Roflumilast extenuates inflammation and oxidative stress in cadmium-induced hepatic and testicular injury in rats.

Roflumilast (ROF), a highly selective phosphodiesterase-4 inhibitor, has proven anti-inflammatory and immunomodulatory effects on the pulmonary system. However, the protective effects of ROF on cadmium (Cd)-induced hepatic and testicular injury has never been investigated. Adult male Sprague Dawley rats were acutely intoxicated with CdCl (3 mg/Kg, ip, qd, for 5 days).

Phytosynthesis of Silver Nanoparticle (AgNPs) Using Aqueous Leaf Extract of (Retz.) DC. and Their Multi-Potent Biological Activity: An Eco-Friendly Approach.

Green synthesis of silver nanoparticles (AgNPs) has gained greater interest among chemists and researchers in this current scenario. The present research investigates the larvicidal and anti-proliferation activity of AgNPs derived from aqueous leaf extract (-ALE) as a potential capping and reducing candidate. The synthesized AgNPs were characterized through-UV-spectra absorption peak at 425 nm.

Defense Responses and Metabolic Changes Involving Phenylpropanoid Pathway and PR Genes in Squash ( L.) following Infection.

The current study focuses on the effects of (CMV) infection on phytochemical changes and pathogenesis- and phenylpropanoid pathway-associated gene activities in squash ( L.) plants during a time course of 2 to 12 days post inoculation (dpi). The identity of the CMV isolate was confirmed by DAS-ELISA, TEM, and coat protein gene sequence.

RNA Interference Suppression of v-ATPase B and Juvenile Hormone Binding Protein Genes Through Topically Applied dsRNA on Tomato Leaves: Developing Biopesticides to Control the South American Pinworm, (Lepidoptera: Gelechiidae).

The South American pinworm (Meyrick) (Family: Gelechiidae) is one of the most devastating lepidopteran pests in the developing countries of South America, Africa, and Asia. This pest is classified as the most serious threat for tomato production worldwide. In the present study, we analyzed RNAi-mediated control through exogenously applied dsRNA delivery on tomato.

Efficacy of Precocene I from as an Effective Bioactive Molecules against the Fab. and Its Impact on Savigny.

The sustainability of agroecosystems are maintained with agro-chemicals. However, after more than 80 years of intensive use, many pests and pathogens have developed resistance to the currently used chemistries. Thus, we explored the isolation and bioactivity of a chemical compound, Precocene I, isolated from the perennial grass, (L.

Toxicity of Bioactive Molecule Andrographolide against Fab and Its Binding Potential with Detoxifying Enzyme Cytochrome P450.

Fab. is a polyphagous pest causing damage to many agriculture crops leading to yield loss. Recurrent usage of synthetic pesticides to control this pest has resulted in resistance development.