Assessment of Effect of Periodontal and Prosthodontic Therapy on Glycemic Control in Patients with Diabetes.

Background: Periodontitis is a chronic inflammatory disease of multifactorial etiology. The present study was conducted to assess the effect of periodontal and prosthodontic therapy on glycemic control in patients with diabetes.

Materials And Methods: 80 type II diabetics patients of both genders were divided into Group I (periodontal and prosthodontic therapy) and Group II (Healthy).

Assessment of Cases of Complete Denture Fracture.

Background: There are many causes and reasons associated with fractures of complete dentures. The present study assessed case of complete denture fracture.

Materials And Methods: One hundred and fifty complete denture wearers reported to the department of prosthodontics for correction of complete denture fracture were examined carefully.

Assessment of Effect of Menopause on Saliva and Oral Health Status.

Background: Women at menopausal period may frequently develop several oral mucosal disorders. Xerostomia is also a common finding among postmenopausal women. The present study was conducted to assess effect of menopause on saliva and dental health.

Determination of Role of Type 16 Human Papillomavirus and Risk Factors in Assessing Oropharyngeal Cancer Survival.

Background: It is ascertained that the survival rate of patients infected with type 16 human papillomavirus (HPV16) positive is better as compared to those infected with HPV16 negative. The present study was conducted to determine rgw role of HPV16 and risk factors in assessing oropharyngeal cancer (OPC) death.

Methodology: A total of 102 clinically and histologically proven cases of oral pharyngeal cancer were included.

Efficacy of Routinely used Analgesics in Management of Pulpal Pain Postoperatively a Clinical Study.

Aim: The aim of this study was to evaluate the efficacy of various routinely used analgesics in the management of pulpal pain preoperatively.

Materials And Methods: A total of 150 patients were randomly selected and divided into five groups each. At initial visit, a self-administered questionnaire was given, and patients were asked to mark on the Visual Analog Scale (VAS) indicating severity of pain at that moment which is taken as a pretreatment VAS score.

Analysis of Age and Gender-Related Changes in Gingival Width in Patients of Known Population: A Cross-sectional Study.

Aims: The present study was conducted for analyzing age and gender-related alterations in gingival width (GW) in patients of known population.

Materials And Methods: Two hundred and ten healthy participants were enrolled in the present research. All the participants were divided into the following study groups with seventy participants in each group based on their age: adolescents, young adults, and older adults.

Evaluation of effect of gestational diabetes mellitus on composition of the initial oral microbiota of neonates.

Background: Gestational diabetes mellitus (GDM) is one of the commonly occurring high-risk obstetric complications that accounts for 4%-9% of total pregnancies. The present study was an attempt to assess the effect of GDM on composition of the neonatal oral microbiota.

Materials And Methods: In this study, oral samples from 155 full-term vaginally delivered newborns were collected with sterile swabs.

Anticancer potential of some imidazole and fused imidazole derivatives: exploring the mechanism epidermal growth factor receptor (EGFR) inhibition.

Imidazole-based epidermal growth factor receptor (EGFR) inhibitors were computationally designed and synthesized. All the compounds were assessed for their anti-proliferative activity against five cancer cell lines, , MDA-MB-231 (breast), T47D (breast) and MCF-7 (breast), A549 (lung) and HT-29 (colorectal). Compounds and emerged as better anticancer molecules with no toxicity towards normal cells.

A comparative evaluation of smear layer removal by using ethylenediamine tetraacetic acid, citric acid, and maleic acid as root canal irrigants: An scanning electron microscopic study.

Introduction: Irrigants remove or dissolve smear layer formed during instrumentation. Thus it is important to study the effect of different irrigant solutions on smear layer removal.

Objectives: The aim of this study is to determine which irrigant effectively removes the smear layer from the coronal, middle, and apical third of the root canal.

An insight into patient's perceptions regarding root canal treatment: A questionnaire-based survey.

Background: A key setback of root canal treatment (RCT) is that most patients lack adequate knowledge about it. Understanding and identifying the factors that hinder or discourage patients from undergoing RCT is necessary to adequately address the issue. The review of literature shows that there is a paucity of data about the awareness and acceptance of RCT among patients in Indian population.

Evaluation of Surface Roughness and Hardness of Newer Nanoposterior Composite Resins after Immersion in Food-Simulating Liquids.

Introduction: Restorative resins during their prolonged use are exposed to variety foods and beverages are subjected to wear, degradation, and staining resulting in failure of restoration and require replacement. This study is aimed to evaluate surface roughness and hardness of five commercially available posterior resin composites following exposure to various food-simulating liquids (FSLs).

Materials And Methods: Specimens were immersed in distilled water, ethanol, citric acid, and air and later examined using a profilometer, scanning electron microscope for the surface profiles.

Antibiotic abuse during endodontic treatment: A contributing factor to antibiotic resistance.

Antibiotic resistance is one of our most serious global health threats. The adverse effects of overusing and misusing antibiotics are highly publicized in the health professional literature. Antibiotic abuse occurs during routine endodontic treatment and there are deficiencies in knowledge regarding prescribing antibiotic and appropriate prophylactic antibiotic use.

Evaluation of Effect of Bisphosphonates on Dental Implant Therapy in Postmenopausal Women Using Cone Beam Computed Tomography.

Aim: Osteoporosis is one of the diseases which show significant bone mass reduction especially in post menopausal women. The present study was conducted to determine the effect of Bisphosphonates (BP) on alveolar bone and dental implant therapy in women after menopause.

Materials And Methods: The present study was conducted on 30 postmenopausal women who received at least one dental implant in the last 5 years.

3P's in Retreatment Endodontics-An Often Forgotten Virtue.

Separation of instrument in the root canal is a common mishap that occurs during the cleaning and shaping procedure. So many different methods have been developed to retrieve fractured instruments from root canal. Separated instrument leads to incomplete cleaning of root canal and eventually causes posttreatment disease.

Detection of human papilloma virus-E6/E7 proteins of high-risk human papilloma virus in saliva and lesional tissue of oral squamous cell carcinoma patients using nested multiplex polymerase chain reaction: A comparative study.

Introduction: Human papilloma virus (HPV)-associated oral squamous cell carcinoma (OSCC) shows different biological behavior as compared to tobacco-induced OSCC. Mere presence of HPV in OSCC is of no clinical significance; however, the integration of HPV-DNA through E6/E7 gene into the host genome is important as it affects the development and progression of OSCC.

Aim: The aim of this study was to determine the presence of E6/E7 proteins of high-risk (HR) HPV (HPV16 and HPV18) in saliva as well as lesional tissue of OSCC patients and to determine the use of saliva as an alternative to tissue for E6 and E7 proteins in OSCC.

Assessment of Lingual Concavities in Submandibular Fossa Region in Patients requiring Dental Implants-A Cone Beam Computed Tomography Study.

Aim: The present study was aimed at assessing the lingual concavities in the submandibular fossa region in patients requiring dental implants with the help of cone beam computed tomography (CBCT).

Materials And Methods: The present study included 140 patients who visited the department with the missing mandibular posterior teeth. CBCT images were obtained using planmeca machine.

Taurine: A potential mediator for periodontal therapy.

Taurine or 2-aminoethanesulfonic has many fundamental biological roles such as conjugation of bile acids, antioxidation, osmoregulation, membrane stabilization, and modulation of calcium signaling. It is essential for cardiovascular function and development and function of the skeletal muscle, the retina, and the central nervous system. Functions of taurine include osmoregulation; membrane stabilization; modulation of calcium levels; and antioxidation, antiapoptotic, anti-inflammatory, and antilipid activities.

A Randomized, Double-Blind, Placebo-Controlled Trial on Clinical Efficacy of Topical Agents in Reducing Pain and Frequency of Recurrent Aphthous Ulcers.

Introduction: Recurrent Aphthous Ulcers (RAU) is one of the most common oral ulcerative Disease of the oral mucosa with high recurrence rate. Standard topical treatment options provide symptomatic relief with few have been found to be effective in treating or relieving the symptoms.

Aim: The study aimed to evaluate the clinical efficacy of various topical agents in order to find the better treatment modality so as to decrease the number, size, exudate level and discomfort associated with pain with RAU.

Intraoral Sebaceous Carcinoma: Case Report of a Rare Tumor Emphasizing the Histopathological Differential Diagnosis.

Background: Sebaceous carcinoma (SC) is an uncommon cutaneous malignancy, usually occurring predominantly in the eyelids and only occasionally involving the oral cavity. Sebaceous carcinoma (SC) is a rare malignancy. Only 10 cases of sebaceous carcinoma of the oral cavity have been reported so far.

Evaluation of Mechanical Properties of Newer Nanoposterior Restorative Resin Composites: An Study.

Introduction: Tooth coloured restorative materials are subjected to various physical, mechanical conditions in oral conditions. Many newer composites with improved physical and mechanical properties are introduced for clinical use. There are not many clinical studies on recent composites.

Estimation of cortisol levels in patients with premalignant disorders and oral squamous cell carcinoma.

Introduction: Oral cancer has been a scourge on the human population that drastically affects the quality of life-causing chronic anxiety and depression leading to disturbance in hypothalamus pituitary axis reflected by cortisol hormone dysregulation. Stress hormones affect tumor progression at different levels such as initiation, tumor growth and metastasis. Cortisol dysregulation has been reported in other malignancies; however, a thorough review of English literature revealed only anecdotal studies investigating it in patients with oral squamous cell carcinoma (OSCC).

Assessment of Lipid Peroxidation Levels and Total Antioxidant Status in Chronic and Aggressive Periodontitis Patients: An in vivo Study.

Introduction: Periodontitis is a common problem affecting a significant population of the world. For the assessment of oxidative stress of an individual, total oxidation status (TOS) and total antioxidant capacity (TAOC) are the significant biomarkers. Hence, we planned the present study to assess malondialde-hyde (MDA), TOS, TAOC levels, and oxidative stress index (OSI) in generalized aggressive periodontitis (GP) and chronic periodontitis (CP) patients.