cause of disability. A significant amount of patient attending the dermatology outdoor of any major hospital in a daily basis. Irrational drug prescribing is a common contemplation in clinical practice.

Variation of Neck Length on Anterior and Posterior Aspect of Femur in Bangladeshi People.

The regional variation of the femur bone is influenced by sex, stature geographical area and heredity, as the environment plays an important role in the developmental process. This cross-sectional descriptive purposive study was done on 150 (64 right and 86 left) fully ossified dry human femur of Bangladeshi people to find out the variation of neck length on anterior and posterior aspect. Sample was collected in the Department of Anatomy, Mymensingh Medical College, Bangladesh from January 2019 to December 2019.

International Staging System Status and Trend of Relapse in Multiple Myeloma Cases in a Tertiary Level Health Care.

Multiple myeloma (MM) is a haematological neoplasm of mature B-cell lineage origin. It is characterized by abnormal clonal proliferation of plasma cells and presence of monoclonal protein in serum and / or urine. This study was conducted to observe the International Staging System (ISS) status and trends of relapse.

Analysis of Liver Function Tests in Dengue Infected Patients.

Dengue is a mosquito-borne infection that in recent years has become a vital disease of international public health concern. Dengue virus infections and illness when symptomatic, that patients tend to present with a significantly wide variety manifestation. The aim of the study was to gauge liver dysfunction in patients with dengue infections.

Determination of High-Sensitivity C-reactive protein in Patient with Early Parkinson's disease.

Parkinson's disease (PD) is a common neurodegenerative disorder. The pathogenesis of PD is unknown till now. The high-sensitivity C-reactive protein (CRP) is a non-specific biochemical marker of inflammation.

Urinary Tract Infection in Systemic Lupus Erythematosus: Report from A Developing Country.

Urinary tract infection (UTI) is one of the important causes of morbidity and mortality in Systemic lupus erythematosus (SLE). To calculate the frequency, organism and risk factors for UTI in SLE. This observational study was conducted in the lupus clinic in the department of Rheumatology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh from September 2012 to January 2014.

Serum Calcium Level in Patients with Essential Hypertension.

Hypertension is the leading risk factor for death and disability globally, particularly in Bangladesh. Serum calcium is supposed to be linked with the pathophysiology of hypertension, though various studies have shown contradictory results. Hence, this study was conducted to evaluate the role of serum calcium level in essential hypertensive patients.

Reference interval of Hemoglobin: Findings from a Cross Sectional Study in Adult Population of Dhaka, Bangladesh.

Hemoglobin is a common hematological parameter assessed in laboratory and also an important tool for clinical management of patients. Reference values being used in most laboratories in our country, have been provided from the established reference values of developed countries. Hemoglobin concentration varies usually due to age, sex, attitude, ethnic origin, dietary habits, socioeconomic status and environmental factor.

Causes and Consequences of Delayed Presentation of Muscle Invasive Urinary Bladder Carcinoma.

Lag times for the diagnosis and treatment of urinary bladder cancer are generally longer which reduces the chances of achieving cures. This study was carried out at the Urology Department of Bangabandhu Sheikh Mujib Medical University, Dhaka and a Urology Center in a private hospital in Dhaka, Bangladesh from July 2007 to June 2008 on patients of newly diagnosed muscle invasive bladder carcinoma. This study was intended to assess the delay encountered by the patients and its consequences in the process of diagnosis and treatment of bladder cancer.

Outcome of Percutaneous Nephrolithotomy by Using Pneumatic Lithotripsy Alone and In Combination with Ultrasonic Lithotripsy.

Percutaneous nephrolithotomy (PCNL) is the gold standard treatment for large kidney stones. Recent advancements in endoscopic technology and operative techniques have significantly increased the success rate of PCNL while reducing associated complications and morbidity. A key development contributing to this progress is the introduction of various new lithotripter techniques, which facilitate rapid stone fragmentation and clearance.

Evaluation of Pelvic Pathology of Subfertile Women by Transvaginal Sonography and Correlation with Laparoscopic Findings.

Damage of fallopian tube, endometriosis, fibroid uterus, adenomysis and polycystic ovary syndrome are the major pelvic pathology that causes subfertility. Although there are many diagnostic tests available, the clinical presentation of each patient can usually be linked to specific and efficient testing strategies. Transvaginal sonographic (TVS) imaging is an effective, easy to use, safe and readily available noninvasive means to evaluate fertility potential.

Modification of cotton gauze using Cynodon dactylon (Bermuda grass) and assessment of the chemical and antimicrobial properties.

Bermuda grass (Cynodon dactylon) is a tropical grass found in all tropical and subtropical areas. It is widely found in Bangladesh and well known for its antimicrobial properties. Cotton gauze is a woven cloth which is used for wound dressing and wound cushioning.

Therapeutic potential inhibitor for dipeptidyl peptidase IV in diabetic type 2: in silico approaches.

Diabetes mellitus (DM) is a metabolic disease marked by an excessive rise in blood sugar (glucose) levels caused by a partial or total absence of insulin production, combined with alterations in the metabolism of proteins, lipids, and carbohydrates. The International Diabetes Federation estimates that 425 million individuals globally had diabetes in 2017 which will be 629 million by 2045. Several medications are used to treat DM, but they have limitations and side effects including weight gain, nausea, vomiting, and damage to blood vessels and kidneys.

Retraction notice to "Multifaceted role of polyphenols in the treatment and management of neurodegenerative diseases"[Chemosphere 307 (2022) 136020].

This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/policies/article-withdrawal).

Estimating the cost-effectiveness of maternal respiratory syncytial virus (RSV) vaccination in Australia: A dynamic and economic modelling analysis.

Background: Respiratory syncytial virus (RSV) is a major cause of respiratory illness, with younger infants at greatest risk of hospitalisation. With the recent approval of a maternal RSV vaccine in Australia, it is timely to evaluate its potential costs and health benefits in Australia.

Methods: We applied an integrated dynamic and economic evaluation model to estimate specific outcomes of RSV disease and the cost-effectiveness of a year-round maternal RSV vaccination program in Australia.

Proteomic Analysis of Anticancer Effect of Myo-inositol in Human Prostate Cancer (DU-145) Cell Line.

Objective: This study investigated the potential anticancer properties of Myo-inositol on the DU-145 prostate cancer cell line.

Methods: The DU-145 cells have been treated to different doses of Myo-inositol in order to ascertain the half-maximal inhibitory concentration (IC50) using the trypan blue exclusion assay. The impact of Myo-inositol on proteomic profiles was evaluated using 2D gel electrophoresis and liquid chromatography-mass spectrometry (LC-MS).

The interplay of factors in metabolic syndrome: understanding its roots and complexity.

Metabolic syndrome (MetS) is an indicator and diverse endocrine syndrome that combines different metabolic defects with clinical, physiological, biochemical, and metabolic factors. Obesity, visceral adiposity and abdominal obesity, dyslipidemia, insulin resistance (IR), elevated blood pressure, endothelial dysfunction, and acute or chronic inflammation are the risk factors associated with MetS. Abdominal obesity, a hallmark of MetS, highlights dysfunctional fat tissue and increased risk for cardiovascular disease and diabetes.

Enhancement of Chondrogenic Differentiation in Bone Marrow-Derived Stem Cell Spheroids by Methanolic Extract: Insights into Concentration-Dependent mRNA Expression and Gene Clustering Analysis.

: L. has been utilized as a medicinal plant for centuries. This research sought to examine the effects of cumin methanolic extract (CMT) on the chondrogenic differentiation of human bone marrow-derived mesenchymal stem cells.

Metabolite Biomarkers for Early Detection of Pancreatic Ductal Adenocarcinoma: A Systematic Review.

Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies, with a poor prognosis. This poor prognosis is largely attributed to a late-stage diagnosis. Recent advancements in metabolomics have emerged as a promising avenue for biomarker discovery in PDAC.

Clinical and genomic characterization of Klebsiella pneumoniae infections in Dhaka, Bangladesh.

Background: Klebsiella pneumoniae (Kpn), a WHO priority pathogen with high rates of antimicrobial resistance (AMR), has emerged as a leading cause of hospital acquired pneumonia and neonatal sepsis.

Objective: We aimed to define the clinical characteristics of a cohort of patients with Kpn infection in Dhaka, Bangladesh and to perform phenotypic and genetic characterization of the associated isolates.

Methods: We retrospectively extracted clinical data about patients at Dhaka Medical College Hospital from whom Klebsiella spp was isolated from a clinical specimen collected between February and September 2022.

Relationship between functional independence and community integration of people with spinal cord injury in Bangladesh.

Design: Prospective, cross-sectional study.

Objectives: To determine the functional outcome and home and social integration of people who had spinal cord injury and completed their inpatient rehabilitation.

Setting: Centre for the Rehabilitation of the Paralysed (CRP), Bangladesh.

An umbrella review of meta-analysis to understand the effect of coffee consumption and the relationship between stroke, cardiovascular heart disease, and dementia among its global users.

Coffee has long been popular worldwide. The rise in lifestyle-related diseases such as cardiovascular disease, diabetes, stroke, dementia, and others has motivated coffee usage and illness prevalence studies. Some studies show coffee consumers are at risk for such diseases, whereas others show its active components protect them.

Disparities in telehealth utilization between US rural and urban areas during the COVID-19 pandemic.

Purpose: During the COVID-19 pandemic, telehealth services were expanded across the United States to meet the increased demand and safety requirements of care. This observational study aims to understand rural-urban differences in telehealth utilization during the early part of the COVID-19 pandemic.

Methods: Individual-level data from the National Health Interview Survey 2020-2021 (age ≥18) were analyzed for this study.